1JWJ
Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (Delta 65) with W457F Mutation at Tetrahydrobiopterin Binding Site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nitric Oxide Synthase | polymer | 433 | 50081.9 | 2 | UniProt (P29477) Pfam (PF02898) | Mus musculus (house mouse) | NOS, type II, Inducible NOS, INOS, Macrophage NOS, MAC-NOS |
| 2 | C, I (A, B) | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 2 | Chemie (BOG) | |||
| 3 | D, J (A, B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | E, K (A, B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 2 | Chemie (H4B) | |||
| 5 | F, G, H, N, O... (A, B) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 6 | L, M (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | T, U (A, B) | water | water | 18.0 | 332 | Chemie (HOH) |
Sequence modifications
A, B: 66 - 498 (UniProt: P29477)
| PDB | External Database | Details |
|---|---|---|
| Phe 457 | Trp 457 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 100163.8 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3253.2 | |
| All* | Total formula weight | 103417.0 |
