1C8T
HUMAN STROMELYSIN-1 (E202Q) CATALYTIC DOMAIN COMPLEXED WITH RO-26-2812
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | STROMELYSIN-1 | polymer | 167 | 18692.8 | 2 | UniProt (P08254) Pfam (PF00413) In PDB | Homo sapiens (human) | |
| 2 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | A, B | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 4 | A, B | 2-(2-{2-[(BIPHENYL-4-YLMETHYL)-AMINO]-3-MERCAPTO-PENTANOYLAMINO}-ACETYLAMINO)-3-METHYL-BUTYRIC ACID METHYL ESTER | non-polymer | 457.6 | 2 | Chemie (TR1) | |||
| 5 | water | water | 18.0 | 71 | Chemie (HOH) |
Sequence modifications
A, B: 86 - 252 (UniProt: P08254)
| PDB | External Database | Details |
|---|---|---|
| Gln 202 | Glu 219 | engineered mutation |
| Pro 252 | Ser 269 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37385.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1417.3 | |
| All* | Total formula weight | 38802.8 |
