2X9H
 
 | | CRYSTAL STRUCTURE OF MYOSIN-2 MOTOR DOMAIN IN COMPLEX WITH ADP- METAVANADATE AND PENTACHLOROCARBAZOLE | | 分子名称: | 2,3,4,6,8-PENTACHLORO-9H-CARBAZOL-1-OL, ADP METAVANADATE, MAGNESIUM ION, ... | | 著者 | Selvadurai, J, Kirst, J, Knoelker, H.J, Manstein, D.J. | | 登録日 | 2010-03-19 | | 公開日 | 2011-05-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal Structure of Myosin-2 Motor Domain in Complex with Adp-Metavanadate and Pentachlorocarbazole
To be Published
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5NUX
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5M7S
 | | Structure of human O-GlcNAc hydrolase with bound transition state analog ThiametG | | 分子名称: | (3AR,5R,6S,7R,7AR)-2-(ETHYLAMINO)-5-(HYDROXYMETHYL)-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D][1,3]THIAZOLE-6,7-DIOL, Protein O-GlcNAcase | | 著者 | Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J. | | 登録日 | 2016-10-28 | | 公開日 | 2017-03-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and functional insight into human O-GlcNAcase.
Nat. Chem. Biol., 13, 2017
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5MBU
 | | CeuE (H227A, Y288F variant) a periplasmic protein from Campylobacter jejuni | | 分子名称: | Enterochelin uptake periplasmic binding protein | | 著者 | Wilde, E.J, Blagova, E.V, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. | | 登録日 | 2016-11-08 | | 公開日 | 2017-04-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length.
Sci Rep, 7, 2017
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5I4E
 | | Crystal Structure of Human Nonmuscle Myosin 2C motor domain | | 分子名称: | ADP ORTHOVANADATE, MAGNESIUM ION, Myosin-14,Alpha-actinin A | | 著者 | Chinthalapudi, K, Heissler, S.M, Preller, M, Sellers, J.R, Manstein, D.J. | | 登録日 | 2016-02-11 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Mechanistic insights into the active site and allosteric communication pathways in human nonmuscle myosin-2C.
Elife, 6, 2017
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5I35
 | | Structure of the Human mitochondrial kinase COQ8A R611K with AMPPNP (Cerebellar Ataxia and Ubiquinone Deficiency Through Loss of Unorthodox Kinase Activity) | | 分子名称: | Atypical kinase ADCK3, mitochondrial, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Bingman, C.A, Stefely, J.A, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) | | 登録日 | 2016-02-09 | | 公開日 | 2016-08-17 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.
Mol.Cell, 63, 2016
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5O8O
 | | N. crassa Tom40 model based on cryo-EM structure of the TOM core complex at 6.8 A | | 分子名称: | Mitochondrial import receptor subunit tom40 | | 著者 | Bausewein, T, Mills, D.J, Nussberger, S, Nitschke, B, Kuehlbrandt, W. | | 登録日 | 2017-06-13 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | | 主引用文献 | Cryo-EM Structure of the TOM Core Complex from Neurospora crassa.
Cell, 170, 2017
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5I2A
 | | 1,2-propanediol Dehydration in Roseburia inulinivorans; Structural Basis for Substrate and Enantiomer Selectivity | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Diol-dehydratase | | 著者 | LaMattina, J.W, Reitzer, P, Kapoor, S, Galzerani, F, Koch, D.J, Gouvea, I.E, Lanzilotta, W.N. | | 登録日 | 2016-02-08 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | 1,2-Propanediol Dehydration in Roseburia inulinivorans: STRUCTURAL BASIS FOR SUBSTRATE AND ENANTIOMER SELECTIVITY.
J.Biol.Chem., 291, 2016
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1QOM
 | | MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DIMER (DELTA 65) WITH SWAPPED N-TERMINAL HOOK | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, NITRIC OXIDE SYNTHASE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Crane, B.R, Rosenfeld, R.A, Arvai, A.S, Tainer, J.A, Stuehr, D.J, Getzoff, E.D. | | 登録日 | 1999-11-15 | | 公開日 | 1999-12-15 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | N-Terminal Domain Swapping and Metal Ion Binding in Nitric Oxide Synthase Dimerization
Embo J., 18, 1999
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7UO0
 | | E.coli RNaseP Holoenzyme with Mg2+ | | 分子名称: | CALCIUM ION, Precursor tRNA substrate G(-1) G(-2), RNase P RNA, ... | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
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7UO1
 | | E.coli RNaseP Holoenzyme with Mg2+ | | 分子名称: | CALCIUM ION, E.coli RNase P RNA, Precursor tRNA substrate U(-1) and A(-2), ... | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
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7UO2
 | | E.coli RNaseP Holoenzyme with Mg2+ | | 分子名称: | MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
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7UO5
 | | E.coli RNaseP Holoenzyme with Mg2+ | | 分子名称: | CALCIUM ION, RNase P RNA, Ribonuclease P protein component | | 著者 | Huang, W, Taylor, D.J. | | 登録日 | 2022-04-12 | | 公開日 | 2022-09-28 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
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4J52
 | | Crystal structure of PLK1 in complex with a pyrimidodiazepinone inhibitor | | 分子名称: | 4-{[(7R)-9-cyclopentyl-7-ethenyl-7-fluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl]amino}-3-methoxy-N-(4-methylpiperazin-1-yl)benzamide, ACETATE ION, Serine/threonine-protein kinase PLK1, ... | | 著者 | Hosfield, D.J, Skene, R.J. | | 登録日 | 2013-02-07 | | 公開日 | 2013-05-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1).
Bioorg.Med.Chem.Lett., 23, 2013
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5I68
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5OCS
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5HHC
 | | Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21/n | | 分子名称: | D- Vascular endothelial growth factor-A, GLYCEROL, Vascular endothelial growth factor A | | 著者 | Uppalapati, M, Lee, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. | | 登録日 | 2016-01-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.
Acs Chem.Biol., 11, 2016
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5FLL
 | | Crystal structure of the 6-carboxyhexanoate-CoA ligase (BioW) from Bacillus subtilis in complex with a Pimeloyl-adenylate | | 分子名称: | 6-CARBOXYHEXANOATE-COA LIGASE, MAGNESIUM ION, PIMELOYL-AMP, ... | | 著者 | Moynie, L, Wang, M, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2015-10-26 | | 公開日 | 2016-11-16 | | 最終更新日 | 2018-06-13 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.
Nat. Chem. Biol., 13, 2017
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7UDP
 | | Crystal structure of COQ8A-CA157 inhibitor complex in space group C2 | | 分子名称: | 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial | | 著者 | Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. | | 登録日 | 2022-03-20 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Small-molecule inhibition of the archetypal UbiB protein COQ8.
Nat.Chem.Biol., 19, 2023
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7U7H
 | | Cysteate acyl-ACP transferase from Alistipes finegoldii | | 分子名称: | 7-keto-8-aminopelargonate synthetase-like enzyme, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Radka, C.D, Miller, D.J, Frank, M.W, Rock, C.O. | | 登録日 | 2022-03-07 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii.
J.Biol.Chem., 298, 2022
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7UDQ
 | | Crystal structure of COQ8A-CA157 inhibitor complex in space group P1 | | 分子名称: | 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial, ... | | 著者 | Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. | | 登録日 | 2022-03-20 | | 公開日 | 2023-01-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Small-molecule inhibition of the archetypal UbiB protein COQ8.
Nat.Chem.Biol., 19, 2023
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5FQH
 | | The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens | | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, BETA-N-ACETYLGALACTOSAMINIDASE, PHOSPHATE ION | | 著者 | Noach, I, Pluvinage, B, Laurie, C, Abe, K.T, Alteen, M, Vocadlo, D.J, Boraston, A.B. | | 登録日 | 2015-12-10 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium Perfringens
J.Mol.Biol., 428, 2016
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5FQE
 | | The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, BETA-N-ACETYLGALACTOSAMINIDASE, BROMIDE ION, ... | | 著者 | Noach, I, Pluvinage, B, Laurie, C, Abe, K.T, Alteen, M, Vocadlo, D.J, Boraston, A.B. | | 登録日 | 2015-12-10 | | 公開日 | 2016-03-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium Perfringens
J.Mol.Biol., 428, 2016
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5I2G
 | | 1,2-propanediol Dehydration in Roseburia inulinivorans; Structural Basis for Substrate and Enantiomer Selectivity | | 分子名称: | Diol dehydratase, S-1,2-PROPANEDIOL | | 著者 | LaMattina, J.W, Reitzer, P, Kapoor, S, Galzerani, F, Koch, D.J, Gouvea, I.E, Lanzilotta, W.N. | | 登録日 | 2016-02-08 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.352 Å) | | 主引用文献 | 1,2-Propanediol Dehydration in Roseburia inulinivorans: STRUCTURAL BASIS FOR SUBSTRATE AND ENANTIOMER SELECTIVITY.
J.Biol.Chem., 291, 2016
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5I3T
 | | Native Structure of the Linalool Dehydratase-Isomerase from Castellaniella defragrans | | 分子名称: | 1,3-BUTANEDIOL, CHLORIDE ION, Linalool dehydratase/isomerase, ... | | 著者 | LaMattina, J.W, Carlock, M, Koch, D.J, Lanzilotta, W.N. | | 登録日 | 2016-02-11 | | 公開日 | 2016-06-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Native Structure of the Linalool Dehydratase-Isomerase from Castellaniella defragrans
To Be Published
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