6ZMK
| Crystal structure of human GFAT-1 L405R | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Mayr, F, Miethe, S, Atanassov, I, Baumann, U, Denzel, M.S. | 登録日 | 2020-07-02 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun, 12, 2021
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6ZMJ
| Crystal structure of human GFAT-1 R203H | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Mayr, F, Miethe, S, Atanassov, I, Baumann, U, Denzel, M.S. | 登録日 | 2020-07-02 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.774 Å) | 主引用文献 | Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun, 12, 2021
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7NUU
| Crystal structure of human AMDHD2 in complex with Zn | 分子名称: | GLYCEROL, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION | 著者 | Ruegenberg, S, Kroef, V, Baumann, U, Denzel, M.S. | 登録日 | 2021-03-14 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.836 Å) | 主引用文献 | GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. Elife, 11, 2022
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7NUT
| Crystal structure of human AMDHD2 in complex with Zn and GlcN6P | 分子名称: | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, N-acetylglucosamine-6-phosphate deacetylase, ZINC ION | 著者 | Ruegenberg, S, Kroef, V, Baumann, U, Denzel, M.S. | 登録日 | 2021-03-14 | 公開日 | 2021-04-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.898 Å) | 主引用文献 | GFPT2/GFAT2 and AMDHD2 act in tandem to control the hexosamine pathway. Elife, 11, 2022
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6R4F
| Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate | 分子名称: | GLUCOSE-6-PHOSPHATE, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-03-22 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6R4G
| Crystal structure of human GFAT-1 in complex with UDP-GlcNAc | 分子名称: | GLUCOSE-6-PHOSPHATE, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, MAGNESIUM ION, ... | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-03-22 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6R4J
| Crystal structure of human GFAT-1 G451E in complex with UDP-GlcNAc | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, ... | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-03-22 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6R4E
| Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate and L-Glu | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-03-22 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6R4H
| Crystal structure of human GFAT-1 G451E | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-03-22 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.244 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6R4I
| Crystal structure of human GFAT-1 G461E | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-03-22 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.586 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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7NDL
| Crystal structure of human GFAT-1 S205D | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Isoform 2 of Glutamine-fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Baumann, U, Denzel, M.S. | 登録日 | 2021-02-02 | 公開日 | 2021-03-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.223 Å) | 主引用文献 | Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun, 12, 2021
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6SVP
| Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate, L-Glu, and UDP-GlcNAc | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, ... | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-09-18 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.531 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6SVM
| Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate, L-Glu, and UDP-GalNAc | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, ... | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-09-18 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.481 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6SVQ
| Crystal structure of human GFAT-1 G461E after UDP-GlcNAc soaking | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate-aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-09-18 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.717 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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6SVO
| Crystal structure of human GFAT-1 in complex with Glucosamine-6-Phosphate and L-Glu | 分子名称: | 2-DEOXY-2-AMINO GLUCITOL-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Horn, M, Pichlo, C, Allmeroth, K, Baumann, U, Denzel, M.S. | 登録日 | 2019-09-18 | 公開日 | 2020-01-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.328 Å) | 主引用文献 | Loss of GFAT-1 feedback regulation activates the hexosamine pathway that modulates protein homeostasis. Nat Commun, 11, 2020
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