3P3I

Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate and CoA

Summary for 3P3I

Entry DOI	10.2210/pdb3p3i/pdb
Related	3P2Q 3P2R 3P2S 3P3F
Descriptor	Fluoroacetyl coenzyme A thioesterase, fluoroacetic acid, COENZYME A, ... (4 entities in total)
Functional Keywords	hot dog-fold, thioesterase, hydrolase
Biological source	Streptomyces cattleya
Total number of polymer chains	6
Total formula weight	94628.90
Authors	Weeks, A.M.,Coyle, S.M.,Jinek, M.,Doudna, J.A.,Chang, M.C.Y. (deposition date: 2010-10-04, release date: 2010-10-20, Last modification date: 2011-11-16)
Primary citation	Weeks, A.M.,Coyle, S.M.,Jinek, M.,Doudna, J.A.,Chang, M.C. Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity. Biochemistry, 49:9269-9279, 2010 Cited by PubMed: 20836570 DOI: 10.1021/bi101102u PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation