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PDB: 22297 件

3IYQ
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tmRNA-SmpB: a journey to the center of the bacterial ribosome
分子名称: SsrA-binding protein, tmRNA
著者Weis, F, Bron, P, Giudice, E, Rolland, J.P, Thomas, D, Felden, B, Gillet, R.
登録日2010-04-16
公開日2010-10-20
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献tmRNA-SmpB: a journey to the centre of the bacterial ribosome.
Embo J., 29, 2010
3IV1
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BU of 3iv1 by Molmil
Coiled-coil domain of tumor susceptibility gene 101
分子名称: CHLORIDE ION, SULFATE ION, Tumor susceptibility gene 101 protein
著者Neculai, D, Avvakumov, G.V, Wernimont, A.K, Xue, S, Walker, J.R, Li, Y, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2009-08-31
公開日2009-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Coiled-Coil Domain of Human Tsg101
To be Published
6FM3
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BU of 6fm3 by Molmil
Deoxyguanylosuccinate synthase (DgsS) structure with ADP at 1.9 Angstrom resolution
分子名称: ADENOSINE-5'-DIPHOSPHATE, Adenylosuccinate synthetase, CHLORIDE ION
著者Sleiman, D, Loc'h, J, Haouz, A, Kaminski, P.A.
登録日2018-01-30
公開日2019-06-12
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Deoxyguanylosuccinate synthase (DgsS) quaternary structure with ATP0, dGMP, Magnesium at 2.3 Angstrom resolution
To Be Published
6TM5
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Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Nek2A substrate at 3.9 angstrom resolution
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Alfieri, C, Barford, D.
登録日2019-12-03
公開日2020-02-19
最終更新日2020-06-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献A unique binding mode of Nek2A to the APC/C allows its ubiquitination during prometaphase.
Embo Rep., 21, 2020
6FZO
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BU of 6fzo by Molmil
SMURFP-Y56F mutant
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ...
著者Janowski, R, Fuenzalida-Wernera, J.P, Mishra, K, Vetschera, P, Weidenfeld, I, Richter, K, Niessing, D, Ntziachristos, V, Stiel, A.C.
登録日2018-03-15
公開日2018-10-17
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a biliverdin-bound phycobiliprotein: Interdependence of oligomerization and chromophorylation.
J. Struct. Biol., 204, 2018
6FOX
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BU of 6fox by Molmil
The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with kynurenine
分子名称: (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, CALCIUM ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Levy, C.W, Leys, D.
登録日2018-02-08
公開日2019-08-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.
Commun Biol, 2, 2019
3IYS
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BU of 3iys by Molmil
Homology model of avian polyomavirus asymmetric unit
分子名称: Major capsid protein VP1
著者Shen, P.S, Enderlein, D, Nelson, C.D.S, Carter, W.S, Kawano, M, Xing, L, Swenson, R.D, Olson, N.H, Baker, T.S, Cheng, R.H, Atwood, W.J, Johne, R, Belnap, D.M.
登録日2010-04-19
公開日2011-01-26
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (11.3 Å)
主引用文献The structure of avian polyomavirus reveals variably sized capsids, non-conserved inter-capsomere interactions, and a possible location of the minor capsid protein VP4.
Virology, 411, 2011
6FPB
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BU of 6fpb by Molmil
Crystal structure of anti-mTFP1 DARPin 1238_G01 in space group I4
分子名称: CHLORIDE ION, DARPin 1238_G01
著者Jakob, R.P, Vigano, M.A, Bieli, D, Matsuda, S, Schaefer, J.V, Pluckthun, A, Affolter, M, Maier, T.
登録日2018-02-09
公開日2018-10-03
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.617 Å)
主引用文献DARPins recognizing mTFP1 as novel reagents forin vitroandin vivoprotein manipulations.
Biol Open, 7, 2018
6RW3
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BU of 6rw3 by Molmil
The molecular basis for sugar import in malaria parasites.
分子名称: Hexose transporter 1, alpha-D-glucopyranose, beta-D-glucopyranose
著者Qureshi, A, Matsuoka, R, Brock, J, Drew, D.
登録日2019-06-03
公開日2020-01-29
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献The molecular basis for sugar import in malaria parasites.
Nature, 578, 2020
3J02
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BU of 3j02 by Molmil
Lidless D386A Mm-cpn in the pre-hydrolysis ATP-bound state
分子名称: Lidless D386A Mm-cpn variant
著者Zhang, J, Ma, B, DiMaio, F, Douglas, N.R, Joachimiak, L, Baker, D, Frydman, J, Levitt, M, Chiu, W.
登録日2011-02-10
公開日2011-05-18
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure.
Structure, 19, 2011
6FQH
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GluA2(flop) S729C ligand binding core dimer bound to NBQX at 1.76 Angstrom resolution
分子名称: 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, Glutamate receptor 2,Glutamate receptor 2
著者Coombs, I.D, Soto, D, Gold, M.G, Farrant, M.F, Cull-Candy, S.G.
登録日2018-02-14
公開日2019-03-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.75940013 Å)
主引用文献Homomeric GluA2(R) AMPA receptors can conduct when desensitized.
Nat Commun, 10, 2019
6FS0
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BU of 6fs0 by Molmil
INDUCED MYELOID LEUKEMIA CELL DIFFERENTIATION PROTEIN FABCOMPLEX IN COMPLEX WITH AZD5991
分子名称: AZD5991, Fab Heavy Chain, Fab Light Chain, ...
著者Hargreaves, D.
登録日2018-02-18
公開日2018-12-26
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia.
Nat Commun, 9, 2018
6FSA
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BU of 6fsa by Molmil
Beta-Cardiac myosin post-rigor
分子名称: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, ...
著者Robert-Paganin, J, Auguin, D, Houdusse, A.
登録日2018-02-19
公開日2018-07-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Hypertrophic cardiomyopathy disease results from disparate impairments of cardiac myosin function and auto-inhibition.
Nat Commun, 9, 2018
3IXV
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BU of 3ixv by Molmil
Scorpion Hemocyanin resting state pseudo atomic model built based on cryo-EM density map
分子名称: Hemocyanin AA6 chain
著者Cong, Y, Zhang, Q, Woolford, D, Schweikardt, T, Khant, H, Ludtke, S, Chiu, W, Decker, H.
登録日2009-02-13
公開日2009-06-02
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献Structural Mechanism of SDS-Induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryomicroscopy.
Structure, 17, 2009
6RH5
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BU of 6rh5 by Molmil
Solution structure and 1H, 13C and 15N chemical shift assignments for NECAP1 PHear domain
分子名称: Adaptin ear-binding coat-associated protein 1
著者Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T.
登録日2019-04-18
公開日2019-09-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
3IW1
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BU of 3iw1 by Molmil
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP125 in complex with androstenedione
分子名称: 4-ANDROSTENE-3-17-DIONE, Cytochrome P450 CYP125, PROTOPORPHYRIN IX CONTAINING FE
著者McLean, K.J, Levy, C, Munro, A.W, Leys, D.
登録日2009-09-02
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.
J.Biol.Chem., 284, 2009
3IWK
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BU of 3iwk by Molmil
Crystal structure of aminoaldehyde dehydrogenase 1 from Pisum sativum (PsAMADH1)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, Aminoaldehyde dehydrogenase, GLYCEROL, ...
著者Kopecny, D, Morera, S, Briozzo, P.
登録日2009-09-02
公開日2010-01-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and functional characterization of plant aminoaldehyde dehydrogenase from Pisum sativum with a broad specificity for natural and synthetic aminoaldehydes.
J.Mol.Biol., 396, 2010
3IXW
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BU of 3ixw by Molmil
Scorpion Hemocyanin activated state pseudo atomic model built based on cryo-EM density map
分子名称: Hemocyanin AA6 chain
著者Cong, Y, Zhang, Q, Woolford, D, Schweikardt, T, Khant, H, Ludtke, S, Chiu, W, Decker, H.
登録日2009-02-13
公開日2009-06-02
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structural Mechanism of SDS-Induced Enzyme Activity of Scorpion Hemocyanin Revealed by Electron Cryomicroscopy.
Structure, 17, 2009
6FNH
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BU of 6fnh by Molmil
Crystal Structure of Ephrin A2 (EphA2) Receptor Protein Kinase with a pyrazolo[3,4-d]pyrimidine fragment of NVP-BHG712
分子名称: 1,2-ETHANEDIOL, 1-methyl-6-pyridin-3-yl-pyrazolo[3,4-d]pyrimidin-4-amine, Ephrin type-A receptor 2
著者Kudlinzki, D, Troester, A, Witt, K, Linhard, V.L, Gande, S.L, Saxena, K, Schwalbe, H.
登録日2018-02-04
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.379 Å)
主引用文献NVP-BHG712: Effects of Regioisomers on the Affinity and Selectivity toward the EPHrin Family.
ChemMedChem, 13, 2018
6FNW
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Structure of a volume-regulated anion channel of the LRRC8 family
分子名称: 1,2-ETHANEDIOL, Volume-regulated anion channel subunit LRRC8A
著者Deneka, D, Sawicka, M, Lam, A.K.M, Paulino, C, Dutzler, R.
登録日2018-02-05
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a volume-regulated anion channel of the LRRC8 family.
Nature, 558, 2018
6FOZ
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The crystal structure of P.fluorescens Kynurenine 3-monooxygenase (KMO) in complex with competitive inhibitor No. 13
分子名称: 5-(3,4-dichlorophenyl)furan-2-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, Kynurenine 3-monooxygenase
著者Levy, C.W, Leys, D.
登録日2018-02-08
公開日2019-08-21
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.
Commun Biol, 2, 2019
6FQB
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MurT/GatD peptidoglycan amidotransferase complex from Streptococcus pneumoniae R6
分子名称: Cobyric acid synthase, GLUTAMINE, Mur ligase family protein
著者Morlot, C, Contreras-Martel, C, Leisico, F, Straume, D, Peters, K, Hegnar, O.A, Simon, N, Villard, A.M, Breukink, E, Gravier-Pelletier, C, Le Corre, L, Vollmer, W, Pietrancosta, N, Havarstein, L.S, Zapun, A.
登録日2018-02-13
公開日2018-08-22
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the essential peptidoglycan amidotransferase MurT/GatD complex from Streptococcus pneumoniae.
Nat Commun, 9, 2018
6RKC
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BU of 6rkc by Molmil
Inter-dimeric interface controls function and stability of S-methionine adenosyltransferase from U. urealiticum
分子名称: (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, Methionine adenosyltransferase, ...
著者Shahar, A, Zarivach, R, Bershtein, S, Kleiner, D, Shmulevich, F.
登録日2019-04-30
公開日2019-09-25
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献The interdimeric interface controls function and stability of Ureaplasma urealiticum methionine S-adenosyltransferase.
J.Mol.Biol., 431, 2019
3L8P
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Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207
分子名称: 2-methyl-11-(1-methylethyl)-8-[(2S)-tetrahydro-2H-pyran-2-yl]-2,11,12,13-tetrahydro-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, Angiopoietin-1 receptor
著者Fedorov, A.A, Fedorov, E.V, Pauletti, D, Meyer, S.L, Hudkins, R.L, Almo, S.C.
登録日2010-01-03
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207
To be Published
3L8Y
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Complex of Ras with cyclen
分子名称: 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ...
著者Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R.
登録日2010-01-04
公開日2011-01-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes
Angew.Chem.Int.Ed.Engl., 49, 2010

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