1GZG

Complex of a Mg2-dependent porphobilinogen synthase from Pseudomonas aeruginosa (mutant D139N) with 5-fluorolevulinic acid

Summary for 1GZG

• Entry DOI: 10.2210/pdb1gzg/pdb
• Related: 1B4K
• Descriptor: DELTA-AMINOLEVULINIC ACID DEHYDRATASE, 5-FLUOROLEVULINIC ACID, MAGNESIUM ION, ... (7 entities in total)
• Functional Keywords: lyase, heme biosynthesis, 5-fluorolevulinic acid
• Biological source: PSEUDOMONAS AERUGINOSA
• Total number of polymer chains: 2
• Total formula weight: 75027.16

Authors

Frere, F.,Schubert, W.-D.,Stauffer, F.,Frankenberg, N.,Neier, R.,Jahn, D.,Heinz, D.W. (deposition date: 2002-05-21, release date: 2002-06-27, Last modification date: 2023-12-13)

• Primary citation: Frere, F.,Schubert, W.D.,Stauffer, F.,Frankenberg, N.,Neier, R.,Jahn, D.,Heinz, D.W.; Structure of porphobilinogen synthase from Pseudomonas aeruginosa in complex with 5-fluorolevulinic acid suggests a double Schiff base mechanism.; J. Mol. Biol., 320:237-247, 2002; PubMed: 12079382; DOI: 10.1016/S0022-2836(02)00472-2

Experimental method

X-RAY DIFFRACTION (1.66 Å)