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7MBS

Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (open state)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Transient receptor potential melastatin 5polymer1165132799.04UniProt (S5UH55)
Pfam (PF18139)
Pfam (PF00520)
Danio rerio (Zebrafish Brachydanio rerio)
2E, J, O, U
(A, B, C, D)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
3F, G, K, L, P...
(A, B, C, D)
CALCIUM IONnon-polymer40.18Chemie (CA)
4H, M, R, X
(A, B, C, D)
(25R)-14beta,17beta-spirost-5-en-3beta-olnon-polymer414.64Chemie (YUV)
5I, N, S, T
(A, B, C, D)
(2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranosidenon-polymer841.04Chemie (YUY)
6AA, BA, Y, Z
(C, D, A, B)
waterwater18.016Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight531196.0
Non-Polymers*Number of molecules20
Total formula weight6228.1
All*Total formula weight537424.1
*Water molecules are not included.

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PDB entries from 2025-08-27

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