Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 163 件
5WEQ
DownloadVisualize
BU of 5weq by Molmil
The crystal structure of a MR78 mutant
分子名称: MR78 mutant Fab heavy chain, MR78 mutant light chain
著者Dong, J, Williamson, L.E, Crowe, J.E.
登録日2017-07-10
公開日2018-04-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein.
Structure, 25, 2017
5E0R
DownloadVisualize
BU of 5e0r by Molmil
Crystal Structure of the first bromodomain of BRD4 in complex with AYC
分子名称: 2-[(chloroacetyl)amino]-5-[(E)-(4-sulfophenyl)diazenyl]benzenesulfonic acid, Bromodomain-containing protein 4, DIMETHYL SULFOXIDE
著者Dong, J, Caflisch, A.
登録日2015-09-29
公開日2016-10-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.352 Å)
主引用文献Crystal Structure of the first bromodomain of BRD4 in complex with AYC
To Be Published
5F3A
DownloadVisualize
BU of 5f3a by Molmil
Crystal structure of the bromodomain of human ATAD2 in complex with Compound A14
分子名称: ATPase family AAA domain-containing protein 2, SULFATE ION, ~{N}-(4-ethanoyl-1,3-thiazol-2-yl)azetidin-1-ium-3-carboxamide
著者Dong, J, Caflisch, A.
登録日2015-12-02
公開日2016-12-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Crystal structure of the bromodomain of human ATAD2 in complex with Compound A14
To Be Published
5F36
DownloadVisualize
BU of 5f36 by Molmil
Crystal structure of the bromodomain of human ATAD2 in complex with Compound A12
分子名称: ATPase family AAA domain-containing protein 2, CHLORIDE ION, SULFATE ION, ...
著者Dong, J, Caflisch, A.
登録日2015-12-02
公開日2016-12-14
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.
Acs Med.Chem.Lett., 11, 2020
5EPB
DownloadVisualize
BU of 5epb by Molmil
Crystal structure of the bromodomain of human ATAD2 in complex with Compound 49
分子名称: ATPase family AAA domain-containing protein 2, SULFATE ION, ~{N}-[(2~{S})-2-morpholin-4-ylpropyl]-4-oxidanylidene-3,5-dihydro-2~{H}-1,5-benzothiazepine-7-carboxamide
著者Dong, J, Caflisch, A.
登録日2015-11-11
公開日2016-11-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the bromodomain of human ATAD2 in complex with Compound 49
To Be Published
5D1I
DownloadVisualize
BU of 5d1i by Molmil
Structure of Cyclic nucleotide-binding-like protein from Brucella abortus bv. 1 str. 9-941
分子名称: Cyclic nucleotide-binding protein
著者He, Z, Dong, J, Li, X, Gao, Y.
登録日2015-08-04
公開日2015-09-09
最終更新日2016-01-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of cyclic nucleotide-binding-like protein from Brucella abortus
Biochem.Biophys.Res.Commun., 468, 2015
8JBW
DownloadVisualize
BU of 8jbw by Molmil
Crystal structure of ZtHPPD-(+)-Usnic acid complex
分子名称: (9bR)-2,6-diethanoyl-8,9b-dimethyl-3,7,9-tris(oxidanyl)dibenzofuran-1-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
著者Lin, H.-Y, Dong, J, Yang, G.-F.
登録日2023-05-09
公開日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Discovery and Development of 4-Hydroxyphenylpyruvate Dioxygenase as a Novel Crop Fungicide Target.
J.Agric.Food Chem., 71, 2023
8J8X
DownloadVisualize
BU of 8j8x by Molmil
Crystal structure of AtHPPD-YH20307 complex
分子名称: 4-hydroxyphenylpyruvate dioxygenase, 5-(1,3-dimethyl-5-oxidanyl-pyrazol-4-yl)carbonyl-1,4-dimethyl-3-propan-2-yl-benzimidazol-2-one, COBALT (II) ION
著者Lin, H.-Y, Dong, J, Yang, G.-F.
登録日2023-05-02
公開日2024-05-08
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Crystal structure of AtHPPD-YH20307 complex
To Be Published
8J8W
DownloadVisualize
BU of 8j8w by Molmil
Crystal structure of AtHPPD-Y19788 complex
分子名称: 2,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-phenyl-quinazolin-4-one, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
著者Lin, H.-Y, Dong, J, Yang, G.-F.
登録日2023-05-02
公開日2024-05-08
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Crystal structure of AtHPPD-Y19788 complex
To Be Published
8K0B
DownloadVisualize
BU of 8k0b by Molmil
Cryo-EM structure of TMEM63C
分子名称: Calcium permeable stress-gated cation channel 1
著者Qin, Y, Yu, D, Dong, J, Dang, S.
登録日2023-07-08
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Cryo-EM structure of TMEM63C suggests it functions as a monomer.
Nat Commun, 14, 2023
1XF7
DownloadVisualize
BU of 1xf7 by Molmil
High Resolution NMR Structure of the Wilms' Tumor Suppressor Protein (WT1) Finger 3
分子名称: Wilms' Tumor Protein, ZINC ION
著者Lachenmann, M.J, Ladbury, J.E, Dong, J, Huang, K, Carey, P, Weiss, M.A.
登録日2004-09-14
公開日2004-12-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Why zinc fingers prefer zinc: ligand-field symmetry and the hidden thermodynamics of metal ion selectivity
Biochemistry, 43, 2004
8HOW
DownloadVisualize
BU of 8how by Molmil
Crystal structure of AtHPPD-Y191052 complex
分子名称: 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(2-phenylethyl)quinazoline-2,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
著者Yang, G.-F, Lin, H.-Y, Dong, J.
登録日2022-12-11
公開日2023-01-25
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Discovery of Subnanomolar Inhibitors of 4-Hydroxyphenylpyruvate Dioxygenase via Structure-Based Rational Design.
J.Agric.Food Chem., 71, 2023
8WQM
DownloadVisualize
BU of 8wqm by Molmil
Complex structure of AtHPPD with Atovaquone
分子名称: 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION
著者Yang, G.-F, Lin, H.-Y, Dong, J.
登録日2023-10-11
公開日2024-03-13
最終更新日2024-04-17
実験手法X-RAY DIFFRACTION (1.796 Å)
主引用文献Complex structure of AtHPPD with Atovaquone
To Be Published
1OMZ
DownloadVisualize
BU of 1omz by Molmil
crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) in complex with UDPGalNAc
分子名称: 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, ...
著者Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M.
登録日2003-02-26
公開日2003-04-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
1OMX
DownloadVisualize
BU of 1omx by Molmil
Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2)
分子名称: 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2
著者Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M.
登録日2003-02-26
公開日2003-04-22
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
1ON6
DownloadVisualize
BU of 1on6 by Molmil
Crystal structure of mouse alpha-1,4-N-acetylhexosaminotransferase (EXTL2) in complex with UDPGlcNAc
分子名称: 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, ...
著者Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M.
登録日2003-02-27
公開日2003-04-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
1ON8
DownloadVisualize
BU of 1on8 by Molmil
Crystal structure of mouse alpha-1,4-N-acetylhexosaminyltransferase (EXTL2) with UDP and GlcUAb(1-3)Galb(1-O)-naphthalenelmethanol an acceptor substrate analog
分子名称: 1,2-ETHANEDIOL, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, MANGANESE (II) ION, ...
著者Pedersen, L.C, Dong, J, Taniguchi, F, Kitagawa, H, Krahn, J.M, Pedersen, L.G, Sugahara, K, Negishi, M.
登録日2003-02-27
公開日2003-04-22
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of an alpha-1,4-N-acetylhexosaminyltransferase (EXTL2), a member of the exostosin gene family involved in heparan sulfate biosynthesis
J.Biol.Chem., 278, 2003
6TTI
DownloadVisualize
BU of 6tti by Molmil
PKM2 in complex with Compound 6
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, DIMETHYL SULFOXIDE, Pyruvate kinase PKM, ...
著者Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
登録日2019-12-27
公開日2020-01-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6U07
DownloadVisualize
BU of 6u07 by Molmil
Computational Stabilization of T Cell Receptor Constant Domains
分子名称: MAGNESIUM ION, Stabilized T cell receptor constant domain (Calpha), Stabilized T cell receptor constant domain (Cbeta)
著者Froning, K, Maguire, J, Sereno, A, Huang, F, Chang, S, Weichert, K, Frommelt, A.J, Dong, J, Wu, X, Austin, H, Conner, E.M, Fitchett, J.R, Heng, A.R, Balasubramaniam, D, Hilgers, M.T, Kuhlman, B, Demarest, S.J.
登録日2019-08-13
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Computational stabilization of T cell receptors allows pairing with antibodies to form bispecifics.
Nat Commun, 11, 2020
6TSH
DownloadVisualize
BU of 6tsh by Molmil
Beta-galactosidase in complex with deoxygalacto-nojirimycin
分子名称: (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, Beta-galactosidase, MAGNESIUM ION
著者Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
登録日2019-12-20
公開日2020-01-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6TTH
DownloadVisualize
BU of 6tth by Molmil
PKM2 in complex with L-threonine
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, Pyruvate kinase PKM, THREONINE
著者Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
登録日2019-12-27
公開日2020-01-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6TTQ
DownloadVisualize
BU of 6ttq by Molmil
PKM2 in complex with Compound 10
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 1-propan-2-yl-3-pyridin-4-yl-urea, Pyruvate kinase PKM
著者Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
登録日2019-12-30
公開日2020-01-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6TTE
DownloadVisualize
BU of 6tte by Molmil
Beta-galactosidase in complex with PETG
分子名称: 2-phenylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, MAGNESIUM ION
著者Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
登録日2019-12-27
公開日2020-01-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6TSK
DownloadVisualize
BU of 6tsk by Molmil
Beta-galactosidase in complex with L-ribose
分子名称: Beta-galactosidase, MAGNESIUM ION, beta-L-ribopyranose
著者Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
登録日2019-12-20
公開日2020-01-08
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020
6TTF
DownloadVisualize
BU of 6ttf by Molmil
PKM2 in complex with Compound 5
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 5-hydroxynaphthalene-1-sulfonamide, Pyruvate kinase PKM
著者Saur, M, Hartshorn, M.J, Dong, J, Reeks, J, Bunkoczi, G, Jhoti, H, Williams, P.A.
登録日2019-12-27
公開日2020-01-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Fragment-based drug discovery using cryo-EM.
Drug Discov Today, 25, 2020

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon