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PDB: 2999 件

2N2Q
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NMR solution structure of HsAFP1
分子名称: Defensin-like protein 1
著者Harvey, P.J, Craik, D.J, Vriens, K.
登録日2015-05-11
公開日2015-07-22
最終更新日2015-08-19
実験手法SOLUTION NMR
主引用文献Synergistic Activity of the Plant Defensin HsAFP1 and Caspofungin against Candida albicans Biofilms and Planktonic Cultures.
Plos One, 10, 2015
2NA5
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NMR solution structure of vitamin B12 conjugates of PYY3-36
分子名称: CYANOCOBALAMIN, Peptide YY
著者Doyle, R.P, Henry, K.E, Roth, C.L, Kerwood, D.J, Allis, D.G, Holz, G.G, Zubieta, J.
登録日2015-12-21
公開日2016-09-21
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Solution Structure and Constrained Molecular Dynamics Study of Vitamin B12 Conjugates of the Anorectic Peptide PYY(3-36).
Chemmedchem, 11, 2016
2N5H
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PltL-holo
分子名称: 4'-PHOSPHOPANTETHEINE, Peptidyl carrier protein PltL
著者Jaremko, M.J, Lee, D.J, Burkart, M.D.
登録日2015-07-17
公開日2015-09-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL.
J.Am.Chem.Soc., 137, 2015
4QXH
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Crystal structure of histone demethylase KDM2A-H3K36ME1 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-20
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4R32
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Crystal Structure Analysis of Pyk2 and Paxillin LD motifs
分子名称: Paxillin, Protein-tyrosine kinase 2-beta
著者Vanarotti, M, Miller, D.J, Guibao, C.D, Nourse, A, Zheng, J.J.
登録日2014-08-13
公開日2014-09-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.505 Å)
主引用文献Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
4QX7
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Crystal structure of histone demethylase kdm2a-h3k36me2 with alpha-kg
分子名称: 2-OXOGLUTARIC ACID, Histone H3.2, Lysine-specific demethylase 2A, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-18
公開日2014-11-05
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXP
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Crystal structure of hSTING(G230I) in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
2OE6
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2.4A X-ray crystal structure of unliganded RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang
分子名称: RNA (5'-R(*CP*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*C)-3')
著者Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J.
登録日2006-12-28
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Apramycin recognition by the human ribosomal decoding site.
Blood Cells Mol.Dis., 38, 2007
2OGB
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Crystal structure of the C-terminal domain of mouse Nrdp1
分子名称: GLYCEROL, RING finger protein 41, THIOCYANATE ION
著者Bouyain, S, Leahy, D.J.
登録日2007-01-05
公開日2007-01-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3.
Protein Sci., 16, 2007
2O0I
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crystal structure of the R185A mutant of the N-terminal domain of the Group B Streptococcus Alpha C protein
分子名称: C protein alpha-antigen
著者Hogle, J.M, Filman, D.J, Baron, M.J, Madoff, L.C, Iglesias, A.
登録日2006-11-27
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B streptococci into host cells.
J.Biol.Chem., 282, 2007
4ONQ
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Crystal structure of ntDRM E283S/R309S/F310S/Y590S/D591S mutant
分子名称: DNA methyltransferase, SINEFUNGIN
著者Du, J, Patel, D.J.
登録日2014-01-28
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Molecular Mechanism of Action of Plant DRM De Novo DNA Methyltransferases.
Cell(Cambridge,Mass.), 157, 2014
2LJS
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Solution structure of MCoTI-V
分子名称: Trypsin inhibitor 3
著者Daly, N.L, Craik, D.J.
登録日2011-09-23
公開日2012-08-08
最終更新日2019-12-25
実験手法SOLUTION NMR
主引用文献Cyclic Peptides Arising by Evolutionary Parallelism via Asparaginyl-Endopeptidase-Mediated Biosynthesis.
Plant Cell, 24, 2012
4PGF
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The structure of mono-acetylated SAHH
分子名称: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Kavran, J.M, Wang, Y, Cole, P.A, Leahy, D.J.
登録日2014-05-01
公開日2014-10-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Regulation of s-adenosylhomocysteine hydrolase by lysine acetylation.
J.Biol.Chem., 289, 2014
4P7L
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Structure of Escherichia coli PgaB C-terminal domain, P212121 crystal form
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase
著者Little, D.J, Li, G, Ing, C, DiFrancesco, B, Bamford, N.C, Robinson, H, Nitz, M, Pomes, R, Howell, P.L.
登録日2014-03-27
公開日2014-07-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Modification and periplasmic translocation of the biofilm exopolysaccharide poly-beta-1,6-N-acetyl-D-glucosamine.
Proc.Natl.Acad.Sci.USA, 111, 2014
4RG6
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Crystal structure of APC3-APC16 complex
分子名称: Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog
著者Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A.
登録日2014-09-29
公開日2014-12-24
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
4RG9
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Crystal structure of APC3-APC16 complex (Selenomethionine Derivative)
分子名称: Anaphase-promoting complex subunit 16, Cell division cycle protein 27 homolog
著者Yamaguchi, M, Yu, S, Miller, D.J, Schulman, B.A.
登録日2014-09-29
公開日2014-12-24
最終更新日2017-08-02
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Structure of an APC3-APC16 Complex: Insights into Assembly of the Anaphase-Promoting Complex/Cyclosome.
J.Mol.Biol., 427, 2015
2LEW
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Structural Plasticity of Paneth cell alpha-Defensins: Characterization of Salt-Bridge Deficient Analogues of Mouse Cryptdin-4
分子名称: Alpha-defensin 4
著者Rosengren, K, Andersson, H.S, Haugaard-Kedstrom, L.M, Bengtsson, E, Daly, N.L, Craik, D.J.
登録日2011-06-24
公開日2012-05-16
最終更新日2013-06-19
実験手法SOLUTION NMR
主引用文献The alpha-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance.
Amino Acids, 43, 2012
2L7M
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Solution Structure of the Pitx2 Homeodomain R24H mutant
分子名称: Pituitary homeobox 2
著者Doerdelmann, T, Rance, M, Kojetin, D.J, Baird-Titus, J.M.
登録日2010-12-14
公開日2011-12-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structure of the Pitx2 Homeodomain R24H mutant
To be Published
4QPG
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Crystal structure of empty hepatitis A virus
分子名称: CHLORIDE ION, Capsid protein VP0, Capsid protein VP1, ...
著者Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E.
登録日2014-06-23
公開日2014-10-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Hepatitis A virus and the origins of picornaviruses.
Nature, 517, 2015
4QXC
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Crystal structure of histone demethylase KDM2A-H3K36ME2 with NOG
分子名称: Histone H3.2, Lysine-specific demethylase 2A, N-OXALYLGLYCINE, ...
著者Cheng, Z.J, Patel, D.J.
登録日2014-07-19
公開日2014-11-05
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36.
Genes Dev., 28, 2014
4QXO
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Crystal structure of hSTING(group2) in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QU3
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GES-2 ertapenem acyl-enzyme complex
分子名称: (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, 1,2-ETHANEDIOL, Beta-lactamase GES-2, ...
著者Stewart, N.K, Smith, C.A, Frase, H, Black, D.J, Vakulenko, S.B.
登録日2014-07-10
公開日2014-12-31
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.402 Å)
主引用文献Kinetic and Structural Requirements for Carbapenemase Activity in GES-Type beta-Lactamases.
Biochemistry, 54, 2015
4QXQ
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Crystal structure of hSTING(S162A/Q266I) in complex with DMXAA
分子名称: (5,6-dimethyl-9-oxo-9H-xanthen-4-yl)acetic acid, SULFATE ION, Stimulator of interferon genes protein
著者Gao, P, Patel, D.J.
登録日2014-07-21
公開日2014-09-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Cell Rep, 8, 2014
4QPI
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Crystal structure of hepatitis A virus
分子名称: CHLORIDE ION, Capsid protein VP1, Capsid protein VP2, ...
著者Wang, X, Ren, J, Gao, Q, Hu, Z, Sun, Y, Li, X, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E.
登録日2014-06-23
公開日2014-10-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Hepatitis A virus and the origins of picornaviruses.
Nature, 517, 2015
2M0O
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The solution structure of human PHF1 in complex with H3K36me3
分子名称: H3K36me3 peptide, PHD finger protein 1
著者Song, J, Patel, D.J.
登録日2012-10-30
公開日2013-01-16
最終更新日2013-02-27
実験手法SOLUTION NMR
主引用文献An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting.
Mol.Cell, 49, 2013

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