6AUA

CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR CGI2625

Summary for 6AUA

DescriptorTyrosine-protein kinase BTK, GLYCEROL, SULFATE ION, ... (5 entities in total)
Functional Keywordsbtk, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight31796.48
Authors
Davies, D.R.,Staker, B.L. (deposition date: 2017-08-31, release date: 2018-09-12)
Primary citation
Ortwine, D.
To Be Determined
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (1.66 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.185200.9%1.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6aua
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Molmil generated image of 6aua
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Molmil generated image of 6aua
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