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PDB: 1609 件

1Q46
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crystal structure of the eIF2 alpha subunit from saccharomyces cerevisia
分子名称: translation initiation factor 2 alpha subunit
著者Dhaliwal, S, Hoffman, D.W.
登録日2003-08-01
公開日2003-10-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献The crystal structure of the N-terminal region of the alpha subunit of translation initiation factor 2 (eIF2alpha) from Saccharomyces cerevisiae provides a view of the loop containing serine 51, the target of the eIF2alpha-specific kinases.
J.Mol.Biol., 334, 2003
1Q4R
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Gene Product of At3g17210 from Arabidopsis Thaliana
分子名称: MAGNESIUM ION, protein At3g17210
著者Phillips Jr, G.N, Bingman, C.A, Johnson, K.A, Smith, D.W, Center for Eukaryotic Structural Genomics (CESG)
登録日2003-08-04
公開日2003-11-25
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the protein from gene At3g17210 of Arabidopsis thaliana
Proteins, 57, 2004
1H4N
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H94N CARBONIC ANHYDRASE II COMPLEXED WITH TRIS
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CARBONIC ANHYDRASE II, ZINC ION
著者Lesburg, C.A, Christianson, D.W.
登録日1997-05-29
公開日1997-09-17
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Histidine --> carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity.
Biochemistry, 36, 1997
1HEB
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STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II
分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
著者Nair, S.K, Christianson, D.W.
登録日1992-07-16
公開日1992-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II.
Biochemistry, 32, 1993
1Q45
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12-0xo-phytodienoate reductase isoform 3
分子名称: 12-oxophytodienoate-10,11-reductase, FLAVIN MONONUCLEOTIDE
著者Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Smith, D.W, Center for Eukaryotic Structural Genomics (CESG)
登録日2003-08-01
公開日2003-11-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray structure of Arabidopsis At2g06050, 12-oxophytodienoate reductase isoform 3
Proteins, 58, 2005
1HEA
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CARBONIC ANHYDRASE II (CARBONATE DEHYDRATASE) (HCA II) (E.C.4.2.1.1) MUTANT WITH LEU 198 REPLACED BY ARG (L198R)
分子名称: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION
著者Nair, S.K, Christianson, D.W.
登録日1992-07-16
公開日1992-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II.
Biochemistry, 32, 1993
1Q44
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Crystal Structure of an Arabidopsis Thaliana Putative Steroid Sulfotransferase
分子名称: MALONIC ACID, Steroid Sulfotransferase
著者Phillips Jr, G.N, Smith, D.W, Johnson, K.A, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2003-08-01
公開日2003-11-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of At2g03760, a putative steroid sulfotransferase from Arabidopsis thaliana
Proteins, 57, 2004
1HEC
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STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II
分子名称: CARBONIC ANHYDRASE II, ZINC ION
著者Nair, S.K, Christianson, D.W.
登録日1992-07-16
公開日1992-10-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II.
Biochemistry, 32, 1993
1Q7G
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Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline
分子名称: Homoserine dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE-5-HYDROXY-4-OXONORVALINE, SODIUM ION
著者Jacques, S.L, Mirza, I.A, Ejim, L, Koteva, K, Hughes, D.W, Green, K, Kinach, R, Honek, J.F, Lai, H.K, Berghuis, A.M, Wright, G.D.
登録日2003-08-18
公開日2003-10-21
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Enzyme assisted suicide: Molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase
Chem.Biol., 10, 2003
6JPH
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Crystal structure of the catalytic domain of a multi-domain alginate lyase Dp0100 from thermophilic bacterium Defluviitalea phaphyphila
分子名称: ACETATE ION, Alginate lyase, CALCIUM ION, ...
著者Ji, S.Q, Dix, S.R, Aziz, A, Sedelnikova, S.E, Li, F.L, Rice, D.W.
登録日2019-03-27
公開日2019-10-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.759 Å)
主引用文献The molecular basis of endolytic activity of a multidomain alginate lyase fromDefluviitalea phaphyphila, a representative of a new lyase family, PL39.
J.Biol.Chem., 294, 2019
6JPN
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Crystal structure of the catalytic domain of a multi-domain alginate lyase Dp0100 from thermophilic bacterium Defluviitalea phaphyphila
分子名称: Alginate lyase, CALCIUM ION, MAGNESIUM ION, ...
著者Ji, S.Q, Dix, S.R, Aziz, A, Sedelnikova, S.E, Li, F.L, Rice, D.W.
登録日2019-03-27
公開日2019-10-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The molecular basis of endolytic activity of a multidomain alginate lyase fromDefluviitalea phaphyphila, a representative of a new lyase family, PL39.
J.Biol.Chem., 294, 2019
1GZG
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Complex of a Mg2-dependent porphobilinogen synthase from Pseudomonas aeruginosa (mutant D139N) with 5-fluorolevulinic acid
分子名称: 5-FLUOROLEVULINIC ACID, DELTA-AMINOLEVULINIC ACID DEHYDRATASE, MAGNESIUM ION, ...
著者Frere, F, Schubert, W.-D, Stauffer, F, Frankenberg, N, Neier, R, Jahn, D, Heinz, D.W.
登録日2002-05-21
公開日2002-06-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Structure of porphobilinogen synthase from Pseudomonas aeruginosa in complex with 5-fluorolevulinic acid suggests a double Schiff base mechanism.
J. Mol. Biol., 320, 2002
5VI6
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Crystal structure of histone deacetylase 8 in complex with trapoxin A
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, Histone deacetylase 8, ...
著者Porter, N.J, Christianson, D.W.
登録日2017-04-14
公開日2017-09-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.237 Å)
主引用文献Binding of the Microbial Cyclic Tetrapeptide Trapoxin A to the Class I Histone Deacetylase HDAC8.
ACS Chem. Biol., 12, 2017
5VFX
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Structure of an accessory protein of the pCW3 relaxosome in complex with the origin of transfer (oriT) DNA
分子名称: TcpK, oriT
著者Traore, D.A.K, Wisniewski, J.A, Flanigan, S.F, Conroy, P.J, Panjikar, S, Mok, Y.-F, Lao, C, Griffin, M.D.W, Adams, V, Rood, J.I, Whisstock, J.C.
登録日2017-04-10
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Crystal structure of TcpK in complex with oriT DNA of the antibiotic resistance plasmid pCW3.
Nat Commun, 9, 2018
6HS5
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N-terminal domain including the conserved ImpA_N region of the TssA component of the type VI secretion system from Burkholderia cenocepacia
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, TssA
著者Dix, S.R, Owen, H.J, Sun, R, Ahmad, A, Shastri, S, Spiewak, H.L, Mosby, D.J, Harris, M.J, Batters, S.L, Brooker, T.A, Tzokov, S.B, Sedelnikova, S.E, Baker, P.J, Bullough, P.A, Rice, D.W, Thomas, M.S.
登録日2018-09-28
公開日2018-11-21
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into the function of type VI secretion system TssA subunits.
Nat Commun, 9, 2018
1RJ5
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Crystal Structure of the Extracellular Domain of Murine Carbonic Anhydrase XIV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, CHLORIDE ION, ...
著者Whittington, D.A, Grubb, J.H, Waheed, A, Shah, G.N, Sly, W.S, Christianson, D.W.
登録日2003-11-18
公開日2004-03-09
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes.
J.Biol.Chem., 279, 2004
1N8Z
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Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Herceptin Fab (antibody) - heavy chain, Herceptin Fab (antibody) - light chain, ...
著者Cho, H.-S, Mason, K, Ramyar, K.X, Stanley, A.M, Gabelli, S.B, Denney Jr, D.W, Leahy, D.J.
登録日2002-11-21
公開日2003-02-18
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structure of the Extracellular Region of HER2 Alone and in Complex with the Herceptin Fab
Nature, 421, 2003
1RIP
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RIBOSOMAL PROTEIN S17: CHARACTERIZATION OF THE THREE-DIMENSIONAL STRUCTURE BY 1H-AND 15N-NMR
分子名称: RIBOSOMAL PROTEIN S17
著者Golden, B.L, Hoffman, D.W, Ramakrishnan, V, White, S.W.
登録日1993-08-17
公開日1993-10-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Ribosomal protein S17: characterization of the three-dimensional structure by 1H and 15N NMR.
Biochemistry, 32, 1993
6JQK
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Structure of C34M/N36
分子名称: C34M, N36
著者Yu, D.W, Qin, B.
登録日2019-03-31
公開日2020-04-08
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.498 Å)
主引用文献Structure of C34M/N36
To Be Published
1HM7
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N219L PENTALENENE SYNTHASE
分子名称: PENTALENENE SYNTHASE
著者Seemann, M, Paschall, C.M, Christianson, D.W, Cane, D.E.
登録日2000-12-05
公開日2002-08-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis.
J.Am.Chem.Soc., 124, 2002
1HOZ
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CRYSTAL STRUCTURE OF AN INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE FROM TRYPANOSOMA VIVAX
分子名称: CALCIUM ION, GLYCEROL, INOSINE-ADENOSINE-GUANOSINE-PREFERRING NUCLEOSIDE HYDROLASE
著者Versees, W, Decanniere, K, Pelle, R, Depoorter, J, Parkin, D.W, Steyaert, J.
登録日2000-12-12
公開日2001-12-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax.
J.Mol.Biol., 307, 2001
1HQF
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CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH N-HYDROXY-L-ARGININE
分子名称: ARGINASE 1, MANGANESE (II) ION, N-OMEGA-HYDROXY-L-ARGININE
著者Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W.
登録日2000-12-16
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
Biochemistry, 40, 2001
1HM4
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N219L PENTALENENE SYNTHASE
分子名称: PENTALENENE SYNTHASE
著者Seemann, M, Paschall, C.M, Christianson, D.W, Cane, D.E.
登録日2000-12-04
公開日2002-08-30
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Pentalenene synthase. Analysis of active site residues by site-directed mutagenesis.
J.Am.Chem.Soc., 124, 2002
1HQ8
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CRYSTAL STRUCTURE OF THE MURINE NK CELL-ACTIVATING RECEPTOR NKG2D AT 1.95 A
分子名称: NKG2-D
著者Wolan, D.W, Teyton, L, Rudolph, M.G, Villmow, B, Bauer, S, Busch, D.H, Wilson, I.A.
登録日2000-12-14
公開日2001-03-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of the murine NK cell-activating receptor NKG2D at 1.95 A.
Nat.Immunol., 2, 2001
1HQG
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CRYSTAL STRUCTURE OF THE H141C ARGINASE VARIANT COMPLEXED WITH PRODUCTS ORNITHINE AND UREA
分子名称: ARGINASE 1, L-ornithine, MANGANESE (II) ION, ...
著者Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W.
登録日2000-12-16
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
Biochemistry, 40, 2001

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