1C8T
HUMAN STROMELYSIN-1 (E202Q) CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812
Summary for 1C8T
Entry DOI | 10.2210/pdb1c8t/pdb |
Related | 1C3I 1HFS 1SLM |
Descriptor | STROMELYSIN-1, ZINC ION, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | protein-inhibitor complex, mutant protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space, extracellular matrix (Probable): P08254 |
Total number of polymer chains | 2 |
Total formula weight | 38802.83 |
Authors | Steele, D.L.,el-Kabbani, O.,Dunten, P.,Crowther, R.L. (deposition date: 1999-07-29, release date: 2000-07-19, Last modification date: 2024-03-13) |
Primary citation | Steele, D.L.,El-Kabbani, O.,Dunten, P.,Windsor, L.J.,Kammlott, R.U.,Crowther, R.L.,Michoud, C.,Engler, J.A.,Birktoft, J.J. Expression, characterization and structure determination of an active site mutant (Glu202-Gln) of mini-stromelysin-1. Protein Eng., 13:397-405, 2000 Cited by PubMed: 10877850DOI: 10.1093/protein/13.6.397 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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