5JG6
 
 | | APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C | | 分子名称: | Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION | | 著者 | Brown, N.G, Zhang, W, Yu, S, Miller, D.J, Sidhu, S.S, Schulman, B.A. | | 登録日 | 2016-04-19 | | 公開日 | 2016-06-15 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.0013 Å) | | 主引用文献 | Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
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3K1V
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3GYT
 | | Nuclear receptor DAF-12 from parasitic nematode Strongyloides stercoralis in complex with its physiological ligand dafachronic acid delta 4 | | 分子名称: | (14beta,17alpha,25R)-3-oxocholest-4-en-26-oic acid, Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily, SRC1 | | 著者 | Zhou, X.E, Wang, Z, Suino-Powell, K, Motola, D.L, Conneely, A, Ogata, C, Sharma, K.K, Auchus, R.J, Kliewer, S.A, Xu, H.E, Mangelsdorf, D.J. | | 登録日 | 2009-04-05 | | 公開日 | 2009-07-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.
Proc.Natl.Acad.Sci.USA, 106, 2009
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6TQF
 | | The structure of ABC transporter Rv1819c in AMP-PNP bound state | | 分子名称: | ABC transporter ATP-binding protein/permease, DODECYL-BETA-D-MALTOSIDE, MAGNESIUM ION, ... | | 著者 | Rempel, S, Gati, C, Slotboom, D.J, Guskov, A. | | 登録日 | 2019-12-16 | | 公開日 | 2020-04-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
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5J7X
 | | Baeyer-Villiger monooxygenase BVMOAFL838 from Aspergillus flavus | | 分子名称: | Dimethylaniline monooxygenase, putative, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Ferroni, F.M, Tolmie, C, Smit, M.S, Opperman, D.J. | | 登録日 | 2016-04-07 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Catalytic Characterization of a Fungal Baeyer-Villiger Monooxygenase.
Plos One, 11, 2016
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3JPZ
 | | Crystal Structure of Lombricine Kinase | | 分子名称: | Lombricine kinase, NITRATE ION | | 著者 | Bush, D.J, Kirillova, O, Clark, S.A, Fabiola, F, Somasundaram, T, Chapman, M.S. | | 登録日 | 2009-09-04 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The structure of lombricine kinase: implications for phosphagen kinase conformational changes.
J.Biol.Chem., 286, 2011
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6VN5
 | | USP7 IN COMPLEX WITH LIGAND COMPOUND 7 | | 分子名称: | Ubiquitin carboxyl-terminal hydrolase 7, [(2R)-7-(2-aminopyridin-4-yl)-5-chloro-2,3-dihydro-1-benzofuran-2-yl](piperazin-1-yl)methanone | | 著者 | Leger, P.R, Wustrow, D.J, Hu, D.X, Krapp, S, Maskos, K, Blaesse, M. | | 登録日 | 2020-01-29 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
J.Med.Chem., 63, 2020
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3ZLH
 | | Structure of group A Streptococcal enolase | | 分子名称: | ENOLASE | | 著者 | Cork, A.J, Ericsson, D.J, Law, R.H.P, Casey, L.W, Valkov, E, Bertozzi, C, Stamp, A, Aquilina, J.A, Whisstock, J.C, Walker, M.J, Kobe, B. | | 登録日 | 2013-01-31 | | 公開日 | 2014-02-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Stability of the Octameric Structure Affects Plasminogen-Binding Capacity of Streptococcal Enolase.
Plos One, 10, 2015
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3ZYK
 | | Structure of CALM (PICALM) ANTH domain | | 分子名称: | PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN | | 著者 | Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J. | | 登録日 | 2011-08-23 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
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3JBD
 | | Complex of poliovirus with VHH PVSP6A | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Strauss, M, Schotte, L, Thys, B, Filman, D.J, Hogle, J.M. | | 登録日 | 2015-08-26 | | 公開日 | 2016-01-27 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site.
J.Virol., 90, 2016
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6RVX
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3ZYM
 | | Structure of CALM (PICALM) in complex with VAMP8 | | 分子名称: | GLYCEROL, PHOSPHATE ION, PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN, ... | | 著者 | Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J. | | 登録日 | 2011-08-23 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
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6VZO
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6VZM
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6VZN
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6VZL
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6THD
 | | Multiple Genomic RNA-Coat Protein Contacts Play Vital Roles in the Assembly of Infectious Enterovirus-E | | 分子名称: | Genome polyprotein, MYRISTIC ACID, SULFATE ION | | 著者 | Chandler-Bostock, R, Mata, C.P, Bingham, R, Dykeman, E.J, Meng, B, Tuthill, T.J, Rowlands, D.J, Ranson, N.A, Twarock, R, Stockley, P.G. | | 登録日 | 2019-11-19 | | 公開日 | 2020-12-09 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.23 Å) | | 主引用文献 | Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts.
Plos Pathog., 16, 2020
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5JZL
 | | The Structure of Monomeric Ultra Stable Green Fluorescent Protein | | 分子名称: | CHLORIDE ION, Green fluorescent protein, SODIUM ION | | 著者 | Gunn, N.J, Yong, K.J, Scott, D.J, Griffin, M.D.W. | | 登録日 | 2016-05-17 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A Novel Ultra-Stable, Monomeric Green Fluorescent Protein For Direct Volumetric Imaging of Whole Organs Using CLARITY.
Sci Rep, 8, 2018
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5LY6
 | | CryoEM structure of the membrane pore complex of Pneumolysin at 4.5A | | 分子名称: | Pneumolysin | | 著者 | van Pee, K, Neuhaus, A, D'Imprima, E, Mills, D.J, Kuehlbrandt, W, Yildiz, O. | | 登録日 | 2016-09-24 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | CryoEM structures of membrane pore and prepore complex reveal cytolytic mechanism of Pneumolysin.
Elife, 6, 2017
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3JQ3
 | | Crystal Structure of Lombricine Kinase, complexed with substrate ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lombricine kinase | | 著者 | Bush, D.J, Kirillova, O, Clark, S.A, Fabiola, F, Somasundaram, T, Chapman, M.S. | | 登録日 | 2009-09-05 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | | 主引用文献 | The structure of lombricine kinase: implications for phosphagen kinase conformational changes.
J.Biol.Chem., 286, 2011
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4AZ5
 | | Differential inhibition of the tandem GH20 catalytic modules in the pneumococcal exo-beta-D-N-acetylglucosaminidase, StrH | | 分子名称: | (2S,3aR,5R,6S,7R,7aR)-5-(hydroxymethyl)-2-methyl-2,3a,5,6,7,7a-hexahydro-1H-pyrano[3,2-d][1,3]thiazole-6,7-diol, 1,2-ETHANEDIOL, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... | | 著者 | Pluvinage, B, Stubbs, K.A, Vocadlo, D.J, Boraston, A.B. | | 登録日 | 2012-06-22 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Inhibition of the Family 20 Glycoside Hydrolase Catalytic Modules in the Streptococcus Pneumoniae Exo-Beta-D-N-Acetylglucosaminidase, Strh.
Org.Biomol.Chem., 11, 2013
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6VN4
 | | USP7 IN COMPLEX WITH LIGAND COMPOUND 1 | | 分子名称: | 3-({4-hydroxy-1-[(2R)-2-methyl-3-phenylpropanoyl]piperidin-4-yl}methyl)quinazolin-4(3H)-one, Ubiquitin carboxyl-terminal hydrolase 7 | | 著者 | Leger, P.R, Wustrow, D.J, Hu, D.X, Krapp, S, Maskos, K, Blaesse, M. | | 登録日 | 2020-01-29 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.
J.Med.Chem., 63, 2020
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3J0K
 | | Orientation of RNA polymerase II within the human VP16-Mediator-pol II-TFIIF assembly | | 分子名称: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | | 著者 | Bernecky, C, Grob, P, Ebmeier, C.C, Nogales, E, Taatjes, D.J. | | 登録日 | 2011-10-04 | | 公開日 | 2011-10-19 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (36 Å) | | 主引用文献 | Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly.
Plos Biol., 9, 2011
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5LJO
 | | E. coli BAM complex (BamABCDE) by cryoEM | | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | 著者 | Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Schffrin, B, Calabrese, A.N, Ashcroft, A.E, Brockwell, D.J. | | 登録日 | 2016-07-19 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Lateral opening in the intact beta-barrel assembly machinery captured by cryo-EM.
Nat Commun, 7, 2016
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3JBE
 | | Complex of poliovirus with VHH PVSS8A | | 分子名称: | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... | | 著者 | Strauss, M, Schotte, L, Thys, B, Filman, D.J, Hogle, J.M. | | 登録日 | 2015-08-26 | | 公開日 | 2016-01-27 | | 最終更新日 | 2022-12-21 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site.
J.Virol., 90, 2016
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