6BQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bqh by Molmil](/molmil-images/mine/6bqh) | Crystal structure of 5-HT2C in complex with ritanserin | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 5-hydroxytryptamine receptor 2C,Soluble cytochrome b562, 6-(2-{4-[bis(4-fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one, ... | Authors: | Peng, Y, McCorvy, J.D, Harpsoe, K, Lansu, K, Yuan, S, Popov, P, Qu, L, Pu, M, Che, T, Nikolajse, L.F, Huang, X.P, Wu, Y, Shen, L, Bjorn-Yoshimoto, W.E, Ding, K, Wacker, D, Han, G.W, Cheng, J, Katritch, V, Jensen, A.A, Hanson, M.A, Zhao, S, Gloriam, D.E, Roth, B.L, Stevens, R.C, Liu, Z. | Deposit date: | 2017-11-27 | Release date: | 2018-02-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | 5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology. Cell, 172, 2018
|
|
1RYG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ryg by Molmil](/molmil-images/mine/1ryg) | |
1S0D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s0d by Molmil](/molmil-images/mine/1s0d) | Crystal structure of botulinum neurotoxin type B at pH 5.5 | Descriptor: | Botulinum neurotoxin type B, CALCIUM ION, ZINC ION | Authors: | Eswaramoorthy, S, Kumaran, D, Keller, J, Swaminathan, S. | Deposit date: | 2003-12-30 | Release date: | 2004-03-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Role of metals in the biological activity of Clostridium botulinum neurotoxins Biochemistry, 43, 2004
|
|
1S3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s3q by Molmil](/molmil-images/mine/1s3q) | Crystal structures of a novel open pore ferritin from the hyperthermophilic Archaeon Archaeoglobus fulgidus | Descriptor: | ZINC ION, ferritin | Authors: | Johnson, E, Cascio, D, Sawaya, M, Schroeder, I. | Deposit date: | 2004-01-13 | Release date: | 2005-04-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of a tetrahedral open pore ferritin from the hyperthermophilic archaeon Archaeoglobus fulgidus. Structure, 13, 2005
|
|
7SXN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7sxn by Molmil](/molmil-images/mine/7sxn) | Orb2A residues 1-9 MYNKFVNFI | Descriptor: | Orb2A residues 1-9 MYNKFVNFI | Authors: | Bowler, J.T, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S. | Deposit date: | 2021-11-23 | Release date: | 2022-10-05 | Last modified: | 2024-05-22 | Method: | ELECTRON CRYSTALLOGRAPHY (1.05 Å) | Cite: | Micro-electron diffraction structure of the aggregation-driving N terminus of Drosophila neuronal protein Orb2A reveals amyloid-like beta-sheets. J.Biol.Chem., 298, 2022
|
|
1S5G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s5g by Molmil](/molmil-images/mine/1s5g) | Structure of Scallop myosin S1 reveals a novel nucleotide conformation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Risal, D, Gourinath, S, Himmel, D.M, Szent-Gyorgyi, A.G, Cohen, C. | Deposit date: | 2004-01-20 | Release date: | 2004-06-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding. Proc.Natl.Acad.Sci.Usa, 101, 2004
|
|
6BXX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bxx by Molmil](/molmil-images/mine/6bxx) | GYNGFG from low-complexity domain of hnRNPA1, residues 243-248 | Descriptor: | hnRNPA1 | Authors: | Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. | Deposit date: | 2017-12-19 | Release date: | 2018-04-04 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
|
|
1S5N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s5n by Molmil](/molmil-images/mine/1s5n) | Xylose Isomerase in Substrate and Inhibitor Michaelis States: Atomic Resolution Studies of a Metal-Mediated Hydride Shift | Descriptor: | HYDROXIDE ION, MANGANESE (II) ION, SODIUM ION, ... | Authors: | Fenn, T.D, Ringe, D, Petsko, G.A. | Deposit date: | 2004-01-21 | Release date: | 2004-02-10 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Xylose isomerase in substrate and inhibitor michaelis States: atomic resolution studies of a metal-mediated hydride shift(,). Biochemistry, 43, 2004
|
|
1S62
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s62 by Molmil](/molmil-images/mine/1s62) | Solution structure of the Escherichia coli TolA C-terminal domain | Descriptor: | TolA protein | Authors: | Deprez, C, Blanchard, L, Simorre, J.-P, Gavioli, M, Guerlesquin, F, Lazdunski, C, Lloubes, R, Marion, D. | Deposit date: | 2004-01-22 | Release date: | 2005-02-15 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of the E.coli TolA C-terminal domain reveals conformational changes upon binding to the phage g3p N-terminal domain. J.Mol.Biol., 346, 2005
|
|
1SF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sf5 by Molmil](/molmil-images/mine/1sf5) | Structure of oxidized state of the P94A mutant of amicyanin | Descriptor: | Amicyanin, COPPER (II) ION | Authors: | Carrell, C.J, Sun, D, Jiang, S, Davidson, V.L, Mathews, F.S. | Deposit date: | 2004-02-19 | Release date: | 2004-07-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural Studies of Two Mutants of Amicyanin from Paracoccus denitrificans That Stabilize the Reduced State of the Copper. Biochemistry, 43, 2004
|
|
1SFD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1sfd by Molmil](/molmil-images/mine/1sfd) | oxidized form of amicyanin mutant P94F | Descriptor: | Amicyanin, COPPER (II) ION, SULFATE ION | Authors: | Carrell, C.J, Sun, D, Jiang, S, Davidson, V.L, Mathews, F.S. | Deposit date: | 2004-02-19 | Release date: | 2004-07-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (0.99 Å) | Cite: | Structural Studies of Two Mutants of Amicyanin from Paracoccus denitrificans That Stabilize the Reduced State of the Copper. Biochemistry, 43, 2004
|
|
1S0P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s0p by Molmil](/molmil-images/mine/1s0p) | Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum. | Descriptor: | Adenylyl cyclase-associated protein, MAGNESIUM ION | Authors: | Ksiazek, D, Brandstetter, H, Israel, L, Bourenkov, G.P, Katchalova, G, Janssen, K.P, Bartunik, H.D, Noegel, A.A, Schleicher, M, Holak, T.A. | Deposit date: | 2004-01-01 | Release date: | 2004-01-27 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | STRUCTURE OF THE N-TERMINAL DOMAIN OF THE ADENYLYL
CYCLASE-ASSOCIATED PROTEIN (CAP) FROM DICTYOSTELIUM DISCOIDEUM Structure, 11, 2003
|
|
3FVT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fvt by Molmil](/molmil-images/mine/3fvt) | |
7TDQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7tdq by Molmil](/molmil-images/mine/7tdq) | |
1S28
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s28 by Molmil](/molmil-images/mine/1s28) | Crystal Structure of AvrPphF ORF1, the Chaperone for the Type III Effector AvrPphF ORF2 from P. syringae | Descriptor: | ORF1, SULFATE ION | Authors: | Singer, A.U, Desveaux, D, Betts, L, Chang, J.H, Nimchuk, Z, Grant, S.R, Dangl, J.L, Sondek, J. | Deposit date: | 2004-01-08 | Release date: | 2004-09-14 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal Structures of the Type III Effector Protein AvrPphF and Its Chaperone Reveal Residues Required for Plant Pathogenesis Structure, 12, 2004
|
|
3FYU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fyu by Molmil](/molmil-images/mine/3fyu) | |
1S0G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s0g by Molmil](/molmil-images/mine/1s0g) | |
6BY4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6by4 by Molmil](/molmil-images/mine/6by4) | Single-State 14-mer UUCG Tetraloop calculated from Exact NOEs | Descriptor: | RNA (5'-R(P*GP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*C)-3') | Authors: | Nichols, P.J, Henen, M.A, Born, A, Strotz, D, Guntert, P, Vogeli, B. | Deposit date: | 2017-12-19 | Release date: | 2018-06-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints. Commun Biol, 1, 2018
|
|
1S2W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s2w by Molmil](/molmil-images/mine/1s2w) | Crystal structure of phosphoenolpyruvate mutase in high ionic strength | Descriptor: | Phosphoenolpyruvate phosphomutase, SULFATE ION | Authors: | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | Deposit date: | 2004-01-11 | Release date: | 2004-05-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Conformational Flexibility of PEP Mutase Biochemistry, 43, 2004
|
|
6BY5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6by5 by Molmil](/molmil-images/mine/6by5) | Two-State 14-mer UUCG Tetraloop calculated from Exact NOEs (State one: Conformers 1-5, State Two: Conformers 6-10) | Descriptor: | RNA (5'-R(P*GP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*C)-3') | Authors: | Nichols, P.J, Henen, M.A, Born, A, Strotz, D, Guntert, P, Vogeli, B. | Deposit date: | 2017-12-19 | Release date: | 2018-06-13 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | High-resolution small RNA structures from exact nuclear Overhauser enhancement measurements without additional restraints. Commun Biol, 1, 2018
|
|
7UFZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ufz by Molmil](/molmil-images/mine/7ufz) | Crystal structure of TDP1 complexed with compound XZ768 | Descriptor: | (4-{[(4S)-2-phenylimidazo[1,2-a]pyridin-3-yl]amino}phenyl)phosphonic acid, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | Authors: | Lountos, G.T, Zhao, X.Z, Wang, W, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R. | Deposit date: | 2022-03-23 | Release date: | 2023-04-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.559 Å) | Cite: | Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1. Front Chem, 10, 2022
|
|
6BNH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bnh by Molmil](/molmil-images/mine/6bnh) | Solution NMR structures of BRD4 ET domain with JMJD6 peptide | Descriptor: | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Bromodomain-containing protein 4 | Authors: | Konuma, T, Yu, D, Zhao, C, Ju, Y, Sharma, R, Ren, C, Zhang, Q, Zhou, M.-M, Zeng, L. | Deposit date: | 2017-11-16 | Release date: | 2017-12-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural Mechanism of the Oxygenase JMJD6 Recognition by the Extraterminal (ET) Domain of BRD4. Sci Rep, 7, 2017
|
|
1S5Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s5z by Molmil](/molmil-images/mine/1s5z) | NDP kinase in complex with adenosine phosphonoacetic acid | Descriptor: | ADENOSINE PHOSPHONOACETIC ACID, Nucleoside diphosphate kinase, cytosolic, ... | Authors: | Chen, Y, Morera, S, Pasti, C, Angusti, A, Solaroli, N, Veron, M, Janin, J, Manfredini, S, Deville-Bonne, D. | Deposit date: | 2004-01-22 | Release date: | 2005-02-01 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Adenosine phosphonoacetic acid is slowly metabolized by NDP kinase. Med.Chem., 1, 2005
|
|
7UFY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ufy by Molmil](/molmil-images/mine/7ufy) | Crystal structure of TDP1 complexed with compound XZ766 | Descriptor: | 1,2-ETHANEDIOL, Tyrosyl-DNA phosphodiesterase 1, [(4-{[(4S)-2,7-diphenylimidazo[1,2-a]pyridin-3-yl]amino}phenyl)methyl]phosphonic acid | Authors: | Lountos, G.T, Zhao, X.Z, Wang, W, Tropea, J.E, Needle, D, Pommier, Y, Burke, T.R. | Deposit date: | 2022-03-23 | Release date: | 2023-04-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.584 Å) | Cite: | Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1. Front Chem, 10, 2022
|
|
1S96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1s96 by Molmil](/molmil-images/mine/1s96) | The 2.0 A X-ray structure of Guanylate Kinase from E.coli | Descriptor: | Guanylate kinase, PHOSPHATE ION, UNKNOWN ATOM OR ION | Authors: | Kreusch, A, Spraggon, G, Klock, H.E, McMullan, D, Vincent, J, Rodrigues, K, Lesley, S.A. | Deposit date: | 2004-02-03 | Release date: | 2004-02-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Structure of Guanylate Kinase from Escherichia coli at 2.0 A resolution To be Published
|
|