6ZMJ

Crystal structure of human GFAT-1 R203H

Summary for 6ZMJ

Entry DOI	10.2210/pdb6zmj/pdb
Descriptor	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, ... (4 entities in total)
Functional Keywords	glutamine fructose-6-phosphate amidotransferase, gfat, ntn hydrolase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	156021.32
Authors	Ruegenberg, S.,Mayr, F.,Miethe, S.,Atanassov, I.,Baumann, U.,Denzel, M.S. (deposition date: 2020-07-02, release date: 2020-08-05, Last modification date: 2024-01-31)
Primary citation	Ruegenberg, S.,Mayr, F.A.M.C.,Atanassov, I.,Baumann, U.,Denzel, M.S. Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun, 12:2176-2176, 2021 Cited by PubMed: 33846315 DOI: 10.1038/s41467-021-22320-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.774 Å)

Structure validation