Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (Delta 65) with W457F Mutation at Tetrahydrobiopterin Binding Site

Summary for 1JWJ

DescriptorNitric Oxide Synthase, octyl beta-D-glucopyranoside, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total)
Functional Keywordsnitric oxide l-arginine monooxygenase, heme, dimer, nos, oxidoreductase
Biological sourceMus musculus (house mouse)
Total number of polymer chains2
Total molecular weight103417.02
Aoyagi, M.,Arvai, A.S.,Ghosh, S.,Stuehr, D.J.,Tainer, J.A.,Getzoff, E.D. (deposition date: 2001-09-04, release date: 2001-10-31, Last modification date: 2020-07-29)
Primary citation
Aoyagi, M.,Arvai, A.S.,Ghosh, S.,Stuehr, D.J.,Tainer, J.A.,Getzoff, E.D.
Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457.
Biochemistry, 40:12826-12832, 2001
PubMed: 11669619 (PDB entries with the same primary citation)
DOI: 10.1021/bi011183k
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers6 0.1% 2.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-08-05