1HEB

STRUCTURAL CONSEQUENCES OF HYDROPHILIC AMINO-ACID SUBSTITUTIONS IN THE HYDROPHOBIC POCKET OF HUMAN CARBONIC ANHYDRASE II

Summary for 1HEB

DescriptorCARBONIC ANHYDRASE II, ZINC ION, MERCURY (II) ION, ... (4 entities in total)
Functional Keywordslyase(oxo-acid)
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  P00918
Total number of polymer chains1
Total molecular weight29571.02
Authors
Nair, S.K.,Christianson, D.W. (deposition date: 1992-07-16, release date: 1992-10-15, Last modification date: 2017-11-29)
Primary citation
Nair, S.K.,Christianson, D.W.
Structural consequences of hydrophilic amino acid substitutions in the hydrophobic pocket of human carbonic anhydrase II.
Biochemistry, 32:4506-4514, 1993
PubMed: 8485129 (PDB entries with the same primary citation)
DOI: 10.1021/bi00068a005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers11 0.8% 5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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171588
PDB entries from 2020-11-25