1NJS
| human GAR Tfase in complex with hydrolyzed form of 10-trifluoroacetyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid | 分子名称: | N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID, PHOSPHATE ION, Phosphoribosylglycinamide formyltransferase | 著者 | Zhang, Y, Desharnais, J, Marsilje, T.H, Li, C, Hedrick, M.P, Gooljarsingh, L.T, Tavassoli, A, Benkovic, S.J, Olson, A.J, Boger, D.L, Wilson, I.A. | 登録日 | 2003-01-02 | 公開日 | 2003-06-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Rational Design, Synthesis, Evaluation, and Crystal Structure of a Potent Inhibitor of Human GAR Tfase: 10-(Trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic Acid Biochemistry, 42, 2003
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1OJK
| Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7BE197A and E197S glycosynthase mutants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, GLYCEROL, ... | 著者 | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | 登録日 | 2003-07-10 | 公開日 | 2004-01-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants Chem.Biol., 10, 2003
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1OIN
| Family 1 b-glucosidase from Thermotoga maritima | 分子名称: | 2-deoxy-2-fluoro-alpha-D-glucopyranose, BETA-GLUCOSIDASE A | 著者 | Gloster, T, Zechel, D.L, Boraston, A.B, Boraston, C.M, Macdonald, J.M, Tilbrook, D.M, Stick, R.V, Davies, G.J. | 登録日 | 2003-06-19 | 公開日 | 2003-11-25 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Iminosugar Glycosidase Inhibitors: Structural and Thermodynamic Dissection of the Binding of Isofagomine and 1-Deoxynojirimycin to Beta-Glucosidases J.Am.Chem.Soc., 125, 2003
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1OJI
| Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7B E197A and E197S glycosynthase mutants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, GLYCEROL | 著者 | Ducros, V.M.-A, Tarling, C.A, Zechel, D.L, Brzozowski, A.M, Frandsen, T.P, Von Ossowski, I, Schulein, M, Withers, S.G, Davies, G.J. | 登録日 | 2003-07-10 | 公開日 | 2004-01-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Anatomy of Glycosynthesis: Structure and Kinetics of the Humicola Insolens Cel7B E197A and E197S Glycosynthase Mutants Chem.Biol., 10, 2003
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1N0Q
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1N1H
| Initiation complex of polymerase lambda3 from reovirus | 分子名称: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 3'-DEOXY-GUANOSINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*C)-3', ... | 著者 | Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. | 登録日 | 2002-10-17 | 公開日 | 2002-12-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
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1NPR
| CRYSTAL STRUCTURE OF AQUIFEX AEOLICUS NUSG IN C222(1) | 分子名称: | Transcription antitermination protein nusG | 著者 | Knowlton, J.R, Bubunenko, M, Andrykovitch, M, Guo, W, Routzhan, K.M, Waugh, D.S, Court, D.L, Ji, X. | 登録日 | 2003-01-18 | 公開日 | 2003-03-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | A Spring-Loaded State of NusG in Its Functional Cycle Is Suggested by X-ray Crystallography and Supported by
Site-Directed Mutants Biochemistry, 42, 2003
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1Q5B
| lambda-shaped TRANS and CIS interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | He, W, Cowin, P, Stokes, D.L. | 登録日 | 2003-08-06 | 公開日 | 2003-10-07 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (30 Å) | 主引用文献 | Untangling Desmosomal Knots with Electron Tomography Science, 302, 2003
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1NO4
| Crystal Structure of the pre-assembly scaffolding protein gp7 from the double-stranded DNA bacteriophage phi29 | 分子名称: | HEAD MORPHOGENESIS PROTEIN | 著者 | Morais, M.C, Kanamaru, S, Badasso, M.O, Koti, J.S, Owen, B.A.L, McMurray, C.T, Anderson, D.L, Rossmann, M.G. | 登録日 | 2003-01-15 | 公開日 | 2003-07-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Bacteriophage f29 scaffolding protein gp7 before and after prohead assembly Nat.Struct.Biol., 10, 2003
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1OW3
| Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho-GTPase-activating protein 1, ... | 著者 | Graham, D.L, Lowe, P.N, Grime, G.W, Marsh, M, Rittinger, K, Smerdon, S.J, Gamblin, S.J, Eccleston, J.F. | 登録日 | 2003-03-28 | 公開日 | 2003-05-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | MgF(3)(-) as a Transition State Analog of Phosphoryl Transfer Chem.Biol., 9, 2002
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1N35
| lambda3 elongation complex with four phosphodiester bond formed | 分子名称: | 3'-DEOXY-CYTIDINE-5'-TRIPHOSPHATE, 5'-R(*AP*UP*UP*AP*GP*CP*CP*CP*CP*C)-3', 5'-R(P*GP*GP*GP*GP*G)-3', ... | 著者 | Tao, Y, Farsetta, D.L, Nibert, M.L, Harrison, S.C. | 登録日 | 2002-10-25 | 公開日 | 2002-12-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | RNA Synthesis in a Cage--Structural Studies of Reovirus Polymerase [lambda] 3 Cell(Cambridge,Mass.), 111, 2002
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1QPP
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1QPX
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1PA6
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1Q5C
| S-S-lambda-shaped TRANS and CIS interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | He, W, Cowin, P, Stokes, D.L. | 登録日 | 2003-08-06 | 公開日 | 2003-10-07 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (30 Å) | 主引用文献 | Untangling Desmosomal Knots with Electron Tomography Science, 302, 2003
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1PJL
| Crystal structure of human m-NAD-ME in ternary complex with NAD and Lu3+ | 分子名称: | LUTETIUM (III) ION, NAD-dependent malic enzyme, mitochondrial, ... | 著者 | Yang, Z, Batra, R, Floyd, D.L, Hung, H.-C, Chang, G.-G, Tong, L. | 登録日 | 2003-06-03 | 公開日 | 2003-06-17 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Potent and competitive inhibition of malic enzymes by lanthanide ions Biochem.Biophys.Res.Commun., 274, 2000
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1Q1M
| A Highly Efficient Approach to a Selective and Cell Active PTP1B inhibitors | 分子名称: | 5-{2-FLUORO-5-[3-(3-HYDROXY-2-METHOXYCARBONYL-PHENOXY)-PROPENYL]-PHENYL}-ISOXAZOLE-3-CARBOXYLIC ACID, Protein-tyrosine phosphatase, non-receptor type 1 | 著者 | Liu, G, Xin, Z, Pei, Z, Hajduk, P.J, Abad-Zapatero, C, Hutchins, C.W, Zhao, H, Lubben, T.H, Ballaron, S.J, Haasch, D.L, Kaszubska, W, Rondinone, C.M, Trevillyan, J.M, Jirousek, M.R. | 登録日 | 2003-07-22 | 公開日 | 2003-09-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Fragment screening and assembly: a highly efficient approach to a selective and cell active protein tyrosine phosphatase 1B inhibitor. J.Med.Chem., 46, 2003
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1POD
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1QYC
| Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases | 分子名称: | phenylcoumaran benzylic ether reductase PT1 | 著者 | Min, T, Kasahara, H, Bedgar, D.L, Youn, B, Lawrence, P.K, Gang, D.R, Halls, S.C, Park, H, Hilsenbeck, J.L, Davin, L.B, Kang, C. | 登録日 | 2003-09-10 | 公開日 | 2003-11-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases. J.Biol.Chem., 278, 2003
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1QHM
| ESCHERICHIA COLI PYRUVATE FORMATE LYASE LARGE DOMAIN | 分子名称: | PYRUVATE FORMATE-LYASE | 著者 | Leppanen, V.-M, Merckel, M.C, Ollis, D.L, Wong, K.K, Kozarich, J.W, Goldman, A. | 登録日 | 1999-05-19 | 公開日 | 2000-05-24 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase. Structure Fold.Des., 7, 1999
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1Q5A
| S-shaped trans interactions of cadherins model based on fitting C-cadherin (1L3W) to 3D map of desmosomes obtained by electron tomography | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | He, W, Cowin, P, Stokes, D.L. | 登録日 | 2003-08-06 | 公開日 | 2003-10-07 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (30 Å) | 主引用文献 | Untangling Desmosomal Knots with Electron Tomography Science, 302, 2003
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1QBH
| SOLUTION STRUCTURE OF A BACULOVIRAL INHIBITOR OF APOPTOSIS (IAP) REPEAT | 分子名称: | INHIBITOR OF APOPTOSIS PROTEIN (2MIHB/C-IAP-1), ZINC ION | 著者 | Hinds, M.G, Norton, R.S, Vaux, D.L, Day, C.L. | 登録日 | 1999-04-20 | 公開日 | 1999-10-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat. Nat.Struct.Biol., 6, 1999
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1QYD
| Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases, and their relationship to isoflavone reductases | 分子名称: | pinoresinol-lariciresinol reductase | 著者 | Min, T, Kasahara, H, Bedgar, D.L, Youn, B, Lawrence, P.K, Gang, D.R, Halls, S.C, Park, H, Hilsenbeck, J.L, Davin, L.B, Kang, C. | 登録日 | 2003-09-10 | 公開日 | 2003-11-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures of pinoresinol-lariciresinol and phenylcoumaran benzylic ether reductases and their relationship to isoflavone reductases. J.Biol.Chem., 278, 2003
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1DO8
| CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME | 分子名称: | MALIC ENZYME, MANGANESE (II) ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Yang, Z, Floyd, D.L, Loeber, G, Tong, L. | 登録日 | 1999-12-19 | 公開日 | 2000-03-06 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of a closed form of human malic enzyme and implications for catalytic mechanism. Nat.Struct.Biol., 7, 2000
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1DOD
| THE MOBIL FLAVIN OF 4-OH BENZOATE HYDROXYLASE: MOTION OF A PROSTHETIC GROUP REGULATES CATALYSIS | 分子名称: | 2,4-DIHYDROXYBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE | 著者 | Gatti, D.L, Palfey, B.A, Lah, M.S, Entsch, B, Massey, V, Ballou, D.P, Ludwig, M.L. | 登録日 | 1994-09-06 | 公開日 | 1994-11-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The mobile flavin of 4-OH benzoate hydroxylase. Science, 266, 1994
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