2O1W
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2O8K
| NMR Structure of the Sigma-54 RpoN Domain Bound to the-24 Promoter Element | Descriptor: | 5'-D(*GP*AP*AP*AP*CP*GP*TP*GP*CP*CP*AP*AP*AP*A)-3', 5'-D(*TP*TP*TP*TP*GP*GP*CP*AP*CP*GP*TP*TP*TP*C)-3', RNA polymerase sigma factor RpoN | Authors: | Doucleff, M, Pelton, J.G, Lee, P.S, Wemmer, D.E. | Deposit date: | 2006-12-12 | Release date: | 2007-07-17 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structural basis of DNA recognition by the alternative sigma-factor, sigma54. J.Mol.Biol., 369, 2007
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2OGZ
| Crystal structure of DPP-IV complexed with Lilly aryl ketone inhibitor | Descriptor: | 4-[(3R)-3-{[2-(4-FLUOROPHENYL)-2-OXOETHYL]AMINO}BUTYL]BENZAMIDE, Dipeptidyl peptidase | Authors: | Timm, D.E. | Deposit date: | 2007-01-09 | Release date: | 2007-03-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site. Bioorg.Med.Chem.Lett., 17, 2007
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2NC4
| Solution Structure of N-Galactosylated Pin1 WW Domain | Descriptor: | Pin1 WW Domain, beta-D-galactopyranose | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | Deposit date: | 2016-03-20 | Release date: | 2016-06-08 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. J.Am.Chem.Soc., 138, 2016
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2P4E
| Crystal Structure of PCSK9 | Descriptor: | MERCURY (II) ION, Proprotein convertase subtilisin/kexin type 9 | Authors: | Cunningham, D, Danley, D.E, Geoghegan, F.K, Griffor, M.C, Hawkins, J.L, Qiu, X. | Deposit date: | 2007-03-12 | Release date: | 2007-04-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia. Nat.Struct.Mol.Biol., 14, 2007
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2P51
| Crystal structure of the S. pombe Pop2p deadenylation subunit | Descriptor: | MAGNESIUM ION, SPCC18.06c protein | Authors: | Thyssen Jonstrup, A, Andersen, K.R, Van, L.B, Brodersen, D.E. | Deposit date: | 2007-03-14 | Release date: | 2007-05-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The 1.4-A crystal structure of the S. pombe Pop2p deadenylase subunit unveils the configuration of an active enzyme Nucleic Acids Res., 35, 2007
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2PC0
| Apo Wild-type HIV Protease in the open conformation | Descriptor: | MAGNESIUM ION, Protease, R-1,2-PROPANEDIOL | Authors: | Heaslet, H, Rosenfeld, R, Giffin, M.J, Elder, J.H, McRee, D.E, Stout, C.D. | Deposit date: | 2007-03-29 | Release date: | 2007-06-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Conformational flexibility in the flap domains of ligand-free HIV protease. Acta Crystallogr.,Sect.D, 63, 2007
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2NP8
| Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors | Descriptor: | N-{3-[(4-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}PYRIMIDIN-2-YL)AMINO]PHENYL}CYCLOPROPANECARBOXAMIDE, SULFATE ION, Serine/threonine-protein kinase 6 | Authors: | Tari, L.W, Hoffman, I.D, Bensen, D.C, Hunter, M.J, Nix, J, Nelson, K.J, McRee, D.E, Swanson, R.V. | Deposit date: | 2006-10-26 | Release date: | 2006-12-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors. Bioorg.Med.Chem.Lett., 17, 2007
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2NC5
| Solution Structure of N-Xylosylated Pin1 WW Domain | Descriptor: | Pin1 WW Domain, beta-D-xylopyranose | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | Deposit date: | 2016-03-20 | Release date: | 2016-06-08 | Last modified: | 2020-07-29 | Method: | SOLUTION NMR | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. J.Am.Chem.Soc., 138, 2016
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2NC3
| Solution Structure of N-Allosylated Pin1 WW Domain | Descriptor: | Pin1 WW Domain, beta-D-allopyranose | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | Deposit date: | 2016-03-20 | Release date: | 2016-06-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. J.Am.Chem.Soc., 138, 2016
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2PS7
| Y295F trichodiene synthase | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Trichodiene synthase | Authors: | Vedula, L.S, Cane, D.E, Christianson, D.W. | Deposit date: | 2007-05-04 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif. Arch.Biochem.Biophys., 469, 2008
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2PIS
| Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs | Descriptor: | DNA (5'-D(*CP*GP*(CBR)P*GP*AP*AP*(FFD)P*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | Authors: | Matsuda, S, Fillo, J.D, Henry, A.A, Wilkins, S.J, Rai, P, Dwyer, T.J, Geierstanger, B.H, Wemmer, D.E, Schultz, P.G, Spraggon, G, Romesberg, F.E. | Deposit date: | 2007-04-13 | Release date: | 2007-10-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs. J.Am.Chem.Soc., 129, 2007
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2PMW
| The Crystal Structure of Proprotein convertase subtilisin kexin type 9 (PCSK9) | Descriptor: | Proprotein convertase subtilisin/kexin type 9, SULFATE ION | Authors: | Piper, D.E, Romanow, W.G, Thibault, S.T, Walker, N.P.C. | Deposit date: | 2007-04-23 | Release date: | 2007-05-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol. Structure, 15, 2007
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2PS6
| N225D/S229T trichodiene synthase | Descriptor: | 1,2-ETHANEDIOL, Trichodiene synthase | Authors: | Vedula, L.S, Cane, D.E, Christianson, D.W. | Deposit date: | 2007-05-04 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif. Arch.Biochem.Biophys., 469, 2008
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2PS4
| N225D trichodiene synthase | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Trichodiene synthase | Authors: | Vedula, L.S, Cane, D.E, Christianson, D.W. | Deposit date: | 2007-05-04 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif. Arch.Biochem.Biophys., 469, 2008
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2PS5
| N225D Trichodiene Synthase: Complex With Mg and Pyrophosphate | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | Authors: | Vedula, L.S, Cane, D.E, Christianson, D.W. | Deposit date: | 2007-05-04 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif. Arch.Biochem.Biophys., 469, 2008
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2PYP
| PHOTOACTIVE YELLOW PROTEIN, PHOTOSTATIONARY STATE, 50% GROUND STATE, 50% BLEACHED | Descriptor: | 4'-HYDROXYCINNAMIC ACID, PHOTOACTIVE YELLOW PROTEIN | Authors: | Genick, U.K, Borgstahl, G.E.O, Ng, K, Ren, Z, Pradervand, C, Burke, P, Srajer, V, Teng, T, Schildkamp, W, Mcree, D.E, Moffat, K, Getzoff, E.D. | Deposit date: | 1997-02-03 | Release date: | 1998-04-29 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of a protein photocycle intermediate by millisecond time-resolved crystallography. Science, 275, 1997
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2L4K
| Water refined solution structure of the human Grb7-SH2 domain in complex with the 10 amino acid peptide pY1139 | Descriptor: | Growth factor receptor-bound protein 7, Receptor tyrosine-protein kinase erbB-2 | Authors: | Pias, S.C, Ivancic, M, Brescia, P.J, Johnson, D.L, Smith, D.E, Daly, R.J, Lyons, B.A. | Deposit date: | 2010-10-07 | Release date: | 2010-11-17 | Last modified: | 2012-10-03 | Method: | SOLUTION NMR | Cite: | Water-Refined Solution Structure of the Human Grb7-SH2 Domain in Complex with the erbB2 Receptor Peptide pY1139. Protein Pept.Lett., 19, 2012
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2LL7
| Solution NMR structure of CaM bound to the eNOS CaM binding domain peptide | Descriptor: | Calmodulin, Nitric oxide synthase, endothelial | Authors: | Piazza, M, Futrega, K, Spratt, D.E, Guillemette, J.G, Dieckmann, T. | Deposit date: | 2011-10-29 | Release date: | 2012-05-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure and Dynamics of Calmodulin (CaM) Bound to Nitric Oxide Synthase Peptides: Effects of a Phosphomimetic CaM Mutation. Biochemistry, 51, 2012
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2LT8
| Eurocin solution structure | Descriptor: | eurocin | Authors: | Oeemig, J.S, Lynggaard, C, Knudsen, D.H, Hansen, F.T, Noergaard, K.D, Schneider, T, Vad, B.S, Neve, S, Kristensen, H, Sahl, H, Otzen, D.E, Wimmer, R. | Deposit date: | 2012-05-15 | Release date: | 2012-10-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Eurocin, a New Fungal Defensin: STRUCTURE, LIPID BINDING, AND ITS MODE OF ACTION. J.Biol.Chem., 287, 2012
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2NC6
| Solution Structure of N-L-idosylated Pin1 WW Domain | Descriptor: | Pin1 WW Domain, beta-L-idopyranose | Authors: | Hsu, C, Park, S, Mortenson, D.E, Foley, B, Wang, X, Woods, R.J, Case, D.A, Powers, E.T, Wong, C, Dyson, H, Kelly, J.W. | Deposit date: | 2016-03-20 | Release date: | 2016-06-08 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. J.Am.Chem.Soc., 138, 2016
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2PS8
| Y295F Trichodiene Synthase: Complex With Mg and Pyrophosphate | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | Authors: | Vedula, L.S, Cane, D.E, Christianson, D.W. | Deposit date: | 2007-05-04 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif. Arch.Biochem.Biophys., 469, 2008
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2PSR
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2Q9Y
| Trichodiene synthase: Complex with Mg, inorganic pyrophosphate, and benzyl triethyl ammonium cation | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, N-benzyl-N,N-diethylethanaminium, ... | Authors: | Vedula, L.S, Zhao, Y, Coates, R.M, Koyama, T, Cane, D.E, Christianson, D.W. | Deposit date: | 2007-06-14 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Exploring biosynthetic diversity with trichodiene synthase. Arch.Biochem.Biophys., 466, 2007
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