1TDH
| Crystal structure of human endonuclease VIII-like 1 (NEIL1) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, nei endonuclease VIII-like 1 | Authors: | Doublie, S, Bandaru, V, Bond, J.P, Wallace, S.S. | Deposit date: | 2004-05-22 | Release date: | 2004-07-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of human endonuclease VIII-like 1 (NEIL1) reveals a zincless finger motif required for glycosylase activity. Proc.Natl.Acad.Sci.USA, 101, 2004
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1T7P
| T7 DNA POLYMERASE COMPLEXED TO DNA PRIMER/TEMPLATE,A NUCLEOSIDE TRIPHOSPHATE, AND ITS PROCESSIVITY FACTOR THIOREDOXIN | Descriptor: | 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*CP*TP*TP*GP*GP*CP*AP*CP*TP*GP*GP*C)-3'), DNA (5'-D(P*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*2DA)-3'), ... | Authors: | Doublie, S, Tabor, S, Long, A.M, Richardson, C.C, Ellenberger, T. | Deposit date: | 1997-09-24 | Release date: | 1998-02-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution. Nature, 391, 1998
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3W0F
| Crystal structure of mouse Endonuclease VIII-LIKE 3 (mNEIL3) | Descriptor: | Endonuclease 8-like 3, IODIDE ION, ZINC ION | Authors: | Liu, M, Imamura, K, Averill, A.M, Wallace, S.S, Doublie, S. | Deposit date: | 2012-10-30 | Release date: | 2013-01-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Characterization of a Mouse Ortholog of Human NEIL3 with a Marked Preference for Single-Stranded DNA Structure, 21, 2013
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4PPX
| DNA Polymerase Beta E295K with Spiroiminodihydantoin in Templating Position | Descriptor: | 5'-D(*CP*CP*GP*AP*CP*(SDH)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*G)-3', ... | Authors: | Eckenroth, B.E, Doublie, S. | Deposit date: | 2014-02-27 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Crystal Structure of DNA Polymerase beta with DNA Containing the Base Lesion Spiroiminodihydantoin in a Templating Position. Biochemistry, 53, 2014
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8TH9
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8SYJ
| Structure of apurinic/apyrimidinic DNA lyase TK0353 from Thermococcus kodakarensis (Iodide crystal form) | Descriptor: | GLYCEROL, IODIDE ION, SULFATE ION, ... | Authors: | Eckenroth, B.E, Gardner, A.F, Doublie, S. | Deposit date: | 2023-05-25 | Release date: | 2023-12-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Thermococcus kodakarensis TK0353 is a novel AP lyase with a new fold. J.Biol.Chem., 300, 2023
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8GM7
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8GM6
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6MW4
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7RDS
| Structure of human NTHL1 | Descriptor: | IRON/SULFUR CLUSTER, Isoform 3 of Endonuclease III-like protein 1 | Authors: | Carroll, B.L, Zahn, K.E, Doublie, S. | Deposit date: | 2021-07-11 | Release date: | 2021-12-29 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis. Nucleic Acids Res., 49, 2021
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7RDT
| Structure of human NTHL1 - linker 1 chimera | Descriptor: | IRON/SULFUR CLUSTER, Isoform 3 of Endonuclease III-like protein 1 | Authors: | Carroll, B.L, Doublie, S. | Deposit date: | 2021-07-11 | Release date: | 2021-12-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Caught in motion: human NTHL1 undergoes interdomain rearrangement necessary for catalysis. Nucleic Acids Res., 49, 2021
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4X0P
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6VJI
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6BTF
| DNA Polymerase Beta I260Q Ternary Complex | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA Downstream Strand, DNA Primer Strand, ... | Authors: | Eckenroth, B.E, Doublie, S. | Deposit date: | 2017-12-06 | Release date: | 2018-09-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Res., 46, 2018
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6BTE
| DNA Polymerase Beta I260Q Binary Complex | Descriptor: | CHLORIDE ION, DNA Downstream Strand, DNA Primer Strand, ... | Authors: | Eckenroth, B.E, Doublie, S. | Deposit date: | 2017-12-06 | Release date: | 2018-09-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | I260Q DNA polymerase beta highlights precatalytic conformational rearrangements critical for fidelity. Nucleic Acids Res., 46, 2018
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4X0Q
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1F5A
| CRYSTAL STRUCTURE OF MAMMALIAN POLY(A) POLYMERASE | Descriptor: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, POLY(A) POLYMERASE, ... | Authors: | Martin, G, Keller, W, Doublie, S. | Deposit date: | 2000-06-13 | Release date: | 2000-09-13 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP. EMBO J., 19, 2000
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7RAG
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2DTU
| Crystal structure of the beta hairpin loop deletion variant of RB69 gp43 in complex with DNA containing an abasic site analog | Descriptor: | 5'-D(*CP*GP*(3DR)P*CP*TP*TP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*AP*AP*GP*A)-3', DNA polymerase | Authors: | Aller, P, Hogg, M, Konigsberg, W, Wallace, S.S, Doublie, S. | Deposit date: | 2006-07-15 | Release date: | 2006-12-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structural and biochemical investigation of the role in proofreading of a beta hairpin loop found in the exonuclease domain of a replicative DNA polymerase of the B family. J.Biol.Chem., 282, 2007
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2DY4
| Crystal structure of RB69 GP43 in complex with DNA containing Thymine Glycol | Descriptor: | 5'-D(*CP*GP*(CTG)P*GP*GP*AP*AP*TP*GP*A*CP*AP*GP*CP*CP*GP*CP*G)-3', 5'-D(*GP*CP*GP*GP*CP*TP*GP*T*CP*AP*TP*TP*CP*CP*A)-3', DNA polymerase | Authors: | Aller, P, Rould, M.A, Hogg, M, Wallace, S.S, Doublie, S. | Deposit date: | 2006-09-06 | Release date: | 2007-01-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | A structural rationale for stalling of a replicative DNA polymerase at the most common oxidative thymine lesion, thymine glycol. Proc.Natl.Acad.Sci.USA, 104, 2007
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4KGM
| Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein in complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Hyde, S.J, Rao, B.S, Eckenroth, B.E, Jackman, J.E, Doublie, S. | Deposit date: | 2013-04-29 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.361 Å) | Cite: | Structural Studies of a Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein, with Nucleotide in the Activation and Nucleotidyl Transfer Sites. Plos One, 8, 2013
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4KGK
| Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein in complex with GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Thg1-like uncharacterized protein | Authors: | Hyde, S.J, Rao, B.S, Eckenroth, B.E, Jackman, J.E, Doublie, S. | Deposit date: | 2013-04-29 | Release date: | 2013-08-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural Studies of a Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein, with Nucleotide in the Activation and Nucleotidyl Transfer Sites. Plos One, 8, 2013
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1Z7N
| ATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis with bound PRPP substrate | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, ATP phosphoribosyltransferase, ATP phosphoribosyltransferase regulatory subunit, ... | Authors: | Champagne, K.S, Sissler, M, Larrabee, Y, Doublie, S, Francklyn, C.S. | Deposit date: | 2005-03-25 | Release date: | 2005-08-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Activation of the hetero-octameric ATP phosphoribosyl transferase through subunit interface rearrangement by a tRNA synthetase paralog. J.Biol.Chem., 280, 2005
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1Z7M
| ATP Phosphoribosyl transferase (HisZG ATP-PRTase) from Lactococcus lactis | Descriptor: | ATP phosphoribosyltransferase, ATP phosphoribosyltransferase regulatory subunit, PHOSPHATE ION, ... | Authors: | Champagne, K.S, Sissler, M, Larrabee, Y, Doublie, S, Francklyn, C.S. | Deposit date: | 2005-03-25 | Release date: | 2005-08-09 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Activation of the hetero-octameric ATP phosphoribosyl transferase through subunit interface rearrangement by a tRNA synthetase paralog. J.Biol.Chem., 280, 2005
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4I0W
| Structure of the Clostridium Perfringens CspB protease | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Protease CspB, ... | Authors: | Adams, C.M, Eckenroth, B.E, Doublie, S. | Deposit date: | 2012-11-19 | Release date: | 2013-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and functional analysis of the CspB protease required for Clostridium spore germination. Plos Pathog., 9, 2013
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