4M6Q
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![BU of 4m6q by Molmil](/molmil-images/mine/4m6q) | Identification of Amides Derived From 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic Acid as Potent Inhibitors of Human Nicotinamide Phosphoribosyltransferase (NAMPT) | 分子名称: | 1-(5-O-phosphono-beta-D-ribofuranosyl)-N-(4-{[3-(trifluoromethyl)phenyl]sulfonyl}benzyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, ... | 著者 | Giannetti, A.M, Zheng, X, Skelton, N, Wang, W, Bravo, B, Feng, Y, Gunzner-Toste, J, Ho, Y, Hua, R, Wang, C, Zhao, Q, Liederer, B.M, Liu, Y, O'Brien, T, Oeh, J, Sampath, D, Shen, Y, Wang, L, Wu, H, Xiao, Y, Yuen, P, Zak, M, Zhao, G, Dragovich, P.S. | 登録日 | 2013-08-10 | 公開日 | 2013-09-25 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.406 Å) | 主引用文献 | Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT). Bioorg.Med.Chem.Lett., 23, 2013
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4L78
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![BU of 4l78 by Molmil](/molmil-images/mine/4l78) | Xenon Trapping and Statistical Coupling Analysis Uncover Regions Important for Structure and Function of Multidomain Protein StPurL | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | 著者 | Tanwar, A.S, Goyal, V.D, Choudhary, D, Panjikar, S, Anand, R. | 登録日 | 2013-06-13 | 公開日 | 2013-12-11 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Importance of hydrophobic cavities in allosteric regulation of formylglycinamide synthetase: insight from xenon trapping and statistical coupling analysis Plos One, 8, 2013
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4LDY
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![BU of 4ldy by Molmil](/molmil-images/mine/4ldy) | Crystal structure of the DNA binding domain of the G245A mutant of arabidopsis thaliana auxin reponse factor 1 | 分子名称: | Auxin response factor 1, CHLORIDE ION | 著者 | Boer, D.R, Freire-Rios, A, van den Berg, W.M.A, Weijers, D, Coll, M. | 登録日 | 2013-06-25 | 公開日 | 2014-02-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural Basis for DNA Binding Specificity by the Auxin-Dependent ARF Transcription Factors. Cell(Cambridge,Mass.), 156, 2014
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4LKK
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![BU of 4lkk by Molmil](/molmil-images/mine/4lkk) | The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with human receptor analog 6'SLNLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose, hemagglutinin | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | 登録日 | 2013-07-07 | 公開日 | 2013-11-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.491 Å) | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4LKH
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![BU of 4lkh by Molmil](/molmil-images/mine/4lkh) | The structure of hemagglutinin from a avian-origin H7N9 influenza virus (A/Shanghai/1/2013) in complex with human receptor analog 6'SLNLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | 登録日 | 2013-07-07 | 公開日 | 2013-11-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.099 Å) | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4L4E
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![BU of 4l4e by Molmil](/molmil-images/mine/4l4e) | Structure of cyanide and camphor bound P450cam mutant L358A/K178G | 分子名称: | CAMPHOR, CYANIDE ION, Camphor 5-monooxygenase, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.261 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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4L6V
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![BU of 4l6v by Molmil](/molmil-images/mine/4l6v) | Crystal structure of a virus like photosystem I from the cyanobacterium Synechocystis PCC 6803 | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | 著者 | Mazor, Y, Nataf, D, Toporik, H, Nelson, N. | 登録日 | 2013-06-13 | 公開日 | 2014-02-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structures of virus-like photosystem I complexes from the mesophilic cyanobacterium Synechocystis PCC 6803. Elife, 3, 2014
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4LCX
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![BU of 4lcx by Molmil](/molmil-images/mine/4lcx) | The structure of hemagglutinin from avian-origin H7N9 influenza virus (A/Shanghai/1/2013) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2 | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | 登録日 | 2013-06-24 | 公開日 | 2013-11-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.094 Å) | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses. Science, 342, 2013
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7FU4
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![BU of 7fu4 by Molmil](/molmil-images/mine/7fu4) | Crystal Structure of human cyclic GMP-AMP synthase in complex with 2-[(2-fluoro-4-phenylphenyl)methylamino]-5-propyl-4H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one | 分子名称: | (8S)-2-{[(3-fluoro[1,1'-biphenyl]-4-yl)methyl]amino}-5-propyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, Cyclic GMP-AMP synthase, ZINC ION | 著者 | Leibrock, L, Benz, J, Groebke-Zbinden, K, Hunziker, D, Rudolph, M.G. | 登録日 | 2023-02-08 | 公開日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.926 Å) | 主引用文献 | Crystal Structure of a human cyclic GMP-AMP synthase complex To be published
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4LK5
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![BU of 4lk5 by Molmil](/molmil-images/mine/4lk5) | Crystal structure of a enoyl-CoA hydratase from Mycobacterium avium subsp. paratuberculosis K-10 | 分子名称: | enoyl-CoA hydratase | 著者 | Kumaran, D, Chamala, S, Evans, B, Foti, R, Gizzi, A, Hillerich, B, Kar, A, Lafleur, J, Seidel, R, Villigas, G, Zencheck, W, Al Obaidi, N, Almo, S.C, Swaminathan, S, New York Structural Genomics Research Consortium (NYSGRC) | 登録日 | 2013-07-06 | 公開日 | 2013-07-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a enoyl-CoA hydratase from Mycobacterium avium subsp. paratuberculosis K-10 To be Published
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4L99
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![BU of 4l99 by Molmil](/molmil-images/mine/4l99) | Structure of the RBP from lactococcal phage 1358 in complex with glycerol | 分子名称: | GLYCEROL, Receptor Binding Protein, ZINC ION | 著者 | Farenc, C, Spinelli, S, Bebeacua, C, Tremblay, D, Orlov, I, Blangy, S, Klaholz, B.P, Moineau, S, Cambillau, C. | 登録日 | 2013-06-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A Virulent Siphophage CyoEM Structure and Host Recognition and Infection Mechanism To be Published
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4LKJ
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![BU of 4lkj by Molmil](/molmil-images/mine/4lkj) | The structure of hemagglutinin L226Q mutant (H3 numbering) from a avian-origin H7N9 influenza virus (A/Anhui/1/2013) in complex with avian receptor analog 3'SLNLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | 著者 | Shi, Y, Zhang, W, Wang, F, Qi, J, Song, H, Wu, Y, Gao, F, Zhang, Y, Fan, Z, Gong, W, Wang, D, Shu, Y, Wang, Y, Yan, J, Gao, G.F. | 登録日 | 2013-07-07 | 公開日 | 2013-11-06 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | 主引用文献 | Structures and receptor binding of hemagglutinins from human-infecting H7N9 influenza viruses Science, 342, 2013
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4L97
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![BU of 4l97 by Molmil](/molmil-images/mine/4l97) | Structure of the RBP of lactococcal phage 1358 in complex with glucose-1-phosphate | 分子名称: | 1-O-phosphono-alpha-D-glucopyranose, Receptor Binding Protein | 著者 | Farenc, C, Spinelli, S, Bebeacua, C, Tremblay, D, Orlov, I, Blangy, S, Klaholz, B.P, Moineau, S, Cambillau, C. | 登録日 | 2013-06-18 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | A Virulent Siphophage CyoEM Structure and Host Recognition and Infection Mechanism To be Published
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4L4A
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![BU of 4l4a by Molmil](/molmil-images/mine/4l4a) | Structure of L358A/K178G mutant of P450cam bound to camphor | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Batabyal, D, Li, H, Poulos, T.L. | 登録日 | 2013-06-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.103 Å) | 主引用文献 | Synergistic Effects of Mutations in Cytochrome P450cam Designed To Mimic CYP101D1. Biochemistry, 52, 2013
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4KUO
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![BU of 4kuo by Molmil](/molmil-images/mine/4kuo) | A superfast recovering full-length LOV protein from the marine phototrophic bacterium Dinoroseobacter shibae (Photoexcited state) | 分子名称: | RIBOFLAVIN, blue-light photoreceptor | 著者 | Circolone, F, Granzin, J, Stadler, A, Krauss, U, Drepper, T, Endres, S, Knieps-Gruenhagen, E, Wirtz, A, Willbold, D, Batra-Safferling, R, Jaeger, K.-E. | 登録日 | 2013-05-22 | 公開日 | 2014-11-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and function of a short LOV protein from the marine phototrophic bacterium Dinoroseobacter shibae. BMC Microbiol, 15, 2015
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4L61
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![BU of 4l61 by Molmil](/molmil-images/mine/4l61) | |
4L8M
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![BU of 4l8m by Molmil](/molmil-images/mine/4l8m) | Human p38 MAP kinase in complex with a Dibenzoxepinone | 分子名称: | Mitogen-activated protein kinase 14, N-[2-fluoro-5-({9-[2-(morpholin-4-yl)ethoxy]-11-oxo-6,11-dihydrodibenzo[b,e]oxepin-3-yl}amino)phenyl]benzamide, octyl beta-D-glucopyranoside | 著者 | Richters, A, Mayer-Wrangowski, S.C, Gruetter, C, Rauh, D. | 登録日 | 2013-06-17 | 公開日 | 2013-10-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Metabolically Stable Dibenzo[b,e]oxepin-11(6H)-ones as Highly Selective p38 MAP Kinase Inhibitors: Optimizing Anti-Cytokine Activity in Human Whole Blood. J.Med.Chem., 56, 2013
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4KWS
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![BU of 4kws by Molmil](/molmil-images/mine/4kws) | Crystal structure of d-mannonate dehydratase from chromohalobacter salexigens complexed with Mg and glycerol | 分子名称: | CHLORIDE ION, D-mannonate dehydratase, GLYCEROL, ... | 著者 | Fedorov, A.A, Fedorov, E.V, Wichelecki, D, Gerlt, J.A, Almo, S.C. | 登録日 | 2013-05-24 | 公開日 | 2014-05-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.642 Å) | 主引用文献 | Crystal structure of d-mannonate dehydratase from chromohalobacter salexigens complexed with Mg and glycerol To be Published
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4L0C
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![BU of 4l0c by Molmil](/molmil-images/mine/4l0c) | Crystal structure of the N-Fopmylmaleamic acid deformylase Nfo(S94A) from Pseudomonas putida S16 | 分子名称: | ACETIC ACID, DI(HYDROXYETHYL)ETHER, Deformylase | 著者 | Chen, D, Lu, Y, Zhang, Z, Wu, G, Xu, P. | 登録日 | 2013-05-31 | 公開日 | 2014-06-04 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of the N-Fopmylmaleamic acid deformylase Nfo from Pseudomonas putida S16 To be Published
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4LED
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![BU of 4led by Molmil](/molmil-images/mine/4led) | The Crystal Structure of Pyocin L1 bound to D-rhamnose at 2.37 Angstroms | 分子名称: | Pyocin L1, alpha-D-rhamnopyranose | 著者 | Grinter, R, Roszak, A.W, Mccaughey, L, Cogdell, C.J, Walker, D. | 登録日 | 2013-06-25 | 公開日 | 2014-02-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Lectin-Like Bacteriocins from Pseudomonas spp. Utilise D-Rhamnose Containing Lipopolysaccharide as a Cellular Receptor. Plos Pathog., 10, 2014
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4L64
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![BU of 4l64 by Molmil](/molmil-images/mine/4l64) | Crystal structure of the Candida albicans Methionine Synthase in complex with 5-Methyl-Tetrahydrofolate | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, ZINC ION | 著者 | Ubhi, D, Robertus, J.D. | 登録日 | 2013-06-11 | 公開日 | 2014-03-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structural analysis of a fungal methionine synthase with substrates and inhibitors. J.Mol.Biol., 426, 2014
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4JYC
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![BU of 4jyc by Molmil](/molmil-images/mine/4jyc) | MeaB, A Bacterial Homolog of MMAA, in its Apo form | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Methylmalonyl-CoA mutase accessory protein | 著者 | Koutmos, M, Lofgren, M, Padovani, D, Banerjee, R. | 登録日 | 2013-03-29 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A switch III motif relays signaling between a B12 enzyme and its G-protein chaperone. Nat.Chem.Biol., 9, 2013
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4JYB
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![BU of 4jyb by Molmil](/molmil-images/mine/4jyb) | MeaB, A Bacterial Homolog of MMAA, Bound to GMPPNP | 分子名称: | Methylmalonyl-CoA mutase accessory protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | 著者 | Koutmos, M, Lofgren, M, Padovani, D, Banerjee, R. | 登録日 | 2013-03-29 | 公開日 | 2013-07-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A switch III motif relays signaling between a B12 enzyme and its G-protein chaperone. Nat.Chem.Biol., 9, 2013
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4JYO
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![BU of 4jyo by Molmil](/molmil-images/mine/4jyo) | Structural basis for angiopoietin-1 mediated signaling initiation | 分子名称: | Angiopoietin-1, CALCIUM ION | 著者 | Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A. | 登録日 | 2013-03-31 | 公開日 | 2013-05-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for angiopoietin-1-mediated signaling initiation. Proc.Natl.Acad.Sci.USA, 110, 2013
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4JZC
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![BU of 4jzc by Molmil](/molmil-images/mine/4jzc) | Angiopoietin-2 fibrinogen domain TAG mutant | 分子名称: | Angiopoietin-2 | 著者 | Yu, X, Seegar, T.C.M, Dalton, A.C, Tzvetkova-Robev, D, Goldgur, Y, Nikolov, D.B, Barton, W.A. | 登録日 | 2013-04-02 | 公開日 | 2013-05-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for angiopoietin-1-mediated signaling initiation. Proc.Natl.Acad.Sci.USA, 110, 2013
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