3P3I
Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate and CoA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016289 | molecular_function | acyl-CoA hydrolase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0016289 | molecular_function | acyl-CoA hydrolase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| C | 0016289 | molecular_function | acyl-CoA hydrolase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0042803 | molecular_function | protein homodimerization activity |
| D | 0016289 | molecular_function | acyl-CoA hydrolase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0042803 | molecular_function | protein homodimerization activity |
| E | 0016289 | molecular_function | acyl-CoA hydrolase activity |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0042803 | molecular_function | protein homodimerization activity |
| F | 0016289 | molecular_function | acyl-CoA hydrolase activity |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FAH A 140 |
| Chain | Residue |
| A | GLU50 |
| A | LEU68 |
| A | GLY69 |
| A | ARG120 |
| B | VAL23 |
| B | THR42 |
| B | COA140 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE COA B 140 |
| Chain | Residue |
| B | HIS76 |
| B | THR77 |
| B | HOH257 |
| A | GLY69 |
| A | FAH140 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FAH C 140 |
| Chain | Residue |
| C | GLU50 |
| C | LEU68 |
| C | GLY69 |
| C | ARG120 |
| C | HOH271 |
| D | THR42 |
| D | COA140 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE COA D 140 |
| Chain | Residue |
| C | LEU68 |
| C | GLY69 |
| C | THR70 |
| C | FAH140 |
| D | HIS76 |
| D | THR77 |
| D | ALA78 |
| D | ALA79 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Active site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 66 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20430898","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20836570","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
