Summary for 8HOW
| Entry DOI | 10.2210/pdb8how/pdb |
| Descriptor | 4-hydroxyphenylpyruvate dioxygenase, COBALT (II) ION, 1,5-dimethyl-6-(2-oxidanyl-6-oxidanylidene-cyclohexen-1-yl)carbonyl-3-(2-phenylethyl)quinazoline-2,4-dione, ... (4 entities in total) |
| Functional Keywords | complex, inhibitor, oxidoreductase |
| Biological source | Arabidopsis thaliana (thale cress) |
| Total number of polymer chains | 1 |
| Total formula weight | 46444.13 |
| Authors | Yang, G.-F.,Lin, H.-Y.,Dong, J. (deposition date: 2022-12-11, release date: 2023-01-25, Last modification date: 2023-02-01) |
| Primary citation | Dong, J.,Dong, J.,Yu, X.H.,Yan, Y.C.,Nan, J.X.,Ye, B.Q.,Yang, W.C.,Lin, H.Y.,Yang, G.F. Discovery of Subnanomolar Inhibitors of 4-Hydroxyphenylpyruvate Dioxygenase via Structure-Based Rational Design. J.Agric.Food Chem., 71:1170-1177, 2023 Cited by PubMed: 36599124DOI: 10.1021/acs.jafc.2c06727 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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