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PDB: 996 件

2B1G
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Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase
分子名称: 7-(3,4-DIHYDROXY-5R-HYDROXYMETHYLTETRAHYDROFURAN-2-YL)-2,2-DIOXO-1,2R,3R,7-TETRAHYDRO-2L6-IMIDAZO[4,5-C][1,2,6]THIADIAZIN-4S-ONE, Bifunctional purine biosynthesis protein PURH, PHOSPHATE ION, ...
著者Xu, L, Chong, Y, Hwang, I, D'Onofrio, A, Amore, K, Beardsley, G.P, Li, C, Olson, A.J, Boger, D.L, Wilson, I.A.
登録日2005-09-15
公開日2006-11-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase.
J.Biol.Chem., 282, 2007
1Z64
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NMR Solution Structure of Pleurocidin in DPC Micelles
分子名称: Pleruocidin
著者Syvitski, R.T, Burton, I, Mattatall, N.R, Douglas, S.E, Jakeman, D.L.
登録日2005-03-21
公開日2005-04-12
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Structural characterization of the antimicrobial peptide pleurocidin from winter flounder.
Biochemistry, 44, 2005
1ZI9
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Crystal Structure Analysis of the dienelactone hydrolase (E36D, C123S) mutant- 1.5 A
分子名称: Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION
著者Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L.
登録日2005-04-27
公開日2005-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
1ZJ4
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Crystal Structure Analysis of the dienelactone hydrolase mutant (E36D, C123S) bound with the PMS moiety of the protease inhibitor, Phenylmethylsulfonyl fluoride (PMSF)- 1.7 A
分子名称: Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION
著者Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L.
登録日2005-04-28
公開日2005-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
1ZI8
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Crystal Structure Analysis of the dienelactone hydrolase mutant(E36D, C123S, A134S, S208G, A229V, K234R)- 1.4 A
分子名称: Carboxymethylenebutenolidase, GLYCEROL, SULFATE ION
著者Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L.
登録日2005-04-27
公開日2005-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase.
Acta Crystallogr.,Sect.D, 61, 2005
2LGN
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Lactococcin 972
分子名称: Lactococcin 972
著者Turner, D.L, Lamosa, P, Martinez, B.
登録日2011-07-29
公開日2012-08-01
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure and properties of lactococcin 972 from Lactococcus lactis
To be Published
2L4T
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GIP/Glutaminase L peptide complex
分子名称: Glutaminase L peptide, Tax1-binding protein 3
著者Zoetewey, D.L, Ovee, M, Banerjee, M, Bhaskaran, R, Mohanty, S.
登録日2010-10-13
公開日2011-04-06
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Promiscuous binding at the crossroads of numerous cancer pathways: insight from the binding of glutaminase interacting protein with glutaminase L.
Biochemistry, 50, 2011
2LFV
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Solution Structure of the SPOR domain from E. coli DamX
分子名称: Protein damX
著者Williams, K.B, Arends, S.J.R, Popham, D.L, Fowler, C.A, Weiss, D.S.
登録日2011-07-15
公開日2012-07-18
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Nuclear Magnetic Resonance Solution Structure of the Peptidoglycan-Binding SPOR Domain from Escherichia coli DamX: Insights into Septal Localization.
Biochemistry, 52, 2013
2LNT
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Solution structure of E60A mutant AGR2
分子名称: Anterior gradient protein 2 homolog
著者Patel, P, Clarke, C.J, Barraclough, D.L, Rudland, P.S, Barraclough, R, Lian, L.
登録日2012-01-04
公開日2013-01-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Metastasis-promoting anterior gradient 2 protein has a dimeric thioredoxin fold structure and a role in cell adhesion.
J.Mol.Biol., 425, 2013
2LNS
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Solution structure of AGR2 residues 41-175
分子名称: Anterior gradient protein 2 homolog
著者Patel, P, Clarke, C.J, Barraclough, D.L, Rudland, P.S, Barraclough, R, Lian, L.
登録日2012-01-04
公開日2013-01-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Metastasis-promoting anterior gradient 2 protein has a dimeric thioredoxin fold structure and a role in cell adhesion.
J.Mol.Biol., 425, 2013
2M5S
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High-resolution NMR structure and cryo-EM imaging support multiple functional roles for the accessory I-domain of phage P22 coat protein
分子名称: Coat protein
著者Rizzo, A.A, Suhanovsky, M.M, Baker, M.L, Fraser, L.C.R, Jones, L.M, Rempel, D.L, Gross, M.L, Chiu, W, Alexandrescu, A.T, Teschke, C.M.
登録日2013-03-05
公開日2014-03-05
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Multiple Functional Roles of the Accessory I-Domain of Bacteriophage P22 Coat Protein Revealed by NMR Structure and CryoEM Modeling.
Structure, 22, 2014
2IU3
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Crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase
分子名称: 1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, POTASSIUM ION
著者Xu, L, Chong, Y, Hwang, I, D'Onofrio, A, Amore, K, Beardsley, G.P, Li, C, Olson, A.J, Boger, D.L, Wilson, I.A.
登録日2006-05-27
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase.
J. Biol. Chem., 282, 2007
2IU0
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crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase
分子名称: 1,5-DIHYDROIMIDAZO[4,5-C][1,2,6]THIADIAZIN-4(3H)-ONE 2,2-DIOXIDE, BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH, POTASSIUM ION
著者Xu, L, Chong, Y, Hwang, I, Onofrio, A.D, Amore, K, Beardsley, G.P, Li, C, Olson, A.J, Boger, D.L, Wilson, I.A.
登録日2006-05-26
公開日2007-02-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structure-Based Design, Synthesis, Evaluation, and Crystal Structures of Transition State Analogue Inhibitors of Inosine Monophosphate Cyclohydrolase
J.Biol.Chem., 282, 2007
2JDD
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Glyphosate N-acetyltransferase bound to acetyl COA and 3-phosphoglycerate
分子名称: 3-PHOSPHOGLYCERIC ACID, ACETYL COENZYME *A, GLYPHOSATE N-ACETYLTRANSFERASE, ...
著者Siehl, D.L, Castle, L.A, Gorton, R, Keenan, R.J.
登録日2007-01-06
公開日2007-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The molecular basis of glyphosate resistance by an optimized microbial acetyltransferase.
J. Biol. Chem., 282, 2007
2MGX
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NMR structure of SRA1p C-terminal domain
分子名称: Steroid receptor RNA activator 1
著者Bilinovich, S.M, Davis, C.M, Morris, D.L, Ray, L.A, Prokop, J.W, Buchan, G.J, Leeper, T.C.
登録日2013-11-10
公開日2014-02-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The C-Terminal Domain of SRA1p Has a Fold More Similar to PRP18 than to an RRM and Does Not Directly Bind to the SRA1 RNA STR7 Region.
J.Mol.Biol., 426, 2014
2IYN
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The co-factor-induced pre-active conformation in PhoB
分子名称: MAGNESIUM ION, PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB
著者Sola, M, Drew, D.L, Blanco, A.G, Gomis-Ruth, F.X, Coll, M.
登録日2006-07-19
公開日2006-08-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献The Cofactor-Induced Pre-Active Conformation in Phob.
Acta Crystallogr.,Sect.D, 62, 2006
2K3V
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Solution Structure of a Tetrahaem Cytochrome from Shewanella Frigidimarina
分子名称: HEME C, Tetraheme cytochrome c-type
著者Paixao, V.B, Turner, D.L, Salgueiro, C.A, Brennan, L, Reid, G.A, Chapman, S.K.
登録日2008-05-19
公開日2009-03-31
最終更新日2019-10-02
実験手法SOLUTION NMR
主引用文献The solution structure of a tetraheme cytochrome from Shewanella frigidimarina reveals a novel family structural motif
Biochemistry, 47, 2008
2MZ9
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Solution structure of oxidized triheme cytochrome PpcA from Geobacter sulfurreducens
分子名称: HEME C, PpcA
著者Morgado, L, Bruix, M, Pokkuluri, R, Salgueiro, C.A, Turner, D.L.
登録日2015-02-08
公開日2016-02-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Redox- and pH-linked conformational changes in triheme cytochrome PpcA from Geobacter sulfurreducens.
Biochem. J., 474, 2017
2JDC
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Glyphosate N-acetyltransferase bound to oxidized COA and sulfate
分子名称: GLYPHOSATE N-ACETYLTRANSFERASE, OXIDIZED COENZYME A, SULFATE ION
著者Siehl, D.L, Castle, L.A, Gorton, R, Keenan, R.J.
登録日2007-01-05
公開日2007-02-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The Molecular Basis of Glyphosate Resistance by an Optimized Microbial Acetyltransferase.
J.Biol.Chem., 282, 2007
2JHE
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N-terminal domain of TyrR transcription factor (residues 1 - 190)
分子名称: 2-(2-ETHOXYETHOXY)ETHANOL, SULFATE ION, TETRAETHYLENE GLYCOL, ...
著者Verger, D, Carr, P.D, Kwok, T, Ollis, D.L.
登録日2007-02-21
公開日2008-06-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the N-Terminal Domain of the Tyrr Transcription Factor Responsible for Gene Regulation of Aromatic Amino Acid Biosynthesis and Transport in Escherichia Coli K12
J.Mol.Biol., 367, 2007
2L4K
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Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139
分子名称: Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2
著者Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A.
登録日2010-10-07
公開日2010-11-17
最終更新日2012-10-03
実験手法SOLUTION NMR
主引用文献Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139.
Protein Pept.Lett., 19, 2012
2L4S
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Promiscuous Binding at the Crossroads of Numerous Cancer Pathways: Insight from the Binding of GIP with Glutaminase L
分子名称: Tax1-binding protein 3
著者Zoetewey, D.L, Ovee, M, Banerjee, M, Bhaskaran, R, Mohanty, S.
登録日2010-10-13
公開日2011-04-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Promiscuous binding at the crossroads of numerous cancer pathways: insight from the binding of glutaminase interacting protein with glutaminase L.
Biochemistry, 50, 2011
2LKV
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Staphylococcal Nuclease PHS variant
分子名称: Thermonuclease
著者Matzapetakis, M, Pais, T.M, Lamosa, P, Turner, D.L, Santos, H.
登録日2011-10-21
公開日2012-09-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Mannosylglycerate stabilizes staphylococcal nuclease with restriction of slow beta-sheet motions.
Protein Sci., 21, 2012
2M22
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Solution structure of the helix II template boundary element from Tetrahymena telomerase RNA
分子名称: 5'-R(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*UP*AP*AP*UP*AP*GP*AP*AP*CP*UP*GP*CP*C)-3'
著者Cash, D.D, Richards, R.J, Theimer, C.A, Finger, D.L, Feigon, J.
登録日2012-12-11
公開日2013-03-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the helix II template boundary element from Tetrahymena telomerase RNA
Nucleic Acids Res., 34, 2006
2KAW
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NMR structure of the mDvl1 PDZ domain in complex with its inhibitor
分子名称: Segment polarity protein dishevelled homolog DVL-1, [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid
著者Lee, H.J, Shao, Y, Wang, N.X, Shi, D.L, Zheng, J.J.
登録日2008-11-17
公開日2009-09-15
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Sulindac inhibits canonical Wnt signaling by blocking the PDZ domain of the protein Dishevelled.
Angew.Chem.Int.Ed.Engl., 48, 2009

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