3C0B
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![BU of 3c0b by Molmil](/molmil-images/mine/3c0b) | Crystal structure of the conserved archaeal protein Q6M145. Northeast Structural Genomics Consortium target MrR63 | Descriptor: | CALCIUM ION, Conserved archaeal protein Q6M145 | Authors: | Kuzin, A.P, Su, M, Seetharaman, J, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-01-19 | Release date: | 2008-02-26 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | X-ray structure of the conserved archaeal protein Q6M145. To be Published
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8J7N
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3C8T
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![BU of 3c8t by Molmil](/molmil-images/mine/3c8t) | Crystal structure of fumarate lyase from Mesorhizobium sp. BNC1 | Descriptor: | Fumarate lyase | Authors: | Bonanno, J.B, Freeman, J, Bain, K.T, Chang, S, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-02-13 | Release date: | 2008-03-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of fumarate lyase from Mesorhizobium sp. BNC1. To be Published
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3C98
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![BU of 3c98 by Molmil](/molmil-images/mine/3c98) | Revised structure of the munc18a-syntaxin1 complex | Descriptor: | Syntaxin-1A, Syntaxin-binding protein 1 | Authors: | Hattendorf, D.A, Misura, K.M, Burkhardt, P, Scheller, R.H, Fasshauer, D, Weis, W.I. | Deposit date: | 2008-02-15 | Release date: | 2008-03-25 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide Embo J., 27, 2008
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3FTH
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8JBE
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![BU of 8jbe by Molmil](/molmil-images/mine/8jbe) | CryoEM Structure of metazoan Mon1-Ccz1-RMC1 complex | Descriptor: | Caffeine, calcium, zinc sensitivity 1, ... | Authors: | Jia, G.W, Yong, X, Su, Z.M, Jia, D. | Deposit date: | 2023-05-08 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | CryoEM Structure of metazoan Mon1-Ccz1-RMC1 complex To Be Published
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2VRN
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![BU of 2vrn by Molmil](/molmil-images/mine/2vrn) | The structure of the stress response protein DR1199 from Deinococcus radiodurans: a member of the DJ-1 superfamily | Descriptor: | MAGNESIUM ION, PROTEASE I | Authors: | Fioravanti, E, Dura, M.A, Lascoux, D, Micossi, E, McSweeney, S. | Deposit date: | 2008-04-09 | Release date: | 2008-10-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of the stress response protein DR1199 from Deinococcus radiodurans: a member of the DJ-1 superfamily. Biochemistry, 47, 2008
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3C8H
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![BU of 3c8h by Molmil](/molmil-images/mine/3c8h) | Crystal structure of the enterobactin esterase FES from Shigella flexneri in the presence of 2,3-Di-hydroxy-N-benzoyl-serine | Descriptor: | Enterochelin esterase | Authors: | Kim, Y, Maltseva, N, Abergel, R, Holzle, D, Raymond, K, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-02-12 | Release date: | 2008-02-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Siderophore Mediated Iron Acquisition: Structure and Specificity of Enterobactin Esterase from Shigella flexneri. To be Published
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4RW3
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![BU of 4rw3 by Molmil](/molmil-images/mine/4rw3) | Structural insights into substrate binding of brown spider venom class II phospholipases D | Descriptor: | D-MYO-INOSITOL-1-PHOSPHATE, DECANOIC ACID, DI(HYDROXYETHYL)ETHER, ... | Authors: | Coronado, M.A, Ullah, A, da Silva, L.S, Chaves-Moreira, D, Vuitika, L, Chaim, O.M, Veiga, S.S, Chahine, J, Murakami, M.T, Arni, R.K. | Deposit date: | 2014-12-01 | Release date: | 2015-06-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Structural Insights into Substrate Binding of Brown Spider Venom Class II Phospholipases D. Curr Protein Pept Sci, 16, 2015
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3CAE
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8J7P
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8JSX
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2VWX
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![BU of 2vwx by Molmil](/molmil-images/mine/2vwx) | ephB4 kinase domain inhibitor complex | Descriptor: | 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide, EPHRIN TYPE-B RECEPTOR 4, MAGNESIUM ION | Authors: | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Barratt, D, Leach, A.G, Kettle, J.G. | Deposit date: | 2008-06-27 | Release date: | 2008-10-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Inhibitors of the Tyrosine Kinase Ephb4. Part 2: Structure-Based Discovery and Optimisation of 3,5-Bis Substituted Anilinopyrimidines. Bioorg.Med.Chem.Lett., 18, 2008
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8JT5
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![BU of 8jt5 by Molmil](/molmil-images/mine/8jt5) | VMAT2 complex with histamine | Descriptor: | HISTAMINE, Synaptic vesicular amine transporter | Authors: | Jiang, D.H, Wu, D. | Deposit date: | 2023-06-21 | Release date: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.06 Å) | Cite: | VMAT2 complex with histamine To Be Published
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8J8G
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![BU of 8j8g by Molmil](/molmil-images/mine/8j8g) | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 in complex with a DNA duplex and cidofovir diphosphate | Descriptor: | CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(P*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*GP*AP*TP*AP*AP*CP*TP*TP*AP*AP*TP*CP*TP*CP*AP*CP*AP*TP*AP*GP*CP*AP*GP*CP*T)-3'), ... | Authors: | Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C. | Deposit date: | 2023-05-01 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.79 Å) | Cite: | Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir. Int.J.Biol.Macromol., 270, 2024
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2VWZ
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![BU of 2vwz by Molmil](/molmil-images/mine/2vwz) | ephB4 kinase domain inhibitor complex | Descriptor: | EPHRIN TYPE-B RECEPTOR 4, MAGNESIUM ION, N-[3-[[4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL]AMINO]PHENYL]METHANESULFONAMIDE | Authors: | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Barratt, D, Leach, A.G, Kettle, J.G. | Deposit date: | 2008-06-30 | Release date: | 2008-10-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Inhibitors of the Tyrosine Kinase Ephb4. Part 2: Structure-Based Discovery and Optimisation of 3,5-Bis Substituted Anilinopyrimidines. Bioorg.Med.Chem.Lett., 18, 2008
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2VX1
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![BU of 2vx1 by Molmil](/molmil-images/mine/2vx1) | ephB4 kinase domain inhibitor complex | Descriptor: | 3-({4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYRIMIDIN-2-YL}AMINO)BENZAMIDE, EPHRIN TYPE-B RECEPTOR 4, MAGNESIUM ION | Authors: | Read, J, Brassington, C.A, Green, I, McCall, E.J, Valentine, A.L, Barratt, D, Leach, A.G, Kettle, J.G. | Deposit date: | 2008-06-30 | Release date: | 2008-10-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Inhibitors of the Tyrosine Kinase Ephb4. Part 2: Structure-Based Discovery and Optimisation of 3,5-Bis Substituted Anilinopyrimidines. Bioorg.Med.Chem.Lett., 18, 2008
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8J8F
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![BU of 8j8f by Molmil](/molmil-images/mine/8j8f) | Monkeypox virus DNA replication holoenzyme F8, A22 and E4 in complex with a DNA duplex and dCTP | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*GP*CP*TP*GP*CP*TP*AP*TP*GP*AP*GP*AP*TP*TP*AP*AP*GP*TP*TP*AP*T)-3'), ... | Authors: | Xu, Y, Wu, Y, Wu, X, Zhang, Y, Yang, Y, Li, D, Yang, B, Gao, K, Zhang, Z, Dong, C. | Deposit date: | 2023-05-01 | Release date: | 2024-05-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structural basis of human mpox viral DNA replication inhibition by brincidofovir and cidofovir. Int.J.Biol.Macromol., 270, 2024
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2VWS
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![BU of 2vws by Molmil](/molmil-images/mine/2vws) | Crystal structure of YfaU, a metal ion dependent class II aldolase from Escherichia coli K12 | Descriptor: | GLYCEROL, PHOSPHATE ION, YFAU, ... | Authors: | Rea, D, Rakus, J.F, Gerlt, J.A, Fulop, V, Bugg, T.D.H, Roper, D.I. | Deposit date: | 2008-06-26 | Release date: | 2008-09-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Crystal Structure and Functional Assignment of Yfau, a Metal Ion Dependent Class II Aldolase from Escherichia Coli K12. Biochemistry, 47, 2008
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2ZM2
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![BU of 2zm2 by Molmil](/molmil-images/mine/2zm2) | Structure of 6-aminohexanoate-dimer hydrolase, A61V/A124V/R187S/F264C/G291R/G338A/D370Y mutant (Hyb-S4M94) | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-aminohexanoate-dimer hydrolase, GLYCEROL, ... | Authors: | Ohki, T, Shibata, N, Higuchi, Y, Kawashima, Y, Takeo, M, Kato, D, Nego, S. | Deposit date: | 2008-04-10 | Release date: | 2009-04-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Two alternative modes for optimizing nylon-6 byproduct hydrolytic activity from a carboxylesterase with a beta-lactamase fold: X-ray crystallographic analysis of directly evolved 6-aminohexanoate-dimer hydrolase. Protein Sci., 18, 2009
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2ZVO
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![BU of 2zvo by Molmil](/molmil-images/mine/2zvo) | NEMO CoZi domain in complex with diubiquitin in C2 space group | Descriptor: | NF-kappa-B essential modulator, UBC protein | Authors: | Rahighi, S, Ikeda, F, Kawasaki, M, Akutsu, M, Suzuki, N, Kato, R, Kensche, T, Uejima, T, Bloor, S, Komander, D, Randow, F, Wakatsuki, S, Dikic, I. | Deposit date: | 2008-11-12 | Release date: | 2009-03-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation Cell(Cambridge,Mass.), 136, 2009
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4TQF
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![BU of 4tqf by Molmil](/molmil-images/mine/4tqf) | Crystal Structure of the C-terminal domain of IFRS bound with 2-(5-bromothienyl)-L-Ala and ATP | Descriptor: | 1,2-ETHANEDIOL, 3-(5-bromothiophen-2-yl)-L-alanine, ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Nakamura, A, O'Donoghue, P, Soll, D. | Deposit date: | 2014-06-11 | Release date: | 2014-11-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.7143 Å) | Cite: | Polyspecific pyrrolysyl-tRNA synthetases from directed evolution. Proc.Natl.Acad.Sci.USA, 111, 2014
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8JQU
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![BU of 8jqu by Molmil](/molmil-images/mine/8jqu) | Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Pandey, D, Zohib, M, Pal, R.K, Biswal, B.K, Arora, A. | Deposit date: | 2023-06-14 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Crystal structure of GppNHp bound GTPase domain of Rab5a from Leishmania donovani To Be Published
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2ZM0
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![BU of 2zm0 by Molmil](/molmil-images/mine/2zm0) | Structure of 6-aminohexanoate-dimer hydrolase, G181D/H266N/D370Y mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-aminohexanoate-dimer hydrolase, GLYCEROL, ... | Authors: | Ohki, T, Shibata, N, Higuchi, Y, Kawashima, Y, Takeo, M, Kato, D, Nego, S. | Deposit date: | 2008-04-10 | Release date: | 2009-04-07 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a beta-lactamase fold. Febs J., 276, 2009
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3BKJ
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![BU of 3bkj by Molmil](/molmil-images/mine/3bkj) | Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16) | Descriptor: | Amyloid Beta Peptide, WO2 IgG2a Fab fragment Heavy Chain, WO2 IgG2a Fab fragment Light Chain Kappa | Authors: | Miles, L.A, Wun, K.S, Crespi, G.A, Fodero-Tavoletti, M, Galatis, D, Bageley, C.J, Beyreuther, K, Masters, C.L, Cappai, R, McKinstry, W.J, Barnham, K.J, Parker, M.W. | Deposit date: | 2007-12-06 | Release date: | 2008-04-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Amyloid-beta-anti-amyloid-beta complex structure reveals an extended conformation in the immunodominant B-cell epitope. J.Mol.Biol., 377, 2008
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