4PPX
DNA Polymerase Beta E295K with Spiroiminodihydantoin in Templating Position
Summary for 4PPX
Entry DOI | 10.2210/pdb4ppx/pdb |
Descriptor | DNA polymerase beta, 5'-D(*CP*CP*GP*AP*CP*(SDH)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', ... (6 entities in total) |
Functional Keywords | dna polymerase, dna complex, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P06746 |
Total number of polymer chains | 4 |
Total formula weight | 47787.93 |
Authors | Eckenroth, B.E.,Doublie, S. (deposition date: 2014-02-27, release date: 2014-04-02, Last modification date: 2023-09-20) |
Primary citation | Eckenroth, B.E.,Fleming, A.M.,Sweasy, J.B.,Burrows, C.J.,Doublie, S. Crystal Structure of DNA Polymerase beta with DNA Containing the Base Lesion Spiroiminodihydantoin in a Templating Position. Biochemistry, 53:2075-2077, 2014 Cited by PubMed: 24649945DOI: 10.1021/bi500270e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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