2XFP
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![BU of 2xfp by Molmil](/molmil-images/mine/2xfp) | Isatin-inhibited human monoamine oxidase B in complex with 2-(2- benzofuranyl)-2-imidazoline | Descriptor: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-05-26 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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3Q1F
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![BU of 3q1f by Molmil](/molmil-images/mine/3q1f) | CTX-M-9 S70G in complex with hydrolyzed piperacillin | Descriptor: | Beta-lactamase, Hydrolyzed piperacillin | Authors: | Leyssne, D, Delmas, J, Coignoux, A, Robin, F, Bonnet, R. | Deposit date: | 2010-12-17 | Release date: | 2011-12-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | CTX-M-9 S70G mutant in complex with hydrolyzed piperacillin To be Published
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2XI3
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![BU of 2xi3 by Molmil](/molmil-images/mine/2xi3) | HCV-H77 NS5B Polymerase Complexed With GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA-directed RNA polymerase | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | Deposit date: | 2010-06-25 | Release date: | 2010-08-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2XCZ
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![BU of 2xcz by Molmil](/molmil-images/mine/2xcz) | Crystal Structure of macrophage migration inhibitory factor homologue from Prochlorococcus marinus | Descriptor: | DI(HYDROXYETHYL)ETHER, POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN | Authors: | Wasiel, A.A, Rozeboom, H.J, Hauke, D, Baas, B.J, Zandvoort, E, Quax, W.J, Thunnissen, A.M.W.H, Poelarends, G.J. | Deposit date: | 2010-04-27 | Release date: | 2010-09-01 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Structural and Functional Characterization of a Macrophage Migration Inhibitory Factor Homologue from the Marine Cyanobacterium Prochlorococcus Marinus. Biochemistry, 49, 2010
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2XBS
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![BU of 2xbs by Molmil](/molmil-images/mine/2xbs) | Raman crystallography of Hen White Egg Lysozyme - High X-ray dose (16 MGy) | Descriptor: | CHLORIDE ION, LYSOZYME C | Authors: | Carpentier, P, Royant, A, Weik, M, Bourgeois, D. | Deposit date: | 2010-04-14 | Release date: | 2010-11-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.37 Å) | Cite: | Raman Assisted Crystallography Reveals a Mechanism of X-Ray Induced Reversible Disulfide Radical Formation Structure, 18, 2010
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2XFS
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![BU of 2xfs by Molmil](/molmil-images/mine/2xfs) | Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway | Descriptor: | (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, ORF12 | Authors: | Iqbal, A, Valegard, K, Kershaw, N.J, Ivison, D, Genereux, C, Dubus, A, Andersson, I, Schofield, C.J. | Deposit date: | 2010-05-26 | Release date: | 2011-06-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway. Acta Crystallogr. D Biol. Crystallogr., 69, 2013
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2XCG
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![BU of 2xcg by Molmil](/molmil-images/mine/2xcg) | Tranylcypromine-inhibited human monoamine oxidase B in complex with 2- (2-benzofuranyl)-2-imidazoline | Descriptor: | 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, 3-PHENYLPROPANAL, Amine oxidase [flavin-containing] B, ... | Authors: | Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. | Deposit date: | 2010-04-23 | Release date: | 2010-10-06 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
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1P45
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![BU of 1p45 by Molmil](/molmil-images/mine/1p45) | Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | Authors: | Kuo, M.R, Morbidoni, H.R, Alland, D, Sneddon, S.F, Gourlie, B.B, Staveski, M.M, Leonard, M, Gregory, J.S, Janjigian, A.D, Yee, C, Musser, J.M, Kreiswirth, B.N, Iwamoto, H, Perozzo, R, Jacobs Jr, W.R, Sacchettini, J.C, Fidock, D.A, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-04-21 | Release date: | 2003-09-16 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data. J.Biol.Chem., 278, 2003
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1OP9
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![BU of 1op9 by Molmil](/molmil-images/mine/1op9) | Complex of human lysozyme with camelid VHH HL6 antibody fragment | Descriptor: | HL6 camel VHH fragment, Lysozyme C | Authors: | Dumoulin, M, Last, A.M, Desmyter, A, Decanniere, K, Canet, D, Larsson, G, Spencer, A, Archer, D.B, Sasse, J, Muyldermans, S, Wyns, L, Redfield, C, Matagne, A, Robinson, C.V, Dobson, C.M. | Deposit date: | 2003-03-05 | Release date: | 2003-10-14 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme Nature, 424, 2003
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2XHV
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![BU of 2xhv by Molmil](/molmil-images/mine/2xhv) | HCV-J4 NS5B Polymerase Point Mutant Orthorhombic Crystal Form | Descriptor: | MAGNESIUM ION, RNA-directed RNA polymerase, SULFATE ION | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | Deposit date: | 2010-06-21 | Release date: | 2010-08-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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1P64
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![BU of 1p64 by Molmil](/molmil-images/mine/1p64) | T4 LYSOZYME CORE REPACKING MUTANT L133F/TA | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... | Authors: | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | Deposit date: | 2003-04-28 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Repacking the Core of T4 lysozyme by automated design J.Mol.Biol., 332, 2003
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2XI2
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![BU of 2xi2 by Molmil](/molmil-images/mine/2xi2) | HCV-H77 NS5B Apo Polymerase | Descriptor: | RNA-directed RNA polymerase, SULFATE ION | Authors: | Harrus, D, Ahmed-El-Sayed, N, Simister, P.C, Miller, S, Triconnet, M, Hagedorn, C.H, Mahias, K, Rey, F.A, Astier-Gin, T, Bressanelli, S. | Deposit date: | 2010-06-25 | Release date: | 2010-08-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Further Insights Into the Roles of GTP and the C- Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis J.Biol.Chem., 285, 2010
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2V30
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![BU of 2v30 by Molmil](/molmil-images/mine/2v30) | Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP. | Descriptor: | OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE | Authors: | Moche, M, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Welin, M, Nordlund, P, Structural Genomics Consortium (SGC) | Deposit date: | 2007-06-10 | Release date: | 2007-07-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Crystal Structure of Human Orotidine 5'-Decarboxylase Domain of Human Uridine Monophosphate Synthetase (Umps) To be Published
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1OUQ
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![BU of 1ouq by Molmil](/molmil-images/mine/1ouq) | Crystal structure of wild-type Cre recombinase-loxP synapse | Descriptor: | Cre recombinase, IODIDE ION, MAGNESIUM ION, ... | Authors: | Ennifar, E, Meyer, J.E.W, Buchholz, F, Stewart, A.F, Suck, D. | Deposit date: | 2003-03-25 | Release date: | 2003-09-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation Nucleic Acids Res., 31, 2003
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2VCP
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![BU of 2vcp by Molmil](/molmil-images/mine/2vcp) | Crystal structure of N-Wasp VC domain in complex with skeletal actin | Descriptor: | ACTIN, ALPHA SKELETAL MUSCLE, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Gaucher, J.F, Didry, D, Carlier, M.F. | Deposit date: | 2007-09-26 | Release date: | 2008-11-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Interactions of isolated C-terminal fragments of neural Wiskott-Aldrich syndrome protein (N-WASP) with actin and Arp2/3 complex. J. Biol. Chem., 287, 2012
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4B8T
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![BU of 4b8t by Molmil](/molmil-images/mine/4b8t) | RNA BINDING PROTEIN Solution structure of the third KH domain of KSRP in complex with the G-rich target sequence. | Descriptor: | 5'-R(*AP*GP*GP*GP*UP)-3', KH-TYPE SPLICING REGULATORY PROTEIN | Authors: | Nicastro, G, Garcia-Mayoral, M.F, Hollingworth, D, Kelly, G, Martin, S.R, Briata, P, Gherzi, R, Ramos, A. | Deposit date: | 2012-08-30 | Release date: | 2012-11-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Noncanonical G Recognition Mediates Ksrp Regulation of Let-7 Biogenesis Nat.Struct.Mol.Biol., 19, 2012
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2V9O
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![BU of 2v9o by Molmil](/molmil-images/mine/2v9o) | |
2VH2
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![BU of 2vh2 by Molmil](/molmil-images/mine/2vh2) | Crystal structure of cell divison protein FtsQ from Yersinia enterecolitica | Descriptor: | CELL DIVISION PROTEIN FTSQ | Authors: | van den Ent, F, Vinkenvleugel, T, Ind, A, West, P, Veprintsev, D, Nanninga, N, den Blaauwen, T, Lowe, J. | Deposit date: | 2007-11-16 | Release date: | 2008-03-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural and Mutational Analysis of Cell Division Protein Ftsq Mol.Microbiol., 68, 2008
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3PHU
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![BU of 3phu by Molmil](/molmil-images/mine/3phu) | OTU Domain of Crimean Congo Hemorrhagic Fever Virus | Descriptor: | GLYCEROL, RNA-directed RNA polymerase L | Authors: | Akutsu, M, Ye, Y, Virdee, S, Komander, D. | Deposit date: | 2010-11-04 | Release date: | 2011-02-02 | Last modified: | 2014-11-12 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains. Proc.Natl.Acad.Sci.USA, 108, 2011
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1P2L
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![BU of 1p2l by Molmil](/molmil-images/mine/1p2l) | T4 Lysozyme Core Repacking Mutant V87I/TA | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... | Authors: | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | Deposit date: | 2003-04-15 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Repacking the Core of T4 lysozyme by automated design J.Mol.Biol., 332, 2003
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1OKD
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![BU of 1okd by Molmil](/molmil-images/mine/1okd) | NMR-structure of tryparedoxin 1 | Descriptor: | TRYPAREDOXIN 1 | Authors: | Krumme, D, Budde, H, Hecht, H.-J, Menge, U, Ohlenschlager, O, Ross, A, Wissing, J, Wray, V, Flohe, L. | Deposit date: | 2003-07-22 | Release date: | 2003-08-28 | Last modified: | 2018-01-17 | Method: | SOLUTION NMR | Cite: | NMR studies of the interaction of tryparedoxin with redox-inactive substrate homologues. Biochemistry, 42, 2003
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2UV3
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![BU of 2uv3 by Molmil](/molmil-images/mine/2uv3) | Structure of the signal-regulatory protein (SIRP) alpha domain that binds CD47. | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | Authors: | Hatherley, D, Harlos, K, Dunlop, D.C, Stuart, D.I, Barclay, A.N. | Deposit date: | 2007-03-08 | Release date: | 2007-03-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Structure of the Macrophage Signal Regulatory Protein Alpha (Sirpalpha) Inhibitory Receptor Reveals a Binding Face Reminiscent of that Used by T Cell Receptors. J.Biol.Chem., 282, 2007
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2VFL
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![BU of 2vfl by Molmil](/molmil-images/mine/2vfl) | AKAP18 delta central domain - CMP | Descriptor: | AKAP18 DELTA, CYTIDINE-5'-MONOPHOSPHATE | Authors: | Gold, M.G, Smith, F.D, Scott, J.D, Barford, D. | Deposit date: | 2007-11-05 | Release date: | 2008-05-06 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Akap18 Contains a Phosphoesterase Domain that Binds AMP J.Mol.Biol., 375, 2008
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1QI6
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![BU of 1qi6 by Molmil](/molmil-images/mine/1qi6) | SECOND APO FORM OF AN NADP DEPENDENT ALDEHYDE DEHYDROGENASE WITH GLU250 SITUATED 3.7 A FROM CYS284 | Descriptor: | PROTEIN (NADP DEPENDENT NONPHOSPHORYLATING GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), SULFATE ION | Authors: | Cobessi, D, Tete-Favier, F, Marchal, S, Branlant, G, Aubry, A. | Deposit date: | 1999-06-02 | Release date: | 2001-01-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and biochemical investigations of the catalytic mechanism of an NADP-dependent aldehyde dehydrogenase from Streptococcus mutans. J.Mol.Biol., 300, 2000
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1Q74
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![BU of 1q74 by Molmil](/molmil-images/mine/1q74) | The Crystal Structure of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB) | Descriptor: | 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB), 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ZINC ION | Authors: | Maynes, J.T, Garen, C, Cherney, M.M, Newton, G, Arad, D, Av-Gay, Y, Fahey, R.C, James, M.N, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2003-08-15 | Release date: | 2003-12-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Crystal Structure of 1-D-myo-Inositol 2-Acetamido-2-deoxy-alpha-D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold. J.Biol.Chem., 278, 2003
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