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PDB: 2998 件

2GQD
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The crystal structure of B-ketoacyl-ACP synthase II (FabF) from Staphylococcus aureus
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Miller, D.J, White, S.W, Zhang, Y.M, Rock, C.O.
登録日2006-04-20
公開日2006-05-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of B-ketoacyl-ACP synthase II (FabF) from Staphylococcus aureus
To be Published
2VGL
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AP2 CLATHRIN ADAPTOR CORE
分子名称: ADAPTOR PROTEIN COMPLEX AP-2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA-1, ...
著者Owen, D.J, Collins, B.M, McCoy, A.J, Evans, P.R.
登録日2007-11-14
公開日2007-12-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Architecture and Functional Model of the Endocytic Ap2 Complex
Cell(Cambridge,Mass.), 109, 2002
2VGI
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HUMAN ERYTHROCYTE PYRUVATE KINASE: R486W MUTANT
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, 2-PHOSPHOGLYCOLIC ACID, MANGANESE (II) ION, ...
著者Valentini, G, Chiarelli, L, Fortin, R, Dolzan, M, Galizzi, A, Abraham, D.J, Wang, C, Bianchi, P, Zanella, A, Mattevi, A.
登録日2007-11-13
公開日2007-11-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.87 Å)
主引用文献Structure and Function of Human Erythrocyte Pyruvate Kinase. Molecular Basis of Nonspherocytic Hemolytic Anemia.
J.Biol.Chem., 277, 2002
2VCC
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Family 89 Glycoside Hydrolase from Clostridium perfringens
分子名称: ALPHA-N-ACETYLGLUCOSAMINIDASE, CALCIUM ION, GLYCEROL, ...
著者Ficko-Blean, E, Stubbs, K.A, Berg, O, Vocadlo, D.J, Boraston, A.B.
登録日2007-09-19
公開日2008-03-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VC9
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Family 89 Glycoside Hydrolase from Clostridium perfringens in complex with 2-acetamido-1,2-dideoxynojirmycin
分子名称: 2-ACETAMIDO-1,2-DIDEOXYNOJIRMYCIN, ALPHA-N-ACETYLGLUCOSAMINIDASE, CALCIUM ION, ...
著者Ficko-Blean, E, Stubbs, K.A, Berg, O, Vocadlo, D.J, Boraston, A.B.
登録日2007-09-19
公開日2008-03-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2VMK
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Crystal Structure of E. coli RNase E Apoprotein - Catalytic Domain
分子名称: RIBONUCLEASE E, SULFATE ION, ZINC ION
著者Koslover, D.J, Callaghan, A.J, Marcaida, M.J, Martick, M, Scott, W.G, Luisi, B.F.
登録日2008-01-28
公開日2008-07-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Crystal Structure of the Escherichia Coli Rnase E Apoprotein and a Mechanism for RNA Degradation.
Structure, 16, 2008
2VCB
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Family 89 Glycoside Hydrolase from Clostridium perfringens in complex with PUGNAc
分子名称: ALPHA-N-ACETYLGLUCOSAMINIDASE, CALCIUM ION, O-(2-ACETAMIDO-2-DEOXY D-GLUCOPYRANOSYLIDENE) AMINO-N-PHENYLCARBAMATE
著者Ficko-Blean, E, Stubbs, K.A, Berg, O, Vocadlo, D.J, Boraston, A.B.
登録日2007-09-19
公開日2008-03-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Mechanistic Insight Into the Basis of Mucopolysaccharidosis Iiib.
Proc.Natl.Acad.Sci.USA, 105, 2008
2GW9
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High-resolution solution structure of the mouse defensin Cryptdin4
分子名称: Defensin-related cryptdin 4
著者Rosengren, K.J, Craik, D.J, Vogel, H.J, Daly, N.L, Ouellette, A.J.
登録日2006-05-04
公開日2006-07-25
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.
J.Biol.Chem., 281, 2006
2VAI
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Solution structure of a B-DNA hairpin at high pressure
分子名称: 5'-D(*AP*GP*GP*AP*TP*CP*CP*TP*UP*TP *TP*GP*GP*AP*TP*CP*CP*T)-3'
著者Williamson, M.P, Wilton, D.J, Ghosh, M, Chary, K.V.A, Akasaka, K.
登録日2007-08-31
公開日2007-09-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural change in a B-DNA helix with hydrostatic pressure.
Nucleic Acids Res., 36, 2008
2GWP
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High-resolution solution structure of the salt-bridge defficient mouse defensin (E15D)-Cryptdin4
分子名称: Defensin-related cryptdin 4
著者Rosengren, K.J, Craik, D.J, Vogel, H.J, Daly, N.L, Ouellette, A.J.
登録日2006-05-05
公開日2006-07-25
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.
J.Biol.Chem., 281, 2006
2H0Z
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Pre-cleavage state of the Thermoanaerobacter tengcongensis glmS ribozyme bound to glucose-6-phosphate
分子名称: 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, glmS ribozyme RNA, ...
著者Klein, D.J, Ferre-D'Amare, A.R.
登録日2006-05-15
公開日2006-09-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis of glmS ribozyme activation by glucosamine-6-phosphate
Science, 313, 2006
2P0B
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Crystal structure of chemically-reduced E.coli nrfB
分子名称: Cytochrome c-type protein nrfB, HEME C
著者Clarke, T.A, Richardson, D.J, Hemmings, A.M.
登録日2007-02-28
公開日2007-08-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献The crystal structure of the pentahaem c-type cytochrome NrfB and characterization of its solution-state interaction with the pentahaem nitrite reductase NrfA.
Biochem.J., 406, 2007
2P8Y
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Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDP:sordarin cryo-EM reconstruction
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J.
登録日2007-03-23
公開日2007-05-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
2P8X
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Fitted structure of ADPR-eEF2 in the 80S:ADPR-eEF2:GDPNP cryo-EM reconstruction
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Elongation factor 2, Elongation factor Tu-B, ...
著者Taylor, D.J, Nilsson, J, Merrill, A.R, Andersen, G.R, Nissen, P, Frank, J.
登録日2007-03-23
公開日2007-05-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (9.7 Å)
主引用文献Structures of modified eEF2.80S ribosome complexes reveal the role of GTP hydrolysis in translocation.
Embo J., 26, 2007
2VAY
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Calmodulin complexed with CaV1.1 IQ peptide
分子名称: CALCIUM ION, CALMODULIN, CHLORIDE ION, ...
著者Halling, D.B, Black, D.J, Pedersen, S.E, Hamilton, S.L.
登録日2007-09-05
公開日2008-09-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Determinants in Cav1 Channels that Regulate the Ca2+ Sensitivity of Bound Calmodulin.
J.Biol.Chem., 284, 2009
2VE8
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Xray structure of FtsK gamma domain (P. aeruginosa)
分子名称: DNA TRANSLOCASE FTSK
著者Lowe, J, Allen, M.A, Sherratt, D.J.
登録日2007-10-17
公開日2008-09-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Molecular Mechanism of Sequence-Directed DNA Loading and Translocation by Ftsk.
Mol.Cell, 31, 2008
2HBS
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF DEOXYHEMOGLOBIN S
分子名称: HEMOGLOBIN S (DEOXY), ALPHA CHAIN, BETA CHAIN, ...
著者Harrington, D.J, Adachi, K, Royer Junior, W.E.
登録日1997-05-06
公開日1997-07-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The high resolution crystal structure of deoxyhemoglobin S.
J.Mol.Biol., 272, 1997
2HIZ
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Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor
分子名称: BENZYL [(1S)-2-({(1S,2R)-1-BENZYL-2-HYDROXY-3-[(3-METHOXYBENZYL)AMINO]PROPYL}AMINO)-2-OXO-1-{[(1-PROPYLBUTYL)SULFONYL]METHYL}ETHYL]CARBAMATE, Beta-secretase 1, PHOSPHATE ION
著者Benson, T.E, Prince, D.B, Tomasselli, A.G, Emmons, T.L, Paddock, D.J.
登録日2006-06-29
公開日2007-01-23
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Design of potent inhibitors of human beta-secretase. Part 1.
Bioorg.Med.Chem.Lett., 17, 2007
2HMJ
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Crystal Structure of the Naphthalene 1,2-Dioxygenase Phe-352-Val Mutant.
分子名称: 1,2-ETHANEDIOL, FE (III) ION, FE2/S2 (INORGANIC) CLUSTER, ...
著者Ferraro, D.J, Okerlund, A.L, Mowers, J.C, Ramaswamy, S.
登録日2006-07-11
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural basis for regioselectivity and stereoselectivity of product formation by naphthalene 1,2-dioxygenase.
J.Bacteriol., 188, 2006
2VCH
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Characterization and engineering of the bifunctional N- and O- glucosyltransferase involved in xenobiotic metabolism in plants
分子名称: 1,2-ETHANEDIOL, HYDROQUINONE GLUCOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE
著者Brazier-Hicks, M, Offen, W.A, Gershater, M.C, Revett, T.J, Lim, E.K, Bowles, D.J, Davies, G.J, Edwards, R.
登録日2007-09-24
公開日2007-10-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants.
Proc.Natl.Acad.Sci.USA, 104, 2007
2VG8
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Characterization and engineering of the bifunctional N- and O- glucosyltransferase involved in xenobiotic metabolism in plants
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, HYDROQUINONE GLUCOSYLTRANSFERASE, ...
著者Brazier-Hicks, M, Offen, W.A, Gershater, M.C, Revett, T.J, Lim, E.K, Bowles, D.J, Davies, G.J, Edwards, R.
登録日2007-11-09
公開日2007-12-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Characterization and Engineering of the Bifunctional N- and O-Glucosyltransferase Involved in Xenobiotic Metabolism in Plants.
Proc.Natl.Acad.Sci.USA, 104, 2007
2UZS
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A transforming mutation in the pleckstrin homology domain of AKT1 in cancer (AKT1-PH_E17K)
分子名称: INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE, RAC-alpha serine/threonine-protein kinase
著者Carpten, J.D, Faber, A.L, Horn, C, Donoho, G.P, Briggs, S.L, Robbins, C.M, Hostetter, G, Boguslawski, S, Moses, T.Y, Savage, S, Uhlik, M, Lin, A, Du, J, Qian, Y.W, Zeckner, D.J, Tucker-Kellogg, G, Touchman, J, Patel, K, Mousses, S, Bittner, M, Schevitz, R, Lai, M.H, Blanchard, K.L, Thomas, J.E.
登録日2007-05-01
公開日2007-07-17
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
Nature, 448, 2007
2V25
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Structure of the Campylobacter jejuni antigen Peb1A, an aspartate and glutamate receptor with bound aspartate
分子名称: ASPARTIC ACID, MAJOR CELL-BINDING FACTOR, ZINC ION
著者Muller, A, Dodson, E, del Rocio Leon-Kempis, M, Kelly, D.J, Wilkinson, A.J, Wilson, K.S.
登録日2007-06-01
公開日2007-06-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献A Bacterial Virulence Factor with a Dual Role as an Adhesin and a Solute Binding-Protein: The Crystal Structure at 1.5 A Resolution of the Peb1A Protein from the Food-Borne Human Pathogen Campylobacter Jejuni
J.Mol.Biol., 372, 2007
2HT8
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N8 neuraminidase in complex with oseltamivir
分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, Neuraminidase
著者Russell, R.J, Haire, L.F, Stevens, D.J, Collins, P.J, Lin, Y.P, Blackburn, G.M, Hay, A.J, Gamblin, S.J, Skehel, J.J.
登録日2006-07-25
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Nature, 443, 2006
2HMM
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Crystal Structure of Naphthalene 1,2-Dioxygenase Bound to Anthracene
分子名称: 1,2-ETHANEDIOL, ANTHRACENE, FE (III) ION, ...
著者Ferraro, D.J, Okerlund, A.L, Mowers, J.C, Ramaswamy, S.
登録日2006-07-11
公開日2006-10-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural basis for regioselectivity and stereoselectivity of product formation by naphthalene 1,2-dioxygenase.
J.Bacteriol., 188, 2006

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