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PDB: 225 件

3JAF
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Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine/ivermectin-bound state
分子名称: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1
著者Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E.
登録日2015-06-08
公開日2015-09-09
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.801 Å)
主引用文献Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
3JAE
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Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, glycine-bound state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1
著者Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E.
登録日2015-06-08
公開日2015-09-09
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
3JAD
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Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, strychnine-bound state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, STRYCHNINE
著者Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E.
登録日2015-06-08
公開日2015-09-09
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
6PXD
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BU of 6pxd by Molmil
CryoEM structure of zebra fish alpha-1 glycine receptor, Apo state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Glycine receptor subunit alphaZ1
著者Du, J, Lu, W, Gouaux, E.
登録日2019-07-25
公開日2021-02-10
最終更新日2022-08-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Mechanism of gating and partial agonist action in the glycine receptor.
Cell, 184, 2021
4IUP
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BU of 4iup by Molmil
crystal structure of Se-substituted arabidopsis thaliana SHH1 SAWADEE domain L200M/L218M mutant
分子名称: BETA-MERCAPTOETHANOL, CYMAL-4, SAWADEE HOMEODOMAIN HOMOLOG 1, ...
著者Du, J, Patel, D.J.
登録日2013-01-21
公開日2013-05-01
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IUT
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crystal structure of SHH1 SAWADEE domain in complex with H3K9me2 peptide
分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
著者Du, J, Patel, D.J.
登録日2013-01-21
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
3UIK
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crystal structure of human Survivin mutant K62Y/H80W in complex with H3(1-10) peptide
分子名称: Baculoviral IAP repeat-containing protein 5, ZINC ION, histone H3(1-10) peptide
著者Du, J, Patel, D.J.
登録日2011-11-04
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.701 Å)
主引用文献Structural Basis for Recognition of H3T3ph and Smac/DIABLO N-terminal Peptides by Human Survivin.
Structure, 20, 2012
4IUU
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Crystal structure of SHH1 SAWADEE domain in complex with H3K9me1 peptide
分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
著者Du, J, Patel, D.J.
登録日2013-01-21
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IUQ
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crystal structure of SHH1 SAWADEE domain
分子名称: CYMAL-4, SAWADEE HOMEODOMAIN HOMOLOG 1, ZINC ION
著者Du, J, Patel, D.J.
登録日2013-01-21
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.809 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
4IUV
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BU of 4iuv by Molmil
crystal structure of SHH1 SAWADEE domain in complex with H3K4me1K9me1 peptide
分子名称: CYMAL-4, Histone H3.2, H3(1-15)K9me3, ...
著者Du, J, Patel, D.J.
登録日2013-01-21
公開日2013-05-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.
Nature, 498, 2013
5GLE
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BU of 5gle by Molmil
The structure of Vibrio anguillarum775 AngB-ICL
分子名称: Ischorismate lyase
著者Du, J.S, Ma, Q.G.
登録日2016-07-10
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of Vibrio anguillarum775 AngB-ICL protein
To Be Published
6PUS
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BU of 6pus by Molmil
Human TRPM2 bound to ADPR and calcium
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 2
著者Du, J, Lu, W, Huang, Y.
登録日2019-07-18
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.
Elife, 8, 2019
6PUR
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BU of 6pur by Molmil
Human TRPM2 bound to ADPR
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Transient receptor potential cation channel subfamily M member 2
著者Du, J, Lu, W, Huang, Y.
登録日2019-07-18
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.
Elife, 8, 2019
6PUU
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BU of 6puu by Molmil
Human TRPM2 bound to 8-Br-cADPR and calcium
分子名称: (2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8 ,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate 8,10-dioxide, CALCIUM ION, Transient receptor potential cation channel subfamily M member 2
著者Du, J, Lu, W, Huang, Y.
登録日2019-07-18
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.
Elife, 8, 2019
5WXV
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BU of 5wxv by Molmil
The crystal structure of VabB-ICL domain from Vibrio anguillarum 775
分子名称: Isochorismate lyase
著者Du, J, Ma, Q.
登録日2017-01-09
公開日2018-01-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structures of isochorismatase domains from Vibrio anguillarum 775
To Be Published
3T2B
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BU of 3t2b by Molmil
Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, ligand free
分子名称: Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION
著者Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O.
登録日2011-07-22
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
3T2G
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BU of 3t2g by Molmil
Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, Y229F variant with DHAP
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION
著者Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O.
登録日2011-07-22
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
3T2D
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BU of 3t2d by Molmil
Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, FBP-bound form
分子名称: 1,6-di-O-phosphono-D-fructose, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION
著者Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O.
登録日2011-07-22
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
3T2C
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BU of 3t2c by Molmil
Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, DHAP-bound form
分子名称: 1,3-DIHYDROXYACETONEPHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION
著者Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O.
登録日2011-07-22
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
3T2F
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BU of 3t2f by Molmil
Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, soaked with EDTA and DHAP
分子名称: Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION
著者Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O.
登録日2011-07-22
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
6PUO
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Human TRPM2 in the apo state
分子名称: Transient receptor potential cation channel subfamily M member 2
著者Du, J, Lu, W, Huang, Y.
登録日2019-07-18
公開日2019-09-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel.
Elife, 8, 2019
3T2E
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BU of 3t2e by Molmil
Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, F6P-bound form
分子名称: FRUCTOSE -6-PHOSPHATE, Fructose-1,6-bisphosphate aldolase/phosphatase, MAGNESIUM ION
著者Du, J, Say, R, Lue, W, Fuchs, G, Einsle, O.
登録日2011-07-22
公開日2011-10-26
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase.
Nature, 478, 2011
7EPC
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BU of 7epc by Molmil
Cryo-EM structure of inactive mGlu7 homodimer
分子名称: Isoform 3 of Metabotropic glutamate receptor 7
著者Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q.
登録日2021-04-26
公開日2021-06-23
最終更新日2021-07-07
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021
7EPB
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BU of 7epb by Molmil
Cryo-EM structure of LY354740-bound mGlu2 homodimer
分子名称: (1S,2S,5R,6S)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylic acid, Anti-RON nanobody, Metabotropic glutamate receptor 2
著者Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q.
登録日2021-04-26
公開日2021-06-23
最終更新日2021-07-07
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021
7EPA
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BU of 7epa by Molmil
Cryo-EM structure of inactive mGlu2 homodimer
分子名称: Metabotropic glutamate receptor 2
著者Du, J, Wang, D, Fan, H, Tai, L, Lin, S, Han, S, Sun, F, Wu, B, Zhao, Q.
登録日2021-04-26
公開日2021-06-23
最終更新日2021-07-07
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structures of human mGlu2 and mGlu7 homo- and heterodimers.
Nature, 594, 2021

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