8HKE
 
 | | dsRNA transporter | | 分子名称: | RNA (37-MER), Systemic RNA interference defective protein 1, ZINC ION | | 著者 | Jiang, D.H, Zhang, J.T. | | 登録日 | 2022-11-25 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-07-31 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Structural insights into double-stranded RNA recognition and transport by SID-1.
Nat.Struct.Mol.Biol., 31, 2024
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8EWF
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3DYO
 | | E. coli (lacZ) beta-galactosidase (H418N) in complex with IPTG | | 分子名称: | 1-methylethyl 1-thio-beta-D-galactopyranoside, Beta-galactosidase, DIMETHYL SULFOXIDE, ... | | 著者 | Juers, D.H, Huber, R.E, Matthews, B.W. | | 登録日 | 2008-07-28 | | 公開日 | 2008-10-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli).
Protein Sci., 18, 2009
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6K1G
 | | Crystal structure of the L-fucose isomerase soaked with Mn2+ from Raoultella sp. | | 分子名称: | L-fucose isomerase, MANGANESE (II) ION | | 著者 | Kim, I.J, Kim, D.H, Nam, K.H, Kim, K.H. | | 登録日 | 2019-05-10 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | Enzymatic synthesis of l-fucose from l-fuculose using a fucose isomerase fromRaoultellasp. and the biochemical and structural analyses of the enzyme.
Biotechnol Biofuels, 12, 2019
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1AZ1
 | | ALRESTATIN BOUND TO C298A/W219Y MUTANT HUMAN ALDOSE REDUCTASE | | 分子名称: | ALDOSE REDUCTASE, ALRESTATIN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H.T, Bohren, K.M, Petsko, G.A, Ringe, D, Gabbay, K.H. | | 登録日 | 1997-11-24 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant.
Biochemistry, 36, 1997
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8FXQ
 | | The Crystal Sturucture of Rhizopuspepsin with a bound modified peptide inhibitor generated by de novo drug design. | | 分子名称: | ALA-CYS-VAL-LYS, CYCLOHEXANE, Rhizopuspepsin, ... | | 著者 | Satyshur, K.A, Rich, D.H, Ripka, A.S. | | 登録日 | 2023-01-25 | | 公開日 | 2023-02-08 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | Aspartic protease inhibitors designed from computer-generated templates bind as predicted.
Org Lett, 3, 2001
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6K1F
 | | Crystal structure of the L-fucose isomerase from Raoultella sp. | | 分子名称: | L-fucose isomerase, MANGANESE (II) ION | | 著者 | Kim, I.J, Kim, D.H, Nam, K.H, Kim, K.H. | | 登録日 | 2019-05-10 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Enzymatic synthesis of l-fucose from l-fuculose using a fucose isomerase fromRaoultellasp. and the biochemical and structural analyses of the enzyme.
Biotechnol Biofuels, 12, 2019
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8XOA
 | | VMAT2 complex with MPP+ | | 分子名称: | 1-methyl-4-phenylpyridin-1-ium, Synaptic vesicular amine transporter,Synaptic vesicular amine transporter,transporterA | | 著者 | Jiang, D.H, Wu, D. | | 登録日 | 2023-12-31 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | | 主引用文献 | VMAT2 complex with MPP+
To Be Published
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8XO9
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8XOB
 | | VMAT2 protonated state | | 分子名称: | Synaptic vesicular amine transporter,transporter B | | 著者 | Jiang, D.H, Wu, D. | | 登録日 | 2023-12-31 | | 公開日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | VMAT2 protonated state
To Be Published
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3DMM
 | | Crystal structure of the CD8 alpha beta/H-2Dd complex | | 分子名称: | Beta-2 microglobulin, H-2 class I histocompatibility antigen, D-D alpha chain, ... | | 著者 | Wang, R, Natarajan, K, Margulies, D.H. | | 登録日 | 2008-07-01 | | 公開日 | 2009-07-14 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position.
J.Immunol., 183, 2009
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1B93
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8IOD
 | | Cryo-EM structure of the PG-901-bound human melanocortin receptor 5 (MC5R)-Gs complex | | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, ... | | 著者 | Feng, W.B, Zhou, Q.T, Chen, X.Y, Dai, A.T, Cai, X.Q, Liu, X, Zhao, F.H, Chen, Y, Ye, C.Y, Xu, Y.N, Cong, Z.T, Li, H, Lin, S, Yang, D.H, Wang, M.W. | | 登録日 | 2023-03-10 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.59 Å) | | 主引用文献 | Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.
Cell Discov, 9, 2023
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8INR
 | | Cryo-EM structure of the alpha-MSH-bound human melanocortin receptor 5 (MC5R)-Gs complex | | 分子名称: | CALCIUM ION, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,HiBiT, ... | | 著者 | Feng, W.B, Zhou, Q.T, Chen, X.Y, Dai, A.T, Cai, X.Q, Liu, X, Zhao, F.H, Chen, Y, Ye, C.Y, Xu, Y.N, Cong, Z.T, Li, H, Lin, S, Yang, D.H, Wang, M.W. | | 登録日 | 2023-03-10 | | 公開日 | 2023-09-20 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Structural insights into ligand recognition and subtype selectivity of the human melanocortin-3 and melanocortin-5 receptors.
Cell Discov, 9, 2023
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3DSL
 | | The Three-dimensional Structure of Bothropasin, the Main Hemorrhagic Factor from Bothrops jararaca venom. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FUROYL-LEUCINE, ... | | 著者 | Muniz, J.R.C, Ambrosio, A, Selistre-de-Araujo, H.S, Oliva, G, Garratt, R.C, Souza, D.H.F. | | 登録日 | 2008-07-13 | | 公開日 | 2008-10-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The three-dimensional structure of bothropasin, the main hemorrhagic factor from Bothrops jararaca venom: Insights for a new classification of snake venom metalloprotease subgroups.
Toxicon, 52, 2008
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3DX5
 | | Crystal structure of the probable 3-DHS dehydratase AsbF involved in the petrobactin synthesis from Bacillus anthracis | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,4-DIHYDROXYBENZOIC ACID, CHLORIDE ION, ... | | 著者 | Kim, Y, Maltseva, N, Stols, L, Eschenfeldt, W, Pfleger, B.F, Sherman, D.H, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2008-07-23 | | 公開日 | 2008-09-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis.
Proc.Natl.Acad.Sci.USA, 105, 2008
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8X5F
 | | human XPR1 in complex with InsP6 | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Jiang, D.H, Yan, R. | | 登録日 | 2023-11-17 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | Human XPR1 structures reveal phosphate export mechanism.
Nature, 2024
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8X5B
 | | Cryo-EM structures of human XPR1 in closed states | | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL, PHOSPHATE ION, ... | | 著者 | Jiang, D.H, Yan, R. | | 登録日 | 2023-11-16 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Human XPR1 structures reveal phosphate export mechanism.
Nature, 2024
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3DYP
 | | E. coli (lacZ) beta-galactosidase (H418N) | | 分子名称: | Beta-galactosidase, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | | 著者 | Juers, D.H, Huber, R.E, Matthews, B.W. | | 登録日 | 2008-07-28 | | 公開日 | 2008-10-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Direct and indirect roles of His-418 in metal binding and in the activity of beta-galactosidase (E. coli).
Protein Sci., 18, 2009
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8X5E
 | | Cryo-EM structure of human XPR1 in open state | | 分子名称: | PHOSPHATE ION, Solute carrier family 53 member 1, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | | 著者 | Jiang, D.H, Yan, R. | | 登録日 | 2023-11-17 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | | 主引用文献 | Human XPR1 structures reveal phosphate export mechanism.
Nature, 2024
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1AZ2
 | | CITRATE BOUND, C298A/W219Y MUTANT HUMAN ALDOSE REDUCTASE | | 分子名称: | ALDOSE REDUCTASE, CITRIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H, Bohren, K.M, Ringe, D, Petsko, G.A, Gabbay, K.H. | | 登録日 | 1997-11-24 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant.
Biochemistry, 36, 1997
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8HKQ
 | | ion channel | | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | | 著者 | Jiang, D.H, Zhang, J.T. | | 登録日 | 2022-11-27 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
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8HKK
 | | ion channel | | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | | 著者 | Jiang, D.H, Zhang, J.T. | | 登録日 | 2022-11-27 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
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8HIR
 | | potassium channels | | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ... | | 著者 | Jiang, D.H, Zhang, J.T. | | 登録日 | 2022-11-21 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
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8HKM
 | | ion channel | | 分子名称: | POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION, ... | | 著者 | Jiang, D.H, Zhang, J.T. | | 登録日 | 2022-11-27 | | 公開日 | 2023-08-16 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
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