2VRH
| Structure of the E. coli trigger factor bound to a translating ribosome | 分子名称: | 50S RIBOSOMAL PROTEIN L23, 50S RIBOSOMAL PROTEIN L24, 50S RIBOSOMAL PROTEIN L29, ... | 著者 | Merz, F, Boehringer, D, Schaffitzel, C, Preissler, S, Hoffmann, A, Maier, T, Rutkowska, A, Lozza, J, Ban, N, Bukau, B, Deuerling, E. | 登録日 | 2008-04-07 | 公開日 | 2008-06-17 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (19 Å) | 主引用文献 | Molecular Mechanism and Structure of Trigger Factor Bound to the Translating Ribosome. Embo J., 27, 2008
|
|
1QGH
| THE X-RAY STRUCTURE OF THE UNUSUAL DODECAMERIC FERRITIN FROM LISTERIA INNOCUA, REVEALS A NOVEL INTERSUBUNIT IRON BINDING SITE. | 分子名称: | FE (III) ION, NON-HEME IRON-CONTAINING FERRITIN | 著者 | Ilari, A, Stefanini, S, Chiancone, E, Tsernoglou, D. | 登録日 | 1999-04-27 | 公開日 | 2000-01-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The dodecameric ferritin from Listeria innocua contains a novel intersubunit iron-binding site. Nat.Struct.Biol., 7, 2000
|
|
4FGM
| Crystal structure of the aminopeptidase N family protein Q5QTY1 from Idiomarina loihiensis. Northeast Structural Genomics Consortium Target IlR60. | 分子名称: | Aminopeptidase N family protein, MALEIC ACID, ZINC ION | 著者 | Vorobiev, S, Su, M, Tong, T, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-06-04 | 公開日 | 2012-08-01 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.394 Å) | 主引用文献 | Crystal structure of the aminopeptidase N family protein Q5QTY1 from Idiomarina loihiensis. To be Published
|
|
1QO1
| Molecular Architecture of the Rotary Motor in ATP Synthase from Yeast Mitochondria | 分子名称: | ATP SYNTHASE ALPHA CHAIN, ATP SYNTHASE BETA CHAIN, ATP SYNTHASE DELTA CHAIN, ... | 著者 | Stock, D, Leslie, A.G.W, Walker, J.E. | 登録日 | 1999-11-01 | 公開日 | 1999-11-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | Molecular Architecture of the Rotary Motor in ATP Synthase Science, 286, 1999
|
|
2XP9
| DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | 分子名称: | 4-[BENZYL(CARBOXYMETHYL)CARBAMOYL]-2-PHENYL-1H-IMIDAZOLE-5-CARBOXYLIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | 著者 | Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D. | 登録日 | 2010-08-25 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution. Bioorg.Med.Chem.Lett., 20, 2010
|
|
1QKD
| |
2XP3
| DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | 分子名称: | 5-(2-METHOXYPHENYL)-2-FUROIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | 著者 | Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D. | 登録日 | 2010-08-25 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution. Bioorg.Med.Chem.Lett., 20, 2010
|
|
1QO2
| Crystal structure of N-((5'-phosphoribosyl)-formimino)-5-aminoimidazol-4-carboxamid ribonucleotid isomerase (EC 3.1.3.15, HisA) | 分子名称: | | 著者 | Wilmanns, M, Lang, D, Thoma, R, Sterner, R. | 登録日 | 1999-11-01 | 公開日 | 2000-07-12 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Evidence for Evolution of the Beta/Alpha-Barrel Scaffold by Repeated Gene Duplication and Fusion Science, 289, 2000
|
|
2XPC
| Second-generation sulfonamide inhibitors of MurD: Activity optimisation with conformationally rigid analogues of D-glutamic acid | 分子名称: | (1R,3R,4S)-4-[({6-[(4-CYANO-2-FLUOROBENZYL)OXY]NAPHTHALEN-2-YL}SULFONYL)AMINO]CYCLOHEXANE-1,3-DICARBOXYLIC ACID, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | 著者 | Sosic, I, Barreteau, H, Simcic, M, Sink, R, Cesar, J, Golic-Grdadolnik, S, Contreras-Martel, C, Dessen, A, Amoroso, A, Joris, B, Blanot, D, Gobec, S. | 登録日 | 2010-08-26 | 公開日 | 2011-05-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | Second-Generation Sulfonamide Inhibitors of D- Glutamic Acid-Adding Enzyme: Activity Optimisation with Conformationally Rigid Analogues of D- Glutamic Acid. Eur.J.Med.Chem, 46, 2011
|
|
1QQQ
| CRYSTAL STRUCTURE ANALYSIS OF SER254 MUTANT OF ESCHERICHIA COLI THYMIDYLATE SYNTHASE | 分子名称: | SULFATE ION, THYMIDYLATE SYNTHASE | 著者 | Fantz, C, Shaw, D, Jennings, W, Forsthoefel, A, Kitchens, M, Phan, J, Minor, W, Lebioda, L, Berger, F.G, Spencer, H.T. | 登録日 | 1999-06-07 | 公開日 | 1999-06-14 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Drug-resistant variants of Escherichia coli thymidylate synthase: effects of substitutions at Pro-254. Mol.Pharmacol., 57, 2000
|
|
2XQQ
| Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide (Ac-SRGTQTE). | 分子名称: | ACETATE ION, DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, ... | 著者 | Rapali, P, Radnai, L, Suveges, D, Hetenyi, C, Harmat, V, Tolgyesi, F, Wahlgren, W.Y, Katona, G, Nyitray, L, Pal, G. | 登録日 | 2010-09-07 | 公開日 | 2011-05-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | 主引用文献 | Directed Evolution Reveals the Binding Motif Preference of the Lc8/Dynll Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome Plos One, 6, 2011
|
|
2XHE
| Crystal structure of the Unc18-syntaxin 1 complex from Monosiga brevicollis | 分子名称: | SYNTAXIN1, UNC18 | 著者 | Burkhardt, P, Stegmann, C.M, Wahl, M.C, Fasshauer, D. | 登録日 | 2010-06-14 | 公開日 | 2011-06-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Primordial Neurosecretory Apparatus Identified in the Choanoflagellate Monosiga Brevicollis. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
1QHA
| HUMAN HEXOKINASE TYPE I COMPLEXED WITH ATP ANALOGUE AMP-PNP | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Rosano, C, Sabini, E, Deriu, D, Magnani, M, Bolognesi, M. | 登録日 | 1999-05-11 | 公開日 | 1999-11-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Binding of non-catalytic ATP to human hexokinase I highlights the structural components for enzyme-membrane association control. Structure Fold.Des., 7, 1999
|
|
2XWA
| Crystal Structure of Complement Factor D Mutant R202A | 分子名称: | COMPLEMENT FACTOR D, GLYCEROL | 著者 | Forneris, F, Ricklin, D, Wu, J, Tzekou, A, Wallace, R.S, Lambris, J.D, Gros, P. | 登録日 | 2010-11-01 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation. Science, 330, 2010
|
|
1QOL
| STRUCTURE OF THE FMDV LEADER PROTEASE | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PROTEASE (NONSTRUCTURAL PROTEIN P20A) | 著者 | Guarne, A, Tormo, J, Kirchweger, R, Pfistermueller, D, Skern, T, Fita, I. | 登録日 | 1999-11-13 | 公開日 | 2000-11-10 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of the Foot-and-Mouth Disease Virus Leader Protease: A Papain-Like Fold Adapted for Self-Processing and Eif4G Recognition. Embo J., 17, 1998
|
|
2XJY
| Crystal structure of the LMO2:LDB1-LID complex, P21 crystal form | 分子名称: | LIM DOMAIN-BINDING PROTEIN 1, RHOMBOTIN-2, ZINC ION | 著者 | El Omari, K, Karia, D, Porcher, C, Mancini, E.J. | 登録日 | 2010-07-06 | 公開日 | 2010-07-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the Leukemia Oncogene Lmo2: Implications for the Assembly of a Hematopoietic Transcription Factor Complex. Blood, 117, 2011
|
|
1QPI
| CRYSTAL STRUCTURE OF TETRACYCLINE REPRESSOR/OPERATOR COMPLEX | 分子名称: | DNA (5'-D(*CP*CP*TP*AP*TP*CP*AP*AP*TP*GP*AP*TP*AP*GP*A)-3'), DNA (5'-D(*TP*CP*TP*AP*TP*CP*AP*TP*TP*GP*AP*TP*AP*GP*G)-3'), IMIDAZOLE, ... | 著者 | Orth, P, Schnappinger, D, Hillen, W, Saenger, W, Hinrichs, W. | 登録日 | 1999-05-25 | 公開日 | 2000-02-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis of gene regulation by the tetracycline inducible Tet repressor-operator system. Nat.Struct.Biol., 7, 2000
|
|
2Y0C
| BceC mutation Y10S | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GLYCEROL, ... | 著者 | Rocha, J, Popescu, A.O, Borges, P, Mil-Homens, D, Sa-Correia, I, Fialho, A.M, Frazao, C. | 登録日 | 2010-12-02 | 公開日 | 2011-07-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structure of Burkholderia Cepacia Udp-Glucose Dehydrogenase (Ugd) Bcec and Role of Tyr10 in Final Hydrolysis of Ugd Thioester Intermediate. J.Bacteriol., 193, 2011
|
|
1Q6T
| THE STRUCTURE OF PHOSPHOTYROSINE PHOSPHATASE 1B IN COMPLEX WITH COMPOUND 11 | 分子名称: | 6-[4-((2S)-2-(1H-1,2,3-BENZOTRIAZOL-1-YL)-3-{4-[DIFLUORO(PHOSPHONO)METHYL]PHENYL}-2-PHENYLPROPYL)PHENYL]-2-[(1S)-1-METHOXY-3-METHYLBUTYL]QUINOLIN-8-YLPHOSPHONIC ACID, MAGNESIUM ION, Protein-tyrosine phosphatase, ... | 著者 | Scapin, G, Patel, S.B, Becker, J.W, Wang, Q, Desponts, C, Waddleton, D, Skorey, K, Cromlish, W, Bayly, C, Therien, M, Gauthier, J.Y, Li, C.S, Lau, C.K, Ramachandran, C, Kennedy, B.P, Asante-Appiah, E. | 登録日 | 2003-08-13 | 公開日 | 2003-09-30 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The Structural Basis for the Selectivity of Benzotriazole Inhibitors of Ptp1B Biochemistry, 42, 2003
|
|
2XPU
| TetR(D) in complex with anhydrotetracycline. | 分子名称: | 5A,6-ANHYDROTETRACYCLINE, CHLORIDE ION, SULFATE ION, ... | 著者 | Dalm, D, Palm, G.J, Hinrichs, W. | 登録日 | 2010-08-30 | 公開日 | 2011-09-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Tetracycline Repressor Allostery Does not Depend on Divalent Metal Recognition. Biochemistry, 53, 2014
|
|
1PTX
| |
1PVH
| Crystal structure of leukemia inhibitory factor in complex with gp130 | 分子名称: | IODIDE ION, Interleukin-6 receptor beta chain, Leukemia inhibitory factor | 著者 | Boulanger, M.J, Bankovich, A.J, Kortemme, T, Baker, D, Garcia, K.C. | 登録日 | 2003-06-27 | 公開日 | 2003-10-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130. Mol.Cell, 12, 2003
|
|
2XP5
| DISCOVERY OF CELL-ACTIVE PHENYL-IMIDAZOLE PIN1 INHIBITORS BY STRUCTURE-GUIDED FRAGMENT EVOLUTION | 分子名称: | 5-METHYL-2-PHENYL-1H-IMIDAZOLE-4-CARBOXYLIC ACID, DODECAETHYLENE GLYCOL, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1 | 著者 | Potter, A, Oldfield, V, Nunns, C, Fromont, C, Ray, S, Northfield, C.J, Bryant, C.J, Scrace, S.F, Robinson, D, Matossova, N, Baker, L, Dokurno, P, Surgenor, A.E, Davis, B.E, Richardson, C.M, Murray, J.B, Moore, J.D. | 登録日 | 2010-08-25 | 公開日 | 2011-01-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of Cell-Active Phenyl-Imidazole Pin1 Inhibitors by Structure-Guided Fragment Evolution. Bioorg.Med.Chem.Lett., 20, 2010
|
|
1PPQ
| NMR structure of 16th module of Immune Adherence Receptor, Cr1 (Cd35) | 分子名称: | Complement receptor type 1 | 著者 | O'Leary, J.M, Bromek, K, Black, G.M, Uhrinova, S, Schmitz, C, Krych, M, Atkinson, J.P, Uhrin, D, Barlow, P.N. | 登録日 | 2003-06-17 | 公開日 | 2004-05-04 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces. Protein Sci., 13, 2004
|
|
2XYS
| Crystal structure of Aplysia californica AChBP in complex with strychnine | 分子名称: | SOLUBLE ACETYLCHOLINE RECEPTOR, STRYCHNINE | 著者 | Brams, M, Pandya, A, Kuzmin, D, van Elk, R, Krijnen, L, Yakel, J.L, Tsetlin, V, Smit, A.B, Ulens, C. | 登録日 | 2010-11-19 | 公開日 | 2011-03-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.909 Å) | 主引用文献 | A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and D-Tubocurarine by Different Cys-Loop Receptors. Plos Biol., 9, 2011
|
|