2LEW
Structural Plasticity of Paneth cell alpha-Defensins: Characterization of Salt-Bridge Deficient Analogues of Mouse Cryptdin-4
Summary for 2LEW
Entry DOI | 10.2210/pdb2lew/pdb |
Related | 2GW9 2GWP 2LEY |
NMR Information | BMRB: 17731 |
Descriptor | Alpha-defensin 4 (1 entity in total) |
Functional Keywords | antimicrobial protein |
Biological source | Mus musculus (mouse) |
Cellular location | Secreted: P28311 |
Total number of polymer chains | 1 |
Total formula weight | 3699.55 |
Authors | Rosengren, K.,Andersson, H.S.,Haugaard-Kedstrom, L.M.,Bengtsson, E.,Daly, N.L.,Craik, D.J. (deposition date: 2011-06-24, release date: 2012-05-16, Last modification date: 2013-06-19) |
Primary citation | Andersson, H.S.,Figueredo, S.M.,Haugaard-Kedstrom, L.M.,Bengtsson, E.,Daly, N.L.,Qu, X.,Craik, D.J.,Ouellette, A.J.,Rosengren, K.J. The alpha-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43:1471-1483, 2012 Cited by PubMed: 22286872DOI: 10.1007/s00726-012-1220-3 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report