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PDB: 225 件

7JNA
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Cryo-EM structure of human proton-activated chloride channel PAC at pH 8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel
著者Lu, W, Ruan, R, Du, J.
登録日2020-08-04
公開日2020-11-11
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures and pH-sensing mechanism of the proton-activated chloride channel.
Nature, 588, 2020
7JNC
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cryo-EM structure of human proton-activated chloride channel PAC at pH 4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel
著者Lu, W, Ruan, R, Du, J.
登録日2020-08-04
公開日2020-11-11
最終更新日2020-12-23
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Structures and pH-sensing mechanism of the proton-activated chloride channel.
Nature, 588, 2020
6CUD
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Structure of the human TRPC3 in a lipid-occupied, closed state
分子名称: (2R)-3-hydroxypropane-1,2-diyl dihexanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Lu, W, Du, J, Fan, C, Choi, W.
登録日2018-03-25
公開日2018-05-16
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the human lipid-gated cation channel TRPC3.
Elife, 7, 2018
7MBS
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Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (open state)
分子名称: (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ruan, Z, Lu, W, Du, J, Haley, E.
登録日2021-04-01
公開日2021-07-07
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY
主引用文献Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
Nat.Struct.Mol.Biol., 28, 2021
7MBR
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BU of 7mbr by Molmil
Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (apo state)
分子名称: (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ruan, Z, Lu, W, Du, J, Haley, E.
登録日2021-04-01
公開日2021-07-07
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY
主引用文献Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
Nat.Struct.Mol.Biol., 28, 2021
7MBT
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Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (low calcium occupancy in the transmembrane domain)
分子名称: (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ruan, Z, Lu, W, Du, J, Haley, E.
登録日2021-04-01
公開日2021-07-07
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY
主引用文献Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
Nat.Struct.Mol.Biol., 28, 2021
7MBQ
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BU of 7mbq by Molmil
Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mM calcium
分子名称: (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ruan, Z, Lu, W, Du, J, Haley, E.
登録日2021-04-01
公開日2021-07-07
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
Nat.Struct.Mol.Biol., 28, 2021
7MBU
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BU of 7mbu by Molmil
Cryo-EM structure of zebrafish TRPM5 E337A mutant in the presence of 5 mM calcium (high calcium occupancy in the transmembrane domain)
分子名称: (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ruan, Z, Lu, W, Du, J, Haley, E.
登録日2021-04-01
公開日2021-07-07
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY
主引用文献Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
Nat.Struct.Mol.Biol., 28, 2021
7MBV
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BU of 7mbv by Molmil
Cryo-EM structure of zebrafish TRPM5 in the presence of 5 mM calcium and 0.5 mM NDNA
分子名称: (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ruan, Z, Lu, W, Du, J, Haley, E.
登録日2021-04-01
公開日2021-07-07
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
Nat.Struct.Mol.Biol., 28, 2021
7MBP
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BU of 7mbp by Molmil
Cryo-EM structure of zebrafish TRPM5 in the presence of 1 mM EDTA
分子名称: (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Ruan, Z, Lu, W, Du, J, Haley, E.
登録日2021-04-01
公開日2021-09-22
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
Nat.Struct.Mol.Biol., 28, 2021
6IP0
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BU of 6ip0 by Molmil
Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with AKG
分子名称: 2-OXOGLUTARIC ACID, NICKEL (II) ION, SULFATE ION, ...
著者Hu, H, Du, J.
登録日2018-11-01
公開日2019-04-10
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor.
Nat Commun, 10, 2019
6IP4
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BU of 6ip4 by Molmil
Crystal structure of Arabidopsis thaliana JMJ13 catalytic domain in complex with NOG and an H3K27me3 peptide
分子名称: Arabidopsis JMJ13, Histone H3.2, N-OXALYLGLYCINE, ...
著者Hu, H, Du, J.
登録日2018-11-02
公開日2019-04-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Arabidopsis H3K27me3 demethylase JUMONJI 13 is a temperature and photoperiod dependent flowering repressor.
Nat Commun, 10, 2019
6J9B
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BU of 6j9b by Molmil
Arabidopsis FUS3-DNA complex
分子名称: B3 domain-containing transcription factor FUS3, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3')
著者Hu, H, Du, J.
登録日2019-01-22
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
7XPJ
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BU of 7xpj by Molmil
crystal structure of rice ASI1 BAH domain
分子名称: BAH domain-containing protein
著者Yuan, J, Du, J.
登録日2022-05-04
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Molecular basis of locus-specific H3K9 methylation catalyzed by SUVH6 in plants.
Proc.Natl.Acad.Sci.USA, 120, 2023
7XPK
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BU of 7xpk by Molmil
crystal structure of rice ASI1 BAH domain in complex with a rice SUVH6 peptide
分子名称: Alpha-aminoacylpeptide hydrolase, BAH domain-containing protein
著者Yuan, J, Du, J.
登録日2022-05-04
公開日2023-01-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis of locus-specific H3K9 methylation catalyzed by SUVH6 in plants.
Proc.Natl.Acad.Sci.USA, 120, 2023
7ET4
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BU of 7et4 by Molmil
Crystal structure of Arabidopsis TEM1 AP2 domain
分子名称: AP2/ERF and B3 domain-containing transcription repressor TEM1, DNA (12-mer)
著者Hu, H, Du, J.
登録日2021-05-12
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis.
Proc.Natl.Acad.Sci.USA, 118, 2021
7VSQ
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BU of 7vsq by Molmil
Crystal strcuture of the tandem B-Box domains of CONSTANS
分子名称: ZINC ION, Zinc finger protein CONSTANS
著者Liu, R, Lv, X, Du, J.
登録日2021-10-27
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular basis of CONSTANS oligomerization in FLOWERING LOCUS T activation.
J Integr Plant Biol, 64, 2022
7VSP
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BU of 7vsp by Molmil
Crystal strcuture of the tandem B-Box domains of COL2
分子名称: ZINC ION, Zinc finger protein CONSTANS-LIKE 2
著者Lv, X, Liu, R, Du, J.
登録日2021-10-27
公開日2022-03-02
最終更新日2022-03-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular basis of CONSTANS oligomerization in FLOWERING LOCUS T activation.
J Integr Plant Biol, 64, 2022
6J9A
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BU of 6j9a by Molmil
Crystal structure of Arabidopsis thaliana VAL1 in complex with FLC DNA fragment
分子名称: B3 domain-containing transcription repressor VAL1, DNA (5'-D(*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*TP*C)-3'), DNA (5'-D(*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*TP*G)-3')
著者Hu, H, Du, J.
登録日2019-01-22
公開日2019-05-29
実験手法X-RAY DIFFRACTION (2.915 Å)
主引用文献Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
6J9C
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Crystal structure of Arabidopsis thaliana transcription factor LEC2-DNA complex
分子名称: B3 domain-containing transcription factor LEC2, DNA (5'-D(*CP*AP*AP*TP*CP*CP*AP*TP*GP*CP*AP*GP*AP*AP*T)-3'), DNA (5'-D(*GP*AP*TP*TP*CP*TP*GP*CP*AP*TP*GP*GP*AP*TP*T)-3')
著者Hu, H, Du, J.
登録日2019-01-22
公開日2019-05-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis.
Nat.Plants, 5, 2019
7DE9
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BU of 7de9 by Molmil
crystal structure of Arabidopsis RDM15 tudor domain in complex with an H3K4me1 peptide
分子名称: Histone H3.2, Transcriptional regulator
著者Song, Z, Du, J.
登録日2020-11-03
公開日2021-04-07
最終更新日2021-06-23
実験手法X-RAY DIFFRACTION (1.711 Å)
主引用文献A histone H3K4me1-specific binding protein is required for siRNA accumulation and DNA methylation at a subset of loci targeted by RNA-directed DNA methylation.
Nat Commun, 12, 2021
7VG2
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Cryo-EM structure of Arabidopsis DCL3 in complex with a 40-bp RNA
分子名称: CALCIUM ION, Dicer-like 3, TAS1a forward strand (5'-phosphorylation), ...
著者Wang, Q, Du, J.
登録日2021-09-14
公開日2021-10-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
7VG3
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Cryo-EM structure of Arabidopsis DCL3 in complex with a 30-bp RNA
分子名称: CALCIUM ION, Dicer-like 3, TAS1a RNA forward strand (5'-phosphorylated), ...
著者Wang, Q, Du, J.
登録日2021-09-14
公開日2021-10-27
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.73 Å)
主引用文献Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation.
Science, 374, 2021
7ET5
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BU of 7et5 by Molmil
Crystal structure of Arabidopsis TEM1 AP2 domain
分子名称: AP2/ERF and B3 domain-containing transcription repressor TEM1, SULFATE ION
著者Hu, H, Du, J.
登録日2021-05-12
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.052 Å)
主引用文献TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis.
Proc.Natl.Acad.Sci.USA, 118, 2021
7ET6
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Crystal structure of Arabidopsis TEM1 B3-DNA complex
分子名称: AP2/ERF and B3 domain-containing transcription repressor TEM1, FT-RY14-F, FT-RY14-R
著者Hu, H, Du, J.
登録日2021-05-12
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献TEM1 combinatorially binds to FLOWERING LOCUS T and recruits a Polycomb factor to repress the floral transition in Arabidopsis.
Proc.Natl.Acad.Sci.USA, 118, 2021

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