7MBS

Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (open state)

Summary for 7MBS

• Entry DOI: 10.2210/pdb7mbs/pdb
• EMDB information: 23740 23741 23742 23743 23744 23745 23746 23747 23748
• Descriptor: Transient receptor potential melastatin 5, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (6 entities in total)
• Functional Keywords: ion channel, trp channel, transport protein
• Biological source: Danio rerio (Zebrafish, Brachydanio rerio)
• Total number of polymer chains: 4
• Total formula weight: 537424.07

Authors

Ruan, Z.,Lu, W.,Du, J.,Haley, E. (deposition date: 2021-04-01, release date: 2021-07-07, Last modification date: 2021-07-28)

• Primary citation: Ruan, Z.,Haley, E.,Orozco, I.J.,Sabat, M.,Myers, R.,Roth, R.,Du, J.,Lu, W.; Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.; Nat.Struct.Mol.Biol., 28:604-613, 2021; PubMed: 34168372; DOI: 10.1038/s41594-021-00607-4

Experimental method

ELECTRON MICROSCOPY