1JWJ
 
 | | Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (Delta 65) with W457F Mutation at Tetrahydrobiopterin Binding Site | | Descriptor: | 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... | | Authors: | Aoyagi, M, Arvai, A.S, Ghosh, S, Stuehr, D.J, Tainer, J.A, Getzoff, E.D. | | Deposit date: | 2001-09-04 | | Release date: | 2001-10-31 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457.
Biochemistry, 40, 2001
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1ZBU
 | | crystal structure of full-length 3'-exonuclease | | Descriptor: | 3'-5' exonuclease ERI1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION | | Authors: | Cheng, Y, Patel, D.J. | | Deposit date: | 2005-04-08 | | Release date: | 2006-09-19 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.998 Å) | | Cite: | Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA
To be Published
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1ZL9
 | | Crystal Structure of a major nematode C.elegans specific GST (CE01613) | | Descriptor: | GLUTATHIONE, glutathione S-transferase 5 | | Authors: | Kriksunov, I.A, Liu, Q, Schuller, D.J, Campbell, A.M, Barrett, J, Brophy, P.M, Hao, Q. | | Deposit date: | 2005-05-05 | | Release date: | 2005-05-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Crystal structure of a major nematode C.elegans specific GST (CE01613)
To be Published
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243D
 | | STRUCTURE OF THE DNA OCTANUCLEOTIDE D(ACGTACGT)2 | | Descriptor: | DNA (5'-D(*AP*CP*GP*TP*AP*CP*GP*T)-3') | | Authors: | Wilcock, D.J, Adams, A, Cardin, C.J, Wakelin, L.P.G. | | Deposit date: | 1996-01-10 | | Release date: | 1996-02-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of the DNA octanucleotide d(ACGTACGT)2.
Acta Crystallogr.,Sect.D, 52, 1996
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2AB9
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2A5R
 | | Complex of tetra-(4-n-methylpyridyl) porphin with monomeric parallel-stranded DNA tetraplex, snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, C-MYC promoter, NMR, 6 struct. | | Descriptor: | (1Z,4Z,9Z,15Z)-5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,23-dihydroporphyrin, 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3' | | Authors: | Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J. | | Deposit date: | 2005-06-30 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
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2A5P
 | | Monomeric parallel-stranded DNA tetraplex with snap-back 3+1 3' G-tetrad, single-residue chain reversal loops, GAG triad in the context of GAAG diagonal loop, NMR, 8 struct. | | Descriptor: | 5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*IP*GP*AP*GP*GP*GP*TP*GP*GP*GP*GP*AP*AP*GP*G)-3' | | Authors: | Phan, A.T, Kuryavyi, V.V, Gaw, H.Y, Patel, D.J. | | Deposit date: | 2005-06-30 | | Release date: | 2005-07-26 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter.
Nat.Chem.Biol., 1, 2005
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2CHN
 | | Bacteroides thetaiotaomicron hexosaminidase with O-GlcNAcase activity- NAG-thiazoline complex | | Descriptor: | 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, CALCIUM ION, GLUCOSAMINIDASE, ... | | Authors: | Dennis, R.J, Taylor, E.J, Macauley, M.S, Stubbs, K.A, Turkenburg, J.P, Hart, S.J, Black, G.N, Vocadlo, D.J, Davies, G.J. | | Deposit date: | 2006-03-15 | | Release date: | 2006-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Nat.Struct.Mol.Biol., 13, 2006
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2CHO
 | | Bacteroides thetaiotaomicron hexosaminidase with O-GlcNAcase activity | | Descriptor: | ACETATE ION, CALCIUM ION, GLUCOSAMINIDASE, ... | | Authors: | Dennis, R.J, Taylor, E.J, Macauley, M.S, Stubbs, K.A, Turkenburg, J.P, Hart, S.J, Black, G.N, Vocadlo, D.J, Davies, G.J. | | Deposit date: | 2006-03-16 | | Release date: | 2006-06-19 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structure and Mechanism of a Bacterial B-Glucosaminidase Having O-Glcnacase Activity
Nat.Struct.Mol.Biol., 13, 2006
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2CAZ
 | | ESCRT-I core | | Descriptor: | PROTEIN SRN2, SUPPRESSOR PROTEIN STP22 OF TEMPERATURE-SENSITIVE ALPHA-FACTOR RECEPTOR AND ARGININE PERMEASE, VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS28 | | Authors: | Gill, D.J, Teo, H, Sun, J, Perisic, O, Veprintsev, D.B, Vallis, Y, Emr, S.D, Williams, R.L. | | Deposit date: | 2005-12-23 | | Release date: | 2006-04-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Escrt-I Core and Escrt-II Glue Domain Structures Reveal Role for Glue in Linking to Escrt-I and Membranes.
Cell(Cambridge,Mass.), 125, 2006
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2A64
 | | Crystal Structure of Bacterial Ribonuclease P RNA | | Descriptor: | ribonuclease P RNA | | Authors: | Kazantsev, A.V, Krivenko, A.A, Harrington, D.J, Holbrook, S.R, Adams, P.D, Pace, N.R. | | Deposit date: | 2005-07-01 | | Release date: | 2005-09-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Crystal structure of a bacterial ribonuclease P RNA.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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2B38
 | | Solution structure of kalata B8 | | Descriptor: | kalata B8 | | Authors: | Daly, N.L, Clark, R.J, Plan, M.R, Craik, D.J. | | Deposit date: | 2005-09-19 | | Release date: | 2006-01-31 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif
Biochem.J., 393, 2006
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2BAS
 | | Crystal Structure of the Bacillus subtilis YkuI Protein, with an EAL Domain. | | Descriptor: | BETA-MERCAPTOETHANOL, YkuI protein | | Authors: | Minasov, G, Brunzelle, J.S, Shuvalova, L, Miller, D.J, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2005-10-14 | | Release date: | 2005-11-29 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Crystal structures of YkuI and its complex with second messenger cyclic Di-GMP suggest catalytic mechanism of phosphodiester bond cleavage by EAL domains.
J.Biol.Chem., 284, 2009
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2JZM
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2E4L
 | | Thermodynamic and Structural Analysis of Thermolabile RNase HI from Shewanella oneidensis MR-1 | | Descriptor: | Ribonuclease HI | | Authors: | Tadokoro, T, You, D.J, Chon, H, Matsumura, H, Koga, Y, Takano, K, Kanaya, S. | | Deposit date: | 2006-12-13 | | Release date: | 2007-05-01 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural, thermodynamic, and mutational analyses of a psychrotrophic RNase HI.
Biochemistry, 46, 2007
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2EHG
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8BMQ
 | | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to AMP-PNP | | Descriptor: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT, ... | | Authors: | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-02 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
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8BMS
 | | Cryo-EM structure of the mutant solitary ECF module 2EQ in MSP2N2 lipid nanodiscs in the ATPase closed and ATP-bound conformation | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, ... | | Authors: | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-02 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
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8BMP
 | | Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to ATP and ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Energy-coupling factor transporter ATP-binding protein EcfA1, ... | | Authors: | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-02 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
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8BMR
 | | Cryo-EM structure of the wild-type solitary ECF module in MSP2N2 lipid nanodiscs in the ATPase open and nucleotide-free conformation | | Descriptor: | Energy-coupling factor transporter ATP-binding protein EcfA1, Energy-coupling factor transporter ATP-binding protein EcfA2, Energy-coupling factor transporter transmembrane protein EcfT | | Authors: | Thangaratnarajah, C, Rheinberger, J, Paulino, C, Slotboom, D.J. | | Deposit date: | 2022-11-10 | | Release date: | 2023-08-02 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Expulsion mechanism of the substrate-translocating subunit in ECF transporters.
Nat Commun, 14, 2023
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8BBZ
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8BHU
 | | Crystal Structure of SilF (Ag(I) form | | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SILVER ION, SULFATE ION, ... | | Authors: | Lithgo, R.M, Carr, S.B, Quigley, A.M, Scott, D.J. | | Deposit date: | 2022-11-01 | | Release date: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal Structure of SilF (apo form)
To Be Published
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8C6D
 | | Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate. | | Descriptor: | (2S,3R,4E)-2-aminooctadec-4-ene-1,3-diol, Genome polyprotein, Genome polyprotein (Fragment) | | Authors: | Kingston, N.J, Snowden, J.S, Stonehouse, N.J, Rowlands, D.J, Hogle, J.M. | | Deposit date: | 2023-01-11 | | Release date: | 2023-02-22 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Production of antigenically stable enterovirus A71 virus-like particles in Pichia pastoris as a vaccine candidate.
Biorxiv, 2023
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8C7P
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8CVN
 | | Cryo-EM Structure of Human 15-PGDH in Complex with Small Molecule SW209415 | | Descriptor: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 2-[butyl(oxidanyl)-$l^{3}-sulfanyl]-4-(2,3-dimethylimidazol-4-yl)-6-(1,3-thiazol-2-yl)thieno[2,3-b]pyridin-3-amine | | Authors: | Huang, W, Taylor, D.J. | | Deposit date: | 2022-05-18 | | Release date: | 2023-03-01 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system.
Nat Commun, 14, 2023
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