Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0031012 | cellular_component | extracellular matrix |
B | 0004222 | molecular_function | metalloendopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0008237 | molecular_function | metallopeptidase activity |
B | 0008270 | molecular_function | zinc ion binding |
B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN B 260 |
Chain | Residue |
B | HIS201 |
B | HIS205 |
B | HIS211 |
B | TR1265 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN B 261 |
Chain | Residue |
B | HIS151 |
B | ASP153 |
B | HIS166 |
B | HIS179 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA B 262 |
Chain | Residue |
B | GLY159 |
B | GLY161 |
B | VAL163 |
B | ASP181 |
B | GLU184 |
B | ASP158 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA B 263 |
Chain | Residue |
B | HOH53 |
B | ASP141 |
B | GLY173 |
B | ASN175 |
B | ASP177 |
site_id | AC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA B 264 |
Chain | Residue |
B | HOH42 |
B | ASP107 |
B | ASP182 |
B | GLU184 |
B | GLN185 |
site_id | AC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 260 |
Chain | Residue |
A | HIS201 |
A | HIS205 |
A | HIS211 |
A | TR1265 |
site_id | AC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 261 |
Chain | Residue |
A | HIS151 |
A | ASP153 |
A | HIS166 |
A | HIS179 |
site_id | AC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 262 |
Chain | Residue |
A | ASP158 |
A | GLY159 |
A | GLY161 |
A | VAL163 |
A | ASP181 |
A | GLU184 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CA A 263 |
Chain | Residue |
A | ASP141 |
A | GLY173 |
A | ASN175 |
A | ASP177 |
site_id | BC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CA A 264 |
Chain | Residue |
A | ASP107 |
A | ASP182 |
A | GLU184 |
site_id | BC2 |
Number of Residues | 20 |
Details | BINDING SITE FOR RESIDUE TR1 A 265 |
Chain | Residue |
A | ASN162 |
A | VAL163 |
A | LEU164 |
A | ALA165 |
A | LEU197 |
A | HIS201 |
A | GLN202 |
A | HIS211 |
A | ALA217 |
A | LEU218 |
A | TYR220 |
A | PRO221 |
A | LEU222 |
A | TYR223 |
A | HIS224 |
A | ZN260 |
B | PRO87 |
B | ALA213 |
B | THR215 |
B | TYR220 |
site_id | BC3 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE TR1 B 265 |
Chain | Residue |
A | HOH41 |
A | PRO87 |
A | THR215 |
A | GLU216 |
B | ASN162 |
B | LEU164 |
B | VAL198 |
B | HIS201 |
B | GLN202 |
B | HIS205 |
B | HIS211 |
B | ALA217 |
B | LEU218 |
B | TYR220 |
B | PRO221 |
B | LEU222 |
B | TYR223 |
B | HIS224 |
B | ZN260 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | GLN202 | |
B | GLN202 | |
site_id | SWS_FT_FI2 |
Number of Residues | 32 |
Details | BINDING: |
Chain | Residue | Details |
A | ASP107 | |
A | GLY173 | |
A | ASN175 | |
A | ASP177 | |
A | HIS179 | |
A | ASP181 | |
A | ASP182 | |
A | GLU184 | |
B | ASP107 | |
B | ASP141 | |
B | HIS151 | |
A | ASP141 | |
B | ASP153 | |
B | ASP158 | |
B | GLY159 | |
B | GLY161 | |
B | VAL163 | |
B | HIS166 | |
B | GLY173 | |
B | ASN175 | |
B | ASP177 | |
B | HIS179 | |
A | HIS151 | |
B | ASP181 | |
B | ASP182 | |
B | GLU184 | |
A | ASP153 | |
A | ASP158 | |
A | GLY159 | |
A | GLY161 | |
A | VAL163 | |
A | HIS166 | |
Chain | Residue | Details |
A | HIS201 | |
A | HIS205 | |
A | HIS211 | |
B | HIS201 | |
B | HIS205 | |
B | HIS211 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hfs |
Chain | Residue | Details |
A | MET219 | |
A | GLN202 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hfs |
Chain | Residue | Details |
B | MET219 | |
B | GLN202 | |
site_id | CSA3 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1hfs |
Chain | Residue | Details |
A | GLN202 | |
site_id | CSA4 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1hfs |
Chain | Residue | Details |
B | GLN202 | |
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 591 |
Chain | Residue | Details |
A | HIS201 | metal ligand |
A | GLN202 | proton acceptor, proton donor |
A | HIS205 | metal ligand |
A | HIS211 | metal ligand |
site_id | MCSA2 |
Number of Residues | 4 |
Details | M-CSA 591 |
Chain | Residue | Details |
B | HIS201 | metal ligand |
B | GLN202 | proton acceptor, proton donor |
B | HIS205 | metal ligand |
B | HIS211 | metal ligand |