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PDB: 108 件

1KXK
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Crystal Structure of a RNA Molecule Containing Domain 5 and 6 of the Yeast ai5g Group II Self-splicing Intron
分子名称: MAGNESIUM ION, ai5g group II Self-splicing intron
著者Zhang, L, Doudna, J.A.
登録日2002-01-31
公開日2002-03-22
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into group II intron catalysis and branch-site selection.
Science, 295, 2002
1L8V
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Crystal Structure of a Mutant (C109G,G212C) P4-P6 Domain of the Group I Intron from Tetrahymena Thermophilia
分子名称: MAGNESIUM ION, P4-P6 RNA ribozyme domain
著者Battle, D.J, Doudna, J.A.
登録日2002-03-21
公開日2002-08-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Specificity of RNA-RNA Helix Recognition
Proc.Natl.Acad.Sci.USA, 99, 2002
2Y9H
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Structure A of CRISPR endoribonuclease Cse3 bound to 19 nt RNA
分子名称: 5'-R(*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP *GP*GP*DGP*AP*UP)-3', CSE3
著者Sashital, D.G, Jinek, M, Doudna, J.A.
登録日2011-02-14
公開日2011-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
Nat.Struct.Mol.Biol., 18, 2011
2Y8Y
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Structure B of CRISPR endoribonuclease Cse3 bound to 19 nt RNA
分子名称: 5'-R(*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP *GP*GP*DGP*AP*U)-3', CSE3
著者Sashital, D.G, Jinek, M, Doudna, J.A.
登録日2011-02-11
公開日2011-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
Nat.Struct.Mol.Biol., 18, 2011
2Y8W
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Structure of CRISPR endoribonuclease Cse3 bound to 20 nt RNA
分子名称: 5'-R(*UP*CP*CP*CP*CP*AP*CP*GP*CP*GP*UP*GP*UP*GP *GP*GP*DGP*AP*UP*G)-3', CSE3
著者Sashital, D.G, Jinek, M, Doudna, J.A.
登録日2011-02-11
公開日2011-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献An RNA-Induced Conformational Change Required for Crispr RNA Cleavage by the Endoribonuclease Cse3.
Nat.Struct.Mol.Biol., 18, 2011
2XLK
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Crystal structure of the Csy4-crRNA complex, orthorhombic form
分子名称: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A.
登録日2010-07-21
公開日2010-09-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.805 Å)
主引用文献Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
2Y35
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Crystal structure of Xrn1-substrate complex
分子名称: DT11 (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP)-3', LD22664P, MAGNESIUM ION
著者Jinek, M, Coyle, S.M, Doudna, J.A.
登録日2010-12-18
公開日2011-03-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Coupled 5' Nucleotide Recognition and Processivity in Xrn1-Mediated Mrna Decay.
Mol.Cell, 41, 2011
2XLJ
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Crystal structure of the Csy4-crRNA complex, hexagonal form
分子名称: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A.
登録日2010-07-20
公開日2010-09-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
2XLI
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Crystal structure of the Csy4-crRNA complex, monoclinic form
分子名称: 5'-R(*CP*UP*GP*CP*CP*GP*UP*AP*UP*AP*GP*GP*CP*A*DG*C)-3', CSY4 ENDORIBONUCLEASE
著者Haurwitz, R.E, Jinek, M, Wiedenheft, B, Zhou, K, Doudna, J.A.
登録日2010-07-20
公開日2010-09-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Sequence- and Structure-Specific RNA Processing by a Crispr Endonuclease.
Science, 329, 2010
3P2Q
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BU of 3p2q by Molmil
Crystal structure of the fluoroacetyl-CoA-specific thioesterase, FlK
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-03
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P3F
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Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P3I
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BU of 3p3i by Molmil
Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate and CoA
分子名称: COENZYME A, Fluoroacetyl coenzyme A thioesterase, fluoroacetic acid
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P2S
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Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in an open conformation
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P2R
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BU of 3p2r by Molmil
Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate
分子名称: Fluoroacetyl coenzyme A thioesterase, fluoroacetic acid
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-03
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
4OGC
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BU of 4ogc by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
分子名称: ACETATE ION, HNH endonuclease domain protein, MAGNESIUM ION, ...
著者Jiang, F, Ma, E, Lin, S, Doudna, J.A.
登録日2014-01-15
公開日2014-02-12
最終更新日2014-03-26
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
4OGE
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BU of 4oge by Molmil
Crystal structure of the Type II-C Cas9 enzyme from Actinomyces naeslundii
分子名称: HNH endonuclease domain protein, MAGNESIUM ION, SPERMIDINE, ...
著者Jiang, F, Ma, E, Lin, S, Doudna, J.A.
登録日2014-01-15
公開日2014-02-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献Structures of Cas9 endonucleases reveal RNA-mediated conformational activation.
Science, 343, 2014
4P6I
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BU of 4p6i by Molmil
Crystal structure of the Cas1-Cas2 complex from Escherichia coli
分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2
著者Nunez, J.K, Kranzusch, P.J, Noeske, J, Doudna, J.A.
登録日2014-03-24
公開日2014-05-07
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity.
Nat.Struct.Mol.Biol., 21, 2014
4PR6
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A Second Look at the HDV Ribozyme Structure and Dynamics.
分子名称: HDV RIBOZYME SELF-CLEAVED, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A
著者Kapral, G.J, Jain, S, Noeske, J, Doudna, J.A, Richardson, D.C, Richardson, J.S.
登録日2014-03-05
公開日2014-10-29
最終更新日2014-11-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献New tools provide a second look at HDV ribozyme structure, dynamics and cleavage.
Nucleic Acids Res., 42, 2014
4PRF
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BU of 4prf by Molmil
A Second Look at the HDV Ribozyme Structure and Dynamics.
分子名称: Hepatitis Delta virus ribozyme, STRONTIUM ION, U1 small nuclear ribonucleoprotein A
著者Kapral, G.J, Jain, S, Noeske, J, Doudna, J.A, Richardson, D.C, Richardson, J.S.
登録日2014-03-05
公開日2014-10-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.395 Å)
主引用文献New tools provide a second look at HDV ribozyme structure, dynamics and cleavage.
Nucleic Acids Res., 42, 2014
4C9D
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BU of 4c9d by Molmil
Cas6 (TTHB231) product complex
分子名称: CAS6B, R3 REPEAT RNA CLEAVAGE PRODUCT
著者Jinek, M, Niewoehner, O, Doudna, J.A.
登録日2013-10-02
公開日2013-11-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.
Nucleic Acids Res., 42, 2014
4C8Y
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BU of 4c8y by Molmil
Cas6 (TTHA0078) substrate mimic complex
分子名称: CAS6A, R1 REPEAT RNA SUBSTRATE MIMIC, SULFATE ION
著者Jinek, M, Niewoehner, O, Doudna, J.A.
登録日2013-10-02
公開日2013-11-06
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
4C98
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Thermus thermophilus Cas6 (TTHB231)
分子名称: CAS6B, ZINC ION
著者Jinek, M, Niewoehner, O, Doudna, J.A.
登録日2013-10-02
公開日2013-11-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014
4CMQ
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BU of 4cmq by Molmil
Crystal structure of Mn-bound S.pyogenes Cas9
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MANGANESE (II) ION, SULFATE ION
著者Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
登録日2014-01-17
公開日2014-02-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Structures of Cas9 Endonucleases Reveal RNA- Mediated Conformational Activation
Science, 343, 2014
4CMP
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Crystal structure of S. pyogenes Cas9
分子名称: CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION
著者Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A.
登録日2014-01-16
公開日2014-02-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
4C97
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Cas6 (TTHA0078) H37A mutant
分子名称: CAS6A, SULFATE ION
著者Jinek, M, Niewoehner, O, Doudna, J.A.
登録日2013-10-02
公開日2013-11-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
Nucleic Acids Res., 42, 2014

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