4RHU
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![BU of 4rhu by Molmil](/molmil-images/mine/4rhu) | Crystal structures of Mycobacterium tuberculosis 6-oxopurine phosphoribosyltransferase which is a potential target for drug development against this disease | Descriptor: | Hypoxanthine-guanine phosphoribosyltransferase Hpt, MAGNESIUM ION, {[(2R)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid), ... | Authors: | Eng, W.S, Hockova, D, Spacek, P, West, N.P, Woods, K, Naesens, L.M.J, Keough, D.T, Guddat, L.W. | Deposit date: | 2014-10-03 | Release date: | 2015-05-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.573 Å) | Cite: | First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity. J.Med.Chem., 58, 2015
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4RJK
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![BU of 4rjk by Molmil](/molmil-images/mine/4rjk) | Acetolactate synthase from Bacillus subtilis bound to LThDP - crystal form II | Descriptor: | 3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-(1-CARBOXY-1-HYDROXYETHYL)-5-(2-{[HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM, Acetolactate synthase, MAGNESIUM ION, ... | Authors: | Sommer, B, von Moeller, H, Haack, M, Qoura, F, Langner, C, Bourenkov, G, Garbe, D, Brueck, T, Loll, B. | Deposit date: | 2014-10-09 | Release date: | 2014-10-22 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Detailed Structure-Function Correlations of Bacillus subtilis Acetolactate Synthase. Chembiochem, 16, 2015
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4RJI
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![BU of 4rji by Molmil](/molmil-images/mine/4rji) | Acetolactate synthase from Bacillus subtilis bound to ThDP - crystal form I | Descriptor: | Acetolactate synthase, MAGNESIUM ION, TETRAETHYLENE GLYCOL, ... | Authors: | Sommer, B, von Moeller, H, Haack, M, Qoura, F, Langner, C, Bourenkov, G, Garbe, D, Brueck, T, Loll, B. | Deposit date: | 2014-10-09 | Release date: | 2014-10-22 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Detailed Structure-Function Correlations of Bacillus subtilis Acetolactate Synthase. Chembiochem, 16, 2015
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4RJJ
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![BU of 4rjj by Molmil](/molmil-images/mine/4rjj) | Acetolactate synthase from Bacillus subtilis bound to ThDP - crystal form II | Descriptor: | ACETATE ION, Acetolactate synthase, MAGNESIUM ION, ... | Authors: | Sommer, B, von Moeller, H, Haack, M, Qoura, F, Langner, C, Bourenkov, G, Garbe, D, Brueck, T, Loll, B. | Deposit date: | 2014-10-09 | Release date: | 2014-10-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Detailed Structure-Function Correlations of Bacillus subtilis Acetolactate Synthase. Chembiochem, 16, 2015
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4RJE
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![BU of 4rje by Molmil](/molmil-images/mine/4rje) | Aerococcus viridans L-lactate oxidase mutant | Descriptor: | 1,2-ETHANEDIOL, 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, Lactate oxidase, ... | Authors: | Rainer, D, Nidetzky, B, Wilson, D.K. | Deposit date: | 2014-10-08 | Release date: | 2014-12-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The Ala95-to-Gly substitution in Aerococcus viridans l-lactate oxidase revisited - structural consequences at the catalytic site and effect on reactivity with O2 and other electron acceptors. Febs J., 282, 2015
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4RTD
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![BU of 4rtd by Molmil](/molmil-images/mine/4rtd) | Escherichia coli alpha-2-macroglobulin activated by porcine elastase | Descriptor: | Uncharacterized lipoprotein YfhM | Authors: | Fyfe, C.D, Grinter, R, Roszak, A.W, Josts, I, Cogdell, R.J, Walker, D. | Deposit date: | 2014-11-14 | Release date: | 2015-07-15 | Last modified: | 2015-07-29 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structure of protease-cleaved Escherichia coli alpha-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment. Acta Crystallogr.,Sect.D, 71, 2015
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4RWH
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![BU of 4rwh by Molmil](/molmil-images/mine/4rwh) | Crystal structure of T cell costimulatory ligand B7-1 (CD80) | Descriptor: | T-lymphocyte activation antigen CD80 | Authors: | Fedorov, A.A, Fedorov, E.V, Samanta, D, Hillerich, B, Seidel, R.D, Almo, S.C. | Deposit date: | 2014-12-04 | Release date: | 2014-12-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Crystal structure of T cell costimulatory ligand B7-1 (CD80) To be Published
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4NTF
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![BU of 4ntf by Molmil](/molmil-images/mine/4ntf) | |
4TLU
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![BU of 4tlu by Molmil](/molmil-images/mine/4tlu) | |
4NWQ
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![BU of 4nwq by Molmil](/molmil-images/mine/4nwq) | Computationally Designed Two-Component Self-Assembling Tetrahedral Cage, T33-21, Crystallized in Space Group F4132 | Descriptor: | Putative uncharacterized protein PH0671, SULFATE ION, Uncharacterized protein | Authors: | McNamara, D.E, King, N.P, Bale, J.B, Sheffler, W, Baker, D, Yeates, T.O. | Deposit date: | 2013-12-06 | Release date: | 2014-05-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Accurate design of co-assembling multi-component protein nanomaterials. Nature, 510, 2014
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4TNG
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![BU of 4tng by Molmil](/molmil-images/mine/4tng) | |
4PI7
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![BU of 4pi7 by Molmil](/molmil-images/mine/4pi7) | Crystal structure of S. Aureus Autolysin E in complex with disaccharide NAM-NAG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid, Autolysin E, CHLORIDE ION, ... | Authors: | Mihelic, M, Renko, M, Jakas, A, Turk, D. | Deposit date: | 2014-05-08 | Release date: | 2015-10-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The mechanism behind the selection of two different cleavage sites in NAG-NAM polymers Iucrj, 4, 2017
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4PIA
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![BU of 4pia by Molmil](/molmil-images/mine/4pia) | Crystal structure of S. Aureus Autolysin E | Descriptor: | Autolysin E, CHLORIDE ION | Authors: | Mihelic, M, Renko, M, Dobersek, A, Bedrac, L, Turk, D. | Deposit date: | 2014-05-08 | Release date: | 2015-10-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.466 Å) | Cite: | The mechanism behind the selection of two different cleavage sites in NAG-NAM polymers Iucrj, 4, 2017
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4NEX
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![BU of 4nex by Molmil](/molmil-images/mine/4nex) | Structure of the N-acetyltransferase domain of X. fastidiosa NAGS/K | Descriptor: | Acetylglutamate kinase, N-ACETYL-L-GLUTAMATE, SULFATE ION | Authors: | Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M, Shi, D. | Deposit date: | 2013-10-30 | Release date: | 2014-11-12 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.6955 Å) | Cite: | Structures of the N-acetyltransferase domain of Xylella fastidiosaN-acetyl-L-glutamate synthase/kinase with and without a His tag bound to N-acetyl-L-glutamate. Acta Crystallogr F Struct Biol Commun, 71, 2015
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4PMI
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![BU of 4pmi by Molmil](/molmil-images/mine/4pmi) | Crystal structure of Rev and Rev-response-element RNA complex | Descriptor: | PHOSPHATE ION, Protein Rev, Rev-Response-Element RNA | Authors: | Jayaraman, B, Crosby, D.C, Homer, C, Ribeiro, I, Mavor, D, Frankel, A.D. | Deposit date: | 2014-05-21 | Release date: | 2014-12-24 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev-Rev response element complex. Elife, 4, 2014
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4NE7
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![BU of 4ne7 by Molmil](/molmil-images/mine/4ne7) | Crystal Structure of engineered Kumamolisin-As from Alicyclobacillus sendaiensis, Northeast Structural Genomics Consortium (NESG) Target OR367 | Descriptor: | Kumamolisin-As, ZINC ION | Authors: | Guan, R, Pultz, I.S, Siegel, J.B, Seetharaman, J, Kornhaber, G, Maglaqui, M, Mao, L, Xiao, R, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2013-10-28 | Release date: | 2013-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.497 Å) | Cite: | Northeast Structural Genomics Consortium Target OR367 To be Published
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4PG0
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![BU of 4pg0 by Molmil](/molmil-images/mine/4pg0) | Insights into Substrate and Metal Binding from the Crystal Structure of Cyanobacterial Aldehyde Deformylating Oxygenase with Substrate Bound | Descriptor: | (1S,2S)-2-nonylcyclopropanecarboxylic acid, Aldehyde decarbonylase, DIMETHYL SULFOXIDE, ... | Authors: | Buer, B.C, Paul, B, Das, D, Stuckey, J.A, Marsh, E.N.G. | Deposit date: | 2014-05-01 | Release date: | 2014-11-26 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights into substrate and metal binding from the crystal structure of cyanobacterial aldehyde deformylating oxygenase with substrate bound. Acs Chem.Biol., 9, 2014
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4MLG
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![BU of 4mlg by Molmil](/molmil-images/mine/4mlg) | Structure of RS223-Beta-xylosidase | Descriptor: | Beta-xylosidase, CALCIUM ION, SULFATE ION | Authors: | Jordan, D, Braker, J, Wagschal, K, Lee, C, Dubrovska, I, Anderson, S, Wawrzak, Z. | Deposit date: | 2013-09-06 | Release date: | 2014-09-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of RS223-Beta-xylosidase To be Published
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4PED
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![BU of 4ped by Molmil](/molmil-images/mine/4ped) | Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthes | Descriptor: | Chaperone activity of bc1 complex-like, mitochondrial, SULFATE ION | Authors: | Bingman, C.A, Smith, R, Joshi, S, Stefely, J.A, Reidenbach, A.G, Ulbrich, A, Oruganty, O, Floyd, B.J, Jochem, A, Saunders, J.M, Johnson, I.E, Wrobel, R.L, Barber, G.E, Lee, D, Li, S, Kannan, N, Coon, J.J, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) | Deposit date: | 2014-04-22 | Release date: | 2014-11-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis. Mol.Cell, 57, 2015
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4PGM
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![BU of 4pgm by Molmil](/molmil-images/mine/4pgm) | |
4PEL
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![BU of 4pel by Molmil](/molmil-images/mine/4pel) | S1C mutant of Penicillin G acylase from Kluyvera citrophila | Descriptor: | CALCIUM ION, Penicillin G acylase subunit alpha, Penicillin G acylase subunit beta | Authors: | Ramasamy, S, Chand, D, Varshney, N.K, Brannigan, J.A, Wilkinson, A.J, Suresh, C.G. | Deposit date: | 2014-04-24 | Release date: | 2015-07-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Penicillin G acylase To Be Published
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4PFZ
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![BU of 4pfz by Molmil](/molmil-images/mine/4pfz) | |
6HMA
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![BU of 6hma by Molmil](/molmil-images/mine/6hma) | Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Eyal, Z, Cimicata, G, Matzov, D, Fox, T, de Val, N, Zimmerman, E, Bashan, A, Yonath, A. | Deposit date: | 2018-09-12 | Release date: | 2018-11-14 | Last modified: | 2020-05-27 | Method: | ELECTRON MICROSCOPY (2.65 Å) | Cite: | Improved model derived from cryo-EM map of Staphylococcus aureus large ribosomal subunit To Be Published
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4PI8
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![BU of 4pi8 by Molmil](/molmil-images/mine/4pi8) | Crystal structure of catalytic mutant E138A of S. Aureus Autolysin E in complex with disaccharide NAG-NAM | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid, Autolysin E, CHLORIDE ION, ... | Authors: | Mihelic, M, Renko, M, Jakas, A, Turk, D. | Deposit date: | 2014-05-08 | Release date: | 2015-10-14 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | The mechanism behind the selection of two different cleavage sites in NAG-NAM polymers Iucrj, 4, 2017
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4MSL
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![BU of 4msl by Molmil](/molmil-images/mine/4msl) | Crystal structure of the Vps10p domain of human sortilin/NTS3 in complex with AF40431 | Descriptor: | N-[(7-hydroxy-4-methyl-2-oxo-2H-chromen-8-yl)methyl]-L-leucine, Sortilin, TETRAETHYLENE GLYCOL, ... | Authors: | Andersen, J.L, Strandbygaard, D, Thirup, S. | Deposit date: | 2013-09-18 | Release date: | 2014-02-12 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex. Acta Crystallogr.,Sect.D, 70, 2014
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