2KGG
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2K2F
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2JSQ
| Monomeric Human Telomere DNA Tetraplex with 3+1 Strand Fold Topology, Two Edgewise Loops and Double-Chain Reversal Loop, Form 2 15BrG, NMR, 10 Structures | Descriptor: | HUMAN TELOMERE DNA | Authors: | Kuryavyi, V.V, Phan, A.T, Luu, K.N, Patel, D.J. | Deposit date: | 2007-07-11 | Release date: | 2008-07-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structure of two intramolecular G-quadruplexes formed by natural human telomere sequences in K+ solution. Nucleic Acids Res., 35, 2007
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7JS8
| STRUCTURE OF HUMAN HDAC2 IN COMPLEX WITH AN ETHYL KETONE INHIBITOR CONTAINING A SPIRO-BICYCLIC GROUP (COMPOUND 22) | Descriptor: | (1S)-N-{(1S)-7,7-dihydroxy-1-[4-(2-methylquinolin-6-yl)-1H-imidazol-2-yl]nonyl}-6-methyl-6-azaspiro[2.5]octane-1-carboxamide, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Klein, D.J, Yu, W. | Deposit date: | 2020-08-14 | Release date: | 2021-08-11 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.634 Å) | Cite: | Discovery of Ethyl Ketone-Based Highly Selective HDACs 1, 2, 3 Inhibitors for HIV Latency Reactivation with Minimum Cellular Potency Serum Shift and Reduced hERG Activity. J.Med.Chem., 64, 2021
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2JXR
| STRUCTURE OF YEAST PROTEINASE A | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R)-1-(cyclohexylmethyl)-3,3-difluoro-2,2-dihydroxy-4-(methylamino)-4-oxobutyl]-L-norleucinamide, PROTEINASE A, ... | Authors: | Aguilar, C.F, Badasso, M, Dreyer, T, Cronin, N.B, Newman, M.P, Cooper, J.B, Hoover, D.J, Wood, S.P, Johnson, M.S, Blundell, T.L. | Deposit date: | 1997-04-24 | Release date: | 1997-10-29 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The three-dimensional structure at 2.4 A resolution of glycosylated proteinase A from the lysosome-like vacuole of Saccharomyces cerevisiae. J.Mol.Biol., 267, 1997
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1CNL
| ALPHA-CONOTOXIN IMI | Descriptor: | PROTEIN (ALPHA-CONOTOXIN IMI) | Authors: | Gehrmann, J, Daly, N.L, Craik, D.J. | Deposit date: | 1999-05-20 | Release date: | 1999-05-27 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance. J.Med.Chem., 42, 1999
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1CR3
| SOLUTION CONFORMATION OF THE (+)TRANS-ANTI-BENZO[G]CHRYSENE-DA ADDUCT OPPOSITE DT IN A DNA DUPLEX | Descriptor: | BENZO[G]CHRYSENE, DNA (5'-D(*CP*TP*CP*TP*CP*AP*CP*TP*TP*CP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*TP*GP*AP*GP*AP*G)-3') | Authors: | Suri, A.K, Mao, B, Amin, S, Geacintov, N.E, Patel, D.J. | Deposit date: | 1999-08-12 | Release date: | 2000-02-18 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution conformation of the (+)-trans-anti-benzo[g]chrysene-dA adduct opposite dT in a DNA duplex. J.Mol.Biol., 292, 1999
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2JUB
| Solution structure of IPI* | Descriptor: | Internal protein I | Authors: | Rifat, D, Wright, N.T, Varney, K.M, Weber, D.J, Black, L.W. | Deposit date: | 2007-08-17 | Release date: | 2007-12-11 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Restriction endonuclease inhibitor IPI* of bacteriophage T4: a novel structure for a dedicated target. J.Mol.Biol., 375, 2008
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1HP2
| SOLUTION STRUCTURE OF A TOXIN FROM THE SCORPION TITYUS SERRULATUS (TSTX-K ALPHA) DETERMINED BY NMR. | Descriptor: | TITYUSTOXIN K ALPHA | Authors: | Ellis, K.C, Tenenholz, T.C, Gilly, W.F, Blaustein, M.P, Weber, D.J. | Deposit date: | 2000-12-12 | Release date: | 2001-06-13 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Interaction of a toxin from the scorpion Tityus serrulatus with a cloned K+ channel from squid (sqKv1A). Biochemistry, 40, 2001
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7KSR
| PRC2:EZH1_A from a dimeric PRC2 bound to a nucleosome | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | Authors: | Grau, D.J, Armache, K.J. | Deposit date: | 2020-11-24 | Release date: | 2021-02-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12, 2021
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7KSO
| Cryo-EM structure of PRC2:EZH1-AEBP2-JARID2 | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | Authors: | Grau, D.J, Armache, K.J. | Deposit date: | 2020-11-23 | Release date: | 2021-02-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12, 2021
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1FJB
| NMR Study of an 11-Mer DNA Duplex Containing 7,8-Dihydro-8-Oxoadenine (AOXO) Opposite Thymine | Descriptor: | DNA (5'-D(*CP*GP*TP*AP*CP*(A38)P*CP*AP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*TP*GP*TP*GP*TP*AP*CP*G)-3') | Authors: | Chen, H, Johnson, F, Grollman, A.P, Patel, D.J. | Deposit date: | 1995-12-15 | Release date: | 1996-06-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Studies of the Ionizing Radiation Adduct 7,8-Dihydro-8-Oxoadenine (A Oxo) Positioned Opposite Thymine and Guanine in DNA Duplexes MAGN.RESON.CHEM., 34, 1996
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1E42
| Beta2-adaptin appendage domain, from clathrin adaptor AP2 | Descriptor: | AP-2 COMPLEX SUBUNIT BETA, CHLORIDE ION, DITHIANE DIOL, ... | Authors: | Owen, D.J, Evans, P.R, McMahon, H.T. | Deposit date: | 2000-06-27 | Release date: | 2000-08-21 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Structure and Function of the Beta2-Adaptin Appendage Domain Embo J., 19, 2000
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2LJS
| Solution structure of MCoTI-V | Descriptor: | Trypsin inhibitor 3 | Authors: | Daly, N.L, Craik, D.J. | Deposit date: | 2011-09-23 | Release date: | 2012-08-08 | Last modified: | 2019-12-25 | Method: | SOLUTION NMR | Cite: | Cyclic Peptides Arising by Evolutionary Parallelism via Asparaginyl-Endopeptidase-Mediated Biosynthesis. Plant Cell, 24, 2012
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1IFU
| RICIN A-CHAIN (RECOMBINANT) COMPLEX WITH FORMYCIN | Descriptor: | (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, RICIN | Authors: | Weston, S.A, Tucker, A.D, Thatcher, D.R, Derbyshire, D.J, Pauptit, R.A. | Deposit date: | 1996-07-05 | Release date: | 1998-01-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray structure of recombinant ricin A-chain at 1.8 A resolution. J.Mol.Biol., 244, 1994
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2LEW
| Structural Plasticity of Paneth cell alpha-Defensins: Characterization of Salt-Bridge Deficient Analogues of Mouse Cryptdin-4 | Descriptor: | Alpha-defensin 4 | Authors: | Rosengren, K, Andersson, H.S, Haugaard-Kedstrom, L.M, Bengtsson, E, Daly, N.L, Craik, D.J. | Deposit date: | 2011-06-24 | Release date: | 2012-05-16 | Last modified: | 2013-06-19 | Method: | SOLUTION NMR | Cite: | The alpha-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance. Amino Acids, 43, 2012
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1B43
| FEN-1 FROM P. FURIOSUS | Descriptor: | PROTEIN (FEN-1) | Authors: | Hosfield, D.J, Mol, C.D, Shen, B, Tainer, J.A. | Deposit date: | 1999-01-05 | Release date: | 2000-01-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity. Cell(Cambridge,Mass.), 95, 1998
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1AY1
| ANTI TAQ FAB TP7 | Descriptor: | TP7 FAB | Authors: | Murali, R, Helmer-Citterich, M, Sharkey, D.J, Scalice, E.R, Daiss, J.L, Sullivan, M.A, Murthy, H.M.K. | Deposit date: | 1997-11-13 | Release date: | 1998-05-13 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. Protein Eng., 11, 1998
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1B3P
| 5'-D(*GP*GP*AP*GP*GP*AP*T)-3' | Descriptor: | DNA (5'-D(*GP*GP*AP*GP*GP*AP*T)-3') | Authors: | Kettani, A, Bouaziz, S, Skripkin, E, Majumdar, A, Wang, W, Jones, R.A, Patel, D.J. | Deposit date: | 1998-12-14 | Release date: | 1999-08-31 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Interlocked mismatch-aligned arrowhead DNA motifs. Structure Fold.Des., 7, 1999
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2L7M
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1BA6
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1DSV
| STRUCTURE OF THE MMTV NUCLEOCAPSID PROTEIN (C-TERMINAL ZINC FINGER) | Descriptor: | NUCLEIC ACID BINDING PROTEIN P14, ZINC ION | Authors: | Klein, D.J, Johnson, P.E, Zollars, E.S, De Guzman, R.N, Summers, M.F. | Deposit date: | 2000-01-08 | Release date: | 2000-01-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The NMR structure of the nucleocapsid protein from the mouse mammary tumor virus reveals unusual folding of the C-terminal zinc knuckle. Biochemistry, 39, 2000
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7KTP
| PRC2:EZH1_B from a dimeric PRC2 bound to a nucleosome | Descriptor: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH1, Polycomb protein EED, ... | Authors: | Grau, D.J, Armache, K.J. | Deposit date: | 2020-11-24 | Release date: | 2021-02-03 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun, 12, 2021
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2MPM
| Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: the N-terminal Region of CCR3 Bound to CCL11/Eotaxin-1 | Descriptor: | CCR3, Eotaxin | Authors: | Millard, C.J, Ludeman, J.P, Canals, M, Bridgford, J.L, Hinds, M.G, Clayton, D.J, Christopoulos, A, Payne, R.J, Stone, M.J. | Deposit date: | 2014-05-26 | Release date: | 2014-12-10 | Method: | SOLUTION NMR | Cite: | Structural Basis of Receptor Sulfotyrosine Recognition by a CC Chemokine: The N-Terminal Region of CCR3 Bound to CCL11/Eotaxin-1. Structure, 22, 2014
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1DSQ
| STRUCTURE OF THE MMTV NUCLEOCAPSID PROTEIN (ZINC FINGER 1) | Descriptor: | NUCLEIC ACID BINDING PROTEIN P14, ZINC ION | Authors: | Klein, D.J, Johnson, P.E, Zollars, E.S, De Guzman, R.N, Summers, M.F. | Deposit date: | 2000-01-08 | Release date: | 2000-01-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The NMR structure of the nucleocapsid protein from the mouse mammary tumor virus reveals unusual folding of the C-terminal zinc knuckle. Biochemistry, 39, 2000
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