9B1K
 
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9B1H
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9B1O
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9B1F
 | | Human urate transporter 1 URAT1 in apo state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Solute carrier family 22 member 12 | | 著者 | Dai, Y, Lee, C.H. | | 登録日 | 2024-03-13 | | 公開日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
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9B1G
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9B1I
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9B1N
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9B1J
 | | Urate bound human URAT1 in the inward-facing state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, Solute carrier family 22 member 12, ... | | 著者 | Dai, Y, Lee, C.H. | | 登録日 | 2024-03-13 | | 公開日 | 2024-09-18 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Transport mechanism and structural pharmacology of human urate transporter URAT1.
Cell Res., 2024
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9B1L
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9B1M
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8K5Q
 | | Crystal structure of YajQ STM0435 with c-di-GMP | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), YajQ | | 著者 | Dai, Y, Zhang, M, Wang, W, Li, B. | | 登録日 | 2023-07-23 | | 公開日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | A c-di-GMP binding effector STM0435 modulates flagellar motility and pathogenicity in Salmonella
Virulence, 15, 2024
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8K4I
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7E8I
 | | Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin | | 分子名称: | BRCA1-associated RING domain protein 1, DNA (145-MER), Histone H2A, ... | | 著者 | Dai, Y, Dai, L, Zhou, Z. | | 登録日 | 2021-03-01 | | 公開日 | 2021-06-30 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.
Mol.Cell, 81, 2021
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8IL0
 | | Crystal structure of LmbT from Streptomyces lincolnensis NRRL ISP-5355 | | 分子名称: | Glycosyltransferase | | 著者 | Dai, Y, Li, P, Qiao, H, Xia, M, Liu, W, Fang, P. | | 登録日 | 2023-03-01 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis.
Acs Chem.Biol., 18, 2023
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8ILA
 | | Crystal structure of LmbT from Streptomyces lincolnensis NRRL ISP-5355 in complex with substrates | | 分子名称: | (2~{S})-3-[2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-[(1~{R},2~{R})-1-azanyl-2-oxidanyl-propyl]-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanyl-1~{H}-imidazol-5-yl]-2-(trimethyl-$l^{4}-azanyl)propanoic acid, GUANOSINE-5'-DIPHOSPHATE, Glycosyltransferase | | 著者 | Dai, Y, Qiao, H, Xia, M, Fang, P, Liu, W. | | 登録日 | 2023-03-03 | | 公開日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural Basis of Low-Molecular-Weight Thiol Glycosylation in Lincomycin A Biosynthesis.
Acs Chem.Biol., 18, 2023
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7XBK
 | | Structure and mechanism of a mitochondrial AAA+ disaggregase CLPB | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Isoform 2 of Caseinolytic peptidase B protein homolog, MAGNESIUM ION, ... | | 著者 | Wu, D, Liu, Y, Dai, Y, Wang, G, Lu, G, Chen, Y, Li, N, Lin, J, Gao, N. | | 登録日 | 2022-03-21 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization.
Plos Biol., 21, 2023
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8SNN
 | | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 1 | | 分子名称: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2 | | 著者 | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | 登録日 | 2023-04-27 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.32 Å) | | 主引用文献 | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 1
To Be Published
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8SNM
 | | Structure of mature human ADAM17/iRhom2 sheddase complex in complex with ADAM17 prodomain | | 分子名称: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Disintegrin and metalloproteinase domain-containing protein 17 propeptide, ... | | 著者 | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | 登録日 | 2023-04-27 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.84 Å) | | 主引用文献 | Structure of mature human ADAM17/iRhom2 sheddase complex in complex with ADAM17 prodomain
To Be Published
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8SNO
 | | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 2 | | 分子名称: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2 | | 著者 | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | 登録日 | 2023-04-27 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Structure of mature human ADAM17/iRhom2 sheddase complex, conformation 2
To Be Published
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8SNL
 | | Structure of human ADAM17/iRhom2 sheddase complex | | 分子名称: | CALCIUM ION, Disintegrin and metalloproteinase domain-containing protein 17, Inactive rhomboid protein 2, ... | | 著者 | Zhao, H, Dai, Y, Wang, Y, Lee, C.H. | | 登録日 | 2023-04-27 | | 公開日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Structure of human ADAM17/iRhom2 sheddase complex
To Be Published
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8T6B
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8T69
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8T6A
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8EX5
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8EX6
 | | Human S1P transporter Spns2 in an inward-facing open conformation (state 1*) | | 分子名称: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Sphingosine-1-phosphate transporter SPNS2 | | 著者 | Ahmed, S, Zhao, H, Dai, Y, Lee, C.H. | | 登録日 | 2022-10-24 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate.
Cell, 186, 2023
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