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PDB: 996 件

1SQD
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Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases
分子名称: 4-hydroxyphenylpyruvate dioxygenase, FE (III) ION
著者Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
登録日2004-03-18
公開日2004-08-17
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
1SQI
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Structural basis for inhibitor selectivity revealed by crystal structures of plant and mammalian 4-hydroxyphenylpyruvate dioxygenases
分子名称: (1-TERT-BUTYL-5-HYDROXY-1H-PYRAZOL-4-YL)[6-(METHYLSULFONYL)-4'-METHOXY-2-METHYL-1,1'-BIPHENYL-3-YL]METHANONE, 4-hydroxyphenylpyruvic acid dioxygenase, FE (III) ION
著者Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
登録日2004-03-18
公開日2004-08-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
1SMQ
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Structure of the Ribonucleotide Reductase Rnr2 Homodimer from Saccharomyces cerevisiae
分子名称: Ribonucleoside-diphosphate reductase small chain 1
著者Sommerhalter, M, Voegtli, W.C, Perlstein, D.L, Ge, J, Stubbe, J, Rosenzweig, A.C.
登録日2004-03-09
公開日2004-08-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of the yeast ribonucleotide reductase Rnr2 and Rnr4 homodimers.
Biochemistry, 43, 2004
1SMS
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Structure of the Ribonucleotide Reductase Rnr4 Homodimer from Saccharomyces cerevisiae
分子名称: MERCURY (II) ION, Ribonucleoside-diphosphate reductase small chain 2
著者Sommerhalter, M, Voegtli, W.C, Perlstein, D.L, Ge, J, Stubbe, J, Rosenzweig, A.C.
登録日2004-03-09
公開日2004-08-10
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structures of the yeast ribonucleotide reductase Rnr2 and Rnr4 homodimers.
Biochemistry, 43, 2004
1T4Q
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Interleukin 1 beta F101W
分子名称: Interleukin-1 beta
著者Adamek, D.H, Guerrero, L, Caspar, D.L.
登録日2004-04-30
公開日2004-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
1T99
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r106g kdo8ps without substrates
分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CADMIUM ION, PHOSPHATE ION
著者Gatti, D.L.
登録日2004-05-16
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Effects of the Arg106==>Gly mutation on the catalytic and conformational cycle of Aquifex aeolicus KDO8P synthase.
To be Published
1T8X
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r106g kdo8ps with pep and a5p
分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, ARABINOSE-5-PHOSPHATE, CADMIUM ION, ...
著者Gatti, D.L.
登録日2004-05-13
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Effects of the Arg106==>Gly mutation on the catalytic and conformational cycle of Aquifex aeolicus KDO8P synthase.
To be Published
1TG5
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Crystal structures of plant 4-hydroxyphenylpyruvate dioxygenases complexed with DAS645
分子名称: 4-hydroxyphenylpyruvate dioxygenase, FE (II) ION, [1-TERT-BUTYL-3-(2,4-DICHLOROPHENYL)-5-HYDROXY-1H-PYRAZOL-4-YL][2-CHLORO-4-(METHYLSULFONYL)PHENYL]METHANONE
著者Yang, C, Pflugrath, J.W, Camper, D.L, Foster, M.L, Pernich, D.J, Walsh, T.A.
登録日2004-05-28
公開日2004-08-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for herbicidal inhibitor selectivity revealed by comparison of crystal structures of plant and Mammalian 4-hydroxyphenylpyruvate dioxygenases
Biochemistry, 43, 2004
1VAP
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THE MONOMERIC ASP49 SECRETORY PHOSPHOLIPASE A2 FROM THE VENOM OF AGKISTRIDON PISCIVORUS PISCIVORUS
分子名称: PHOSPHOLIPASE A2
著者Scott, D.L.
登録日1996-11-15
公開日1997-07-07
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural aspects of interfacial adsorption. A crystallographic and site-directed mutagenesis study of the phospholipase A2 from the venom of Agkistrodon piscivorus piscivorus.
J.Biol.Chem., 272, 1997
1TS3
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H135A MUTANT OF TOXIC SHOCK SYNDROME TOXIN-1 FROM S. AUREUS
分子名称: TOXIC SHOCK SYNDROME TOXIN-1
著者Earhart, C.A, Mitchell, D.T, Murray, D.L, Pinheiro, D.M, Matsumura, M, Schlievert, P.M, Ohlendorf, D.H.
登録日1997-10-10
公開日1998-12-16
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of five mutants of toxic shock syndrome toxin-1 with reduced biological activity.
Biochemistry, 37, 1998
8UWC
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Site-one protease without SPRING
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Membrane-bound transcription factor site-1 protease
著者Kober, D.L.
登録日2023-11-06
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.27 Å)
主引用文献SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain
Nat Commun, 2024
8UW8
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Site-one protease and SPRING
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Membrane-bound transcription factor site-1 protease, ...
著者Kober, D.L.
登録日2023-11-06
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献SPRING licenses S1P-mediated cleavage of SREBP2 by displacing an inhibitory pro-domain
Nat Commun, 2024
1BIK
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X-RAY STRUCTURE OF BIKUNIN FROM THE HUMAN INTER-ALPHA-INHIBITOR COMPLEX
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BIKUNIN, SULFATE ION
著者Xu, Y, Carr, P.D, Guss, J.M, Ollis, D.L.
登録日1997-11-26
公開日1999-03-16
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of bikunin from the inter-alpha-inhibitor complex: a serine protease inhibitor with two Kunitz domains.
J.Mol.Biol., 276, 1998
1BHN
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NUCLEOSIDE DIPHOSPHATE KINASE ISOFORM A FROM BOVINE RETINA
分子名称: GUANOSINE-3',5'-MONOPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, NUCLEOSIDE DIPHOSPHATE TRANSFERASE
著者Ladner, J.E, Abdulaev, N.G, Kakuev, D.L, Karaschuk, G.N, Tordova, M, Eisenstein, E, Fujiwara, J.H, Ridge, K.D, Gilliland, G.L.
登録日1998-06-10
公開日1999-02-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The three-dimensional structures of two isoforms of nucleoside diphosphate kinase from bovine retina.
Acta Crystallogr.,Sect.D, 55, 1999
1BE4
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NUCLEOSIDE DIPHOSPHATE KINASE ISOFORM B FROM BOVINE RETINA
分子名称: CYCLIC GUANOSINE MONOPHOSPHATE, NUCLEOSIDE DIPHOSPHATE TRANSFERASE
著者Ladner, J.E, Abdulaev, N.G, Kakuev, D.L, Karaschuk, G.N, Tordova, M, Eisenstein, E, Fujiwara, J.H, Ridge, K.D, Gilliland, G.L.
登録日1998-05-19
公開日1999-01-13
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Nucleoside diphosphate kinase from bovine retina: purification, subcellular localization, molecular cloning, and three-dimensional structure.
Biochemistry, 37, 1998
1C3I
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HUMAN STROMELYSIN-1 CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812
分子名称: 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER, CALCIUM ION, STROMELYSIN-1, ...
著者Steele, D.L, Kammlott, R.U, Crowther, R.L, Birktoft, J.J, Dunten, P, Engler, J.E.
登録日1999-07-27
公開日2000-07-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1.
Protein Eng., 13, 2000
1CC8
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CRYSTAL STRUCTURE OF THE ATX1 METALLOCHAPERONE PROTEIN
分子名称: BENZAMIDINE, MERCURY (II) ION, PROTEIN (METALLOCHAPERONE ATX1)
著者Rosenzweig, A.C, Huffman, D.L, Pufahl, M.Y.R.A, Hou, T.V.O, Wernimont, A.K.
登録日1999-03-04
公開日1999-12-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Crystal structure of the Atx1 metallochaperone protein at 1.02 A resolution.
Structure Fold.Des., 7, 1999
1C8T
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HUMAN STROMELYSIN-1 (E202Q) CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812
分子名称: 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER, CALCIUM ION, STROMELYSIN-1, ...
著者Steele, D.L, el-Kabbani, O, Dunten, P, Crowther, R.L.
登録日1999-07-29
公開日2000-07-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1.
Protein Eng., 13, 2000
1CC7
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CRYSTAL STRUCTURE OF THE ATX1 METALLOCHAPERONE PROTEIN
分子名称: BENZAMIDINE, PROTEIN (METALLOCHAPERONE ATX1)
著者Rosenzweig, A.C, Huffman, D.L, Pufahl, M.Y.R.A, Hou, T.V.O, Wernimont, A.K.
登録日1999-03-04
公開日1999-12-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Crystal structure of the Atx1 metallochaperone protein at 1.02 A resolution.
Structure Fold.Des., 7, 1999
1AMO
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THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES
分子名称: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Wang, M, Roberts, D.L, Paschke, R, Shea, T.M, Masters, B.S.S, Kim, J.J.P.
登録日1997-06-17
公開日1998-06-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes.
Proc.Natl.Acad.Sci.USA, 94, 1997
1CO4
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SOLUTION STRUCTURE OF A ZINC DOMAIN CONSERVED IN YEAST COPPER-REGULATED TRANSCRIPTION FACTORS
分子名称: PROTEIN (ACTIVATOR OF METALLOTHIONEIN 1), ZINC ION
著者Turner, R.B, Smith, D.L, Zawrotny, M.E, Summers, M.F, Posewitz, M.C, Winge, D.R.
登録日1999-06-04
公開日1999-06-10
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of a zinc domain conserved in yeast copper-regulated transcription factors.
Nat.Struct.Biol., 5, 1998
1CWW
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SOLUTION STRUCTURE OF THE CASPASE RECRUITMENT DOMAIN (CARD) FROM APAF-1
分子名称: APOPTOTIC PROTEASE ACTIVATING FACTOR 1
著者Day, C.L, Dupont, C, Lackmann, M, Vaux, D.L, Hinds, M.G.
登録日1999-08-26
公開日2000-01-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1.
Cell Death Differ., 6, 1999
1D9E
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STRUCTURE OF E. COLI KDO8P SYNTHASE
分子名称: 3-DEOXY-D-MANNO-OCTULOSONATE 8-PHOSPHATE SYNTHASE, SULFATE ION
著者Radaev, S, Dastidar, P, Patel, M, Woodard, R.W, Gatti, D.L.
登録日1999-10-27
公開日2000-05-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and mechanism of 3-deoxy-D-manno-octulosonate 8-phosphate synthase.
J.Biol.Chem., 275, 2000
2LNS
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Solution structure of AGR2 residues 41-175
分子名称: Anterior gradient protein 2 homolog
著者Patel, P, Clarke, C.J, Barraclough, D.L, Rudland, P.S, Barraclough, R, Lian, L.
登録日2012-01-04
公開日2013-01-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Metastasis-promoting anterior gradient 2 protein has a dimeric thioredoxin fold structure and a role in cell adhesion.
J.Mol.Biol., 425, 2013
2M5S
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High-resolution NMR structure and cryo-EM imaging support multiple functional roles for the accessory I-domain of phage P22 coat protein
分子名称: Coat protein
著者Rizzo, A.A, Suhanovsky, M.M, Baker, M.L, Fraser, L.C.R, Jones, L.M, Rempel, D.L, Gross, M.L, Chiu, W, Alexandrescu, A.T, Teschke, C.M.
登録日2013-03-05
公開日2014-03-05
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Multiple Functional Roles of the Accessory I-Domain of Bacteriophage P22 Coat Protein Revealed by NMR Structure and CryoEM Modeling.
Structure, 22, 2014

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