6AUB

CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR CGI2815

Summary for 6AUB

• Entry DOI: 10.2210/pdb6aub/pdb
• Related: 6AUA
• Descriptor: Tyrosine-protein kinase BTK, SULFATE ION, 4-tert-butyl-N-[2-methyl-3-(1-methyl-5-{[5-(morpholine-4-carbonyl)pyridin-2-yl]amino}-6-oxo-1,6-dihydropyridin-3-yl)phenyl]benzamide, ... (4 entities in total)
• Functional Keywords: btk, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 31733.45

Authors

Davies, D.R.,Staker, B.L. (deposition date: 2017-08-31, release date: 2018-09-12, Last modification date: 2023-10-04)

• Primary citation: Ortwine, D.; To Be Determined; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (1.65 Å)