1G5M
| HUMAN BCL-2, ISOFORM 1 | 分子名称: | PROTEIN (APOPTOSIS REGULATOR BCL-2 WITH PUTATIVE FLEXIBLE LOOP REPLACED WITH A PORTION OF APOPTOSIS REGULATOR BCL-X PROTEIN) | 著者 | Petros, A.M, Medek, A, Nettesheim, D.G, Kim, D.H, Yoon, H.S, Swift, K, Matayoshi, E.D, Oltersdorf, T, Fesik, S.W. | 登録日 | 2000-11-01 | 公開日 | 2001-03-21 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the antiapoptotic protein bcl-2. Proc.Natl.Acad.Sci.USA, 98, 2001
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1G67
| THIAMIN PHOSPHATE SYNTHASE | 分子名称: | 2-METHYL-5-METHYLENE-5H-PYRIMIDIN-4-YLIDENEAMINE, 4-METHYL-5-HYDROXYETHYLTHIAZOLE PHOSPHATE, MAGNESIUM ION, ... | 著者 | Peapus, D.H, Chiu, H.-J, Campobasso, N, Reddick, J.J, Begley, T.P, Ealick, S.E. | 登録日 | 2000-11-03 | 公開日 | 2001-09-26 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase. Biochemistry, 40, 2001
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1U0L
| Crystal structure of YjeQ from Thermotoga maritima | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Probable GTPase engC, ZINC ION | 著者 | Shin, D.H, Lou, Y, Jaru, J, Kim, R, Yokota, H, Kim, S.H, Berkeley Structural Genomics Center (BSGC) | 登録日 | 2004-07-13 | 公開日 | 2004-09-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of YjeQ from Thermotoga maritima contains a circularly permuted GTPase domain Proc.Natl.Acad.Sci.Usa, 101, 2004
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1U3H
| Crystal structure of mouse TCR 172.10 complexed with MHC class II I-Au molecule at 2.4 A | 分子名称: | H-2 class II histocompatibility antigen, A-U alpha chain, A-U beta chain, ... | 著者 | Maynard, J, Petersson, K, Wilson, D.H, Adams, E.J, Blondelle, S.E, Boulanger, M.J, Wilson, D.B, Garcia, K.C. | 登録日 | 2004-07-21 | 公開日 | 2005-05-17 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity Immunity, 22, 2005
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8JIP
| Cryo-EM structure of the GLP-1R/GCGR dual agonist MEDI0382-bound human GLP-1R-Gs complex | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | 登録日 | 2023-05-27 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.85 Å) | 主引用文献 | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIR
| Cryo-EM structure of the GLP-1R/GCGR dual agonist SAR425899-bound human GLP-1R-Gs complex | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | 登録日 | 2023-05-27 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIT
| Cryo-EM structure of the GLP-1R/GCGR dual agonist MEDI0382-bound human GCGR-Gs complex | 分子名称: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | 登録日 | 2023-05-27 | 公開日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIQ
| Cryo-EM structure of the GLP-1R/GCGR dual agonist Peptide 15-bound human GCGR-Gs complex | 分子名称: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | 登録日 | 2023-05-27 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIU
| Cryo-EM structure of the GLP-1R/GCGR dual agonist SAR425899-bound human GCGR-Gs complex | 分子名称: | Glucagon receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | 登録日 | 2023-05-27 | 公開日 | 2023-09-13 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ITM
| Cryo-EM structure of GIPR splice variant 2 (SV2) in complex with Gs protein | 分子名称: | Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, F.H, Hang, K.N, Zhou, Q.T, Shao, L.J, Li, H, Li, W.Z, Lin, S, Dai, A.T, Cai, X.Q, Liu, Y.Y, Xu, Y.N, Feng, W.B, Yang, D.H, Wang, M.W. | 登録日 | 2023-03-22 | 公開日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Molecular basis of signal transduction mediated by the human GIPR splice variants. Proc.Natl.Acad.Sci.USA, 120, 2023
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8ITL
| Cryo-EM structure of GIPR splice variant 1 (SV1) in complex with Gs protein | 分子名称: | Gastric inhibitory polypeptide receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhao, F.H, Hang, K.N, Zhou, Q.T, Shao, L.J, Li, H, Li, W.Z, Lin, S, Dai, A.T, Cai, X.Q, Liu, Y.Y, Xu, Y.N, Feng, W.B, Yang, D.H, Wang, M.W. | 登録日 | 2023-03-22 | 公開日 | 2023-10-18 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | Molecular basis of signal transduction mediated by the human GIPR splice variants. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIS
| Cryo-EM structure of the GLP-1R/GCGR dual agonist peptide15-bound human GLP-1R-Gs complex | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Yang, L, Zhou, Q.T, Dai, A.T, Zhao, F.H, Chang, R.L, Ying, T.L, Wu, B.L, Yang, D.H, Wang, M.W, Cong, Z.T. | 登録日 | 2023-05-27 | 公開日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | 主引用文献 | Structural analysis of the dual agonism at GLP-1R and GCGR. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JCE
| Cryo-EM Structure of Chikungunya Virus Nonstructural Protein 1 with m7GpppAmU | 分子名称: | MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION, ... | 著者 | Zhang, K, Law, M.C.Y, Nguyen, T.M, Tan, Y.B, Wirawan, M, Law, Y.S, Luo, D.H. | 登録日 | 2023-05-11 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Chikungunya virus nonstructural protein 1 is a versatile RNA capping and decapping enzyme. J.Biol.Chem., 299, 2023
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3TTN
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3TTM
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3V52
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | 1,2-ETHANEDIOL, ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, ... | 著者 | Mage, M.G, Dolan, M.A, Wang, R, Boyd, L.F, Revilleza, M.J, Robinson, H, Natarajan, K, Myers, N.B, Hansen, T.H, Margulies, D.H. | 登録日 | 2011-12-15 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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8J7H
| ion channel | 分子名称: | ILE-ALA-ALA-ILE-HIS-ASN-ALA-ARG-ARG-LYS-LYS-ARG-GLU-ALA-ALA-ALA-ALA-HIS-LYS-ALA, ion channel | 著者 | Chen, H.W, Jiang, D.H. | 登録日 | 2023-04-27 | 公開日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | ion channel To Be Published
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8J6O
| transport T2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Green fluorescent protein (Fragment),SID1 transmembrane family member 2, ... | 著者 | Jiang, D.H, Zhang, J.T. | 登録日 | 2023-04-26 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insights into double-stranded RNA recognition and transport by SID-1. Nat.Struct.Mol.Biol., 31, 2024
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8J6M
| SIDT1 protein | 分子名称: | CHOLESTEROL, Green fluorescent protein,SID1 transmembrane family member 1, OLEIC ACID, ... | 著者 | Zhang, J.T, Jiang, D.H. | 登録日 | 2023-04-26 | 公開日 | 2024-05-01 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structural insights into double-stranded RNA recognition and transport by SID-1. Nat.Struct.Mol.Biol., 31, 2024
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3UYR
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | 1,2-ETHANEDIOL, H-2 class I histocompatibility antigen, L-D alpha chain, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-12-06 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3VW7
| Crystal structure of human protease-activated receptor 1 (PAR1) bound with antagonist vorapaxar at 2.2 angstrom | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CHLORIDE ION, Proteinase-activated receptor 1, ... | 著者 | Zhang, C, Srinivasan, Y, Arlow, D.H, Fung, J.J, Palmer, D, Zheng, Y, Green, H.F, Pandey, A, Dror, R.O, Shaw, D.E, Weis, W.I, Coughlin, S.R, Kobilka, B.K. | 登録日 | 2012-08-07 | 公開日 | 2012-12-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | High-resolution crystal structure of human protease-activated receptor 1 Nature, 492, 2012
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3V4U
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-12-15 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3UO1
| Structure of a monoclonal antibody complexed with its MHC-I antigen | 分子名称: | ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN, 64-3-7 L CHAIN, ... | 著者 | Margulies, D.H, Mage, M.G, Wang, R, Natarajan, K. | 登録日 | 2011-11-16 | 公開日 | 2012-07-25 | 最終更新日 | 2012-08-01 | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | 主引用文献 | The Peptide-receptive transition state of MHC class I molecules: insight from structure and molecular dynamics. J.Immunol., 189, 2012
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3TM0
| Crystal Structure of 3',5"-Aminoglycoside Phosphotransferase Type IIIa AMPPNP Butirosin A Complex | 分子名称: | (2S)-4-amino-N-[(1R,2S,3R,4R,5S)-5-amino-4-[(2,6-diamino-2,6-dideoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxy-3-(beta-D-xylofuranosyloxy)cyclohexyl]-2-hydroxybutanamide, Aminoglycoside 3'-phosphotransferase, MAGNESIUM ION, ... | 著者 | Berghuis, A.M, Fong, D.H. | 登録日 | 2011-08-30 | 公開日 | 2011-10-19 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis of APH(3')-IIIa-mediated resistance to N1-substituted aminoglycoside antibiotics. Antimicrob.Agents Chemother., 53, 2009
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3TTK
| Crystal structure of apo-SpuD | 分子名称: | Polyamine transport protein | 著者 | Wu, D.H, Lim, S.C, Song, H.W. | 登録日 | 2011-09-14 | 公開日 | 2012-03-28 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | 主引用文献 | Structural Basis of Substrate Binding Specificity Revealed by the Crystal Structures of Polyamine Receptors SpuD and SpuE from Pseudomonas aeruginosa J.Mol.Biol., 416, 2012
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