6CWA
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1B7E
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![BU of 1b7e by Molmil](/molmil-images/mine/1b7e) | TRANSPOSASE INHIBITOR | 分子名称: | 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride, PROTEIN (TRANSPOSASE INHIBITOR PROTEIN FROM TN5) | 著者 | Davies, D.R, Braam, L.M, Reznikoff, W.S, Rayment, I. | 登録日 | 1999-01-22 | 公開日 | 1999-04-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The three-dimensional structure of a Tn5 transposase-related protein determined to 2.9A resolution. J.Biol.Chem., 274, 1999
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6AUB
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6AUA
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7UE1
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![BU of 7ue1 by Molmil](/molmil-images/mine/7ue1) | HIV-1 Integrase Catalytic Core Domain Mutant (KGD) in Complex with Inhibitor GRL-142 | 分子名称: | (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate, Integrase, SULFATE ION | 著者 | Aoki, M, Aoki-Ogata, H, Bulut, H, Hayashi, H, Davis, D, Hasegawa, K, Yarchoan, R, Ghosh, A.K, Pau, A.K, Mitsuya, H. | 登録日 | 2022-03-21 | 公開日 | 2023-03-22 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | GRL-142 binds to and impairs HIV-1 integrase nuclear localization signal and potently suppresses highly INSTI-resistant HIV-1 variants. Sci Adv, 9, 2023
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4AUA
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![BU of 4aua by Molmil](/molmil-images/mine/4aua) | Liganded X-ray crystal structure of cyclin dependent kinase 6 (CDK6) | 分子名称: | 1H-benzimidazol-2-yl(1H-pyrrol-2-yl)methanone, CYCLIN-DEPENDENT KINASE 6 | 著者 | Cho, Y.S, Angove, H, Brain, C, Chen, C.H.T, Cheng, R, Chopra, R, Chung, K, Congreve, M, Dagostin, C, Davis, D, Feltell, R, Giraldes, J, Hiscock, S, Kim, S, Kovats, S, Lagu, B, Lewry, K, Loo, A, Lu, Y, Luzzio, M, Maniara, W, Mcmenamin, R, Mortenson, P, Benning, R, O'Reilly, M, Rees, D, Shen, J, Smith, T, Wang, Y, Williams, G, Woolford, A, Wrona, W, Xu, M, Yang, F, Howard, S. | 登録日 | 2012-05-15 | 公開日 | 2013-02-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors. ACS Med Chem Lett, 3, 2012
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3T0Q
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![BU of 3t0q by Molmil](/molmil-images/mine/3t0q) | Motor Domain Structure of the Kar3-like kinesin from Ashbya gossypii | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, AGR253Wp, ... | 著者 | Duan, D, Hnatchuk, D.J, Brenner, J, Davis, D, Allingham, J.S. | 登録日 | 2011-07-20 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Crystal structure of the Kar3-like kinesin motor domain from the filamentous fungus Ashbya gossypii. Proteins, 80, 2012
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1Q5W
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![BU of 1q5w by Molmil](/molmil-images/mine/1q5w) | Ubiquitin Recognition by Npl4 Zinc-Fingers | 分子名称: | Ubiquitin, ZINC ION, homolog of yeast nuclear protein localization 4 | 著者 | Alam, S.L, Sun, J, Payne, M, Welch, B.D, Blake, B.K, Davis, D.R, Meyer, H.H, Emr, S.D, Sundquist, W.I. | 登録日 | 2003-08-11 | 公開日 | 2004-03-30 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Ubiquitin interactions of NZF zinc fingers. Embo J., 23, 2004
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1FL8
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1NJ3
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![BU of 1nj3 by Molmil](/molmil-images/mine/1nj3) | Structure and Ubiquitin Interactions of the Conserved NZF Domain of Npl4 | 分子名称: | NPL4, ZINC ION | 著者 | Wang, B, Alam, S.L, Meyer, H.H, Payne, M, Stemmler, T.L, Davis, D.R, Sundquist, W.I. | 登録日 | 2002-12-30 | 公開日 | 2003-04-22 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and ubiquitin interactions of the conserved zinc finger domain of Npl4. J.Biol.Chem., 278, 2003
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1KPQ
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![BU of 1kpq by Molmil](/molmil-images/mine/1kpq) | Structure of the Tsg101 UEV domain | 分子名称: | Tumor susceptibility gene 101 protein | 著者 | Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I. | 登録日 | 2002-01-02 | 公開日 | 2002-05-25 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and functional interactions of the Tsg101 UEV domain. EMBO J., 21, 2002
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1KPP
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![BU of 1kpp by Molmil](/molmil-images/mine/1kpp) | Structure of the Tsg101 UEV domain | 分子名称: | Tumor susceptibility gene 101 protein | 著者 | Pornillos, O, Alam, S.L, Rich, R.L, Myszka, D.G, Davis, D.R, Sundquist, W.I. | 登録日 | 2002-01-02 | 公開日 | 2002-05-24 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and functional interactions of the Tsg101 UEV domain. EMBO J., 21, 2002
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2BU1
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![BU of 2bu1 by Molmil](/molmil-images/mine/2bu1) | MS2-RNA HAIRPIN (5BRU -5) COMPLEX | 分子名称: | 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *5BU*AP*CP*CP*CP*AP*UP*GP*U)-3', MS2 COAT PROTEIN | 著者 | Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L. | 登録日 | 2005-06-08 | 公開日 | 2005-08-18 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. Rna, 7, 2001
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2C50
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![BU of 2c50 by Molmil](/molmil-images/mine/2c50) | MS2-RNA HAIRPIN (A -5) COMPLEX | 分子名称: | 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *AP*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN | 著者 | Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L. | 登録日 | 2005-10-25 | 公開日 | 2006-01-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. Rna, 7, 2001
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2C4Q
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![BU of 2c4q by Molmil](/molmil-images/mine/2c4q) | MS2-RNA HAIRPIN (2ONE -5) COMPLEX | 分子名称: | 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *PYO*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN | 著者 | Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L. | 登録日 | 2005-10-21 | 公開日 | 2005-11-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. Rna, 7, 2001
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2C51
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![BU of 2c51 by Molmil](/molmil-images/mine/2c51) | MS2-RNA HAIRPIN (G -5) COMPLEX | 分子名称: | 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *GP*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN | 著者 | Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L. | 登録日 | 2005-10-25 | 公開日 | 2006-01-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. Rna, 7, 2001
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2C4Y
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![BU of 2c4y by Molmil](/molmil-images/mine/2c4y) | MS2-RNA HAIRPIN (2THIOURACIL-5) COMPLEX | 分子名称: | 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*UP *SUR*AP*CP*CP*CP*AP*UP*GP*U)-3', Capsid protein | 著者 | Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L. | 登録日 | 2005-10-25 | 公開日 | 2006-01-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. Rna, 7, 2001
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2C4Z
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![BU of 2c4z by Molmil](/molmil-images/mine/2c4z) | MS2-RNA HAIRPIN (2SU -5-6) COMPLEX | 分子名称: | 5'-R(*AP*CP*AP*UP*GP*AP*GP*GP*AP*SUR *SUR*AP*CP*CP*CP*AP*UP*GP*U)-3', COAT PROTEIN | 著者 | Grahn, E, Moss, T, Helgstrand, C, Fridborg, K, Sundaram, M, Tars, K, Lago, H, Stonehouse, N.J, Davis, D.R, Stockley, P.G, Liljas, L. | 登録日 | 2005-10-25 | 公開日 | 2006-01-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of pyrimidine specificity in the MS2 RNA hairpin-coat-protein complex. Rna, 7, 2001
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2LPS
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1M4P
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![BU of 1m4p by Molmil](/molmil-images/mine/1m4p) | Structure of the Tsg101 UEV domain in complex with a HIV-1 PTAP "late domain" peptide, DYANA Ensemble | 分子名称: | Gag Polyprotein, Tumor Susceptibility gene 101 protein | 著者 | Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I. | 登録日 | 2002-07-03 | 公開日 | 2002-11-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein Nat.Struct.Biol., 9, 2002
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1M4Q
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![BU of 1m4q by Molmil](/molmil-images/mine/1m4q) | STRUCTURE OF THE TSG101 UEV DOMAIN IN COMPLEX WITH A HIV-1 PTAP "LATE DOMAIN" PEPTIDE, CNS ENSEMBLE | 分子名称: | Gag Polyprotein, Tumor Susceptibility gene 101 protein | 著者 | Pornillos, O, Alam, S.L, Davis, D.R, Sundquist, W.I. | 登録日 | 2002-07-03 | 公開日 | 2002-11-06 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Tsg101 UEV domain in complex with the PTAP motif of the HIV-1 p6 protein Nat.Struct.Biol., 9, 2002
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2KTZ
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![BU of 2ktz by Molmil](/molmil-images/mine/2ktz) | Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA | 分子名称: | (7R)-7-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazol-2-amine, HCV IRES Domain IIa RNA | 著者 | Paulsen, R.B, Seth, P.P, Swayze, E.E, Griffey, R.H, Skalicky, J.J, Cheatham III, T.E, Davis, D.R. | 登録日 | 2010-02-10 | 公開日 | 2010-04-28 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Inhibitor-induced structural change in the HCV IRES domain IIa RNA. Proc.Natl.Acad.Sci.USA, 107, 2010
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2KU0
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![BU of 2ku0 by Molmil](/molmil-images/mine/2ku0) | Inhibitor Induced Structural Change in the HCV IRES Domain IIa RNA | 分子名称: | (7S)-7-[(dimethylamino)methyl]-1-[3-(dimethylamino)propyl]-7,8-dihydro-1H-furo[3,2-e]benzimidazol-2-amine, HCV IRES Domain IIa RNA | 著者 | Paulsen, R.B, Seth, P.P, Swayze, E.E, Griffey, R.H, Skalicky, J.J, Cheatham III, T.E, Davis, D.R. | 登録日 | 2010-02-10 | 公開日 | 2010-04-28 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Inhibitor-induced structural change in the HCV IRES domain IIa RNA. Proc.Natl.Acad.Sci.USA, 107, 2010
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2LPT
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2VTL
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![BU of 2vtl by Molmil](/molmil-images/mine/2vtl) | Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H- pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design | 分子名称: | CELL DIVISION PROTEIN KINASE 2, N-phenyl-1H-pyrazole-3-carboxamide | 著者 | Wyatt, P.G, Woodhead, A.J, Boulstridge, J.A, Berdini, V, Carr, M.G, Cross, D.M, Danillon, D, Davis, D.J, Devine, L.A, Early, T.R, Feltell, R.E, Lewis, E.J, McMenamin, R.L, Navarro, E.F, O'Brien, M.A, O'Reilly, M, Reule, M, Saxty, G, Seavers, L.C.A, Smith, D, Squires, M.S, Trewartha, G, Walker, M.T, Woolford, A.J. | 登録日 | 2008-05-15 | 公開日 | 2008-08-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification of N-(4-Piperidinyl)-4-(2,6-Dichlorobenzoylamino)-1H-Pyrazole-3-Carboxamide (at7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design. J.Med.Chem., 51, 2008
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