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PDB: 22202 件

1NJ5
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Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus bound to proline sulfamoyl adenylate
分子名称: '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, MAGNESIUM ION, Proline-tRNA Synthetase, ...
著者Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A.
登録日2002-12-30
公開日2003-03-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
7MZ6
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Cryo-EM structure of minimal TRPV1 with 1 perturbed PI
分子名称: (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ...
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZB
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Cryo-EM structure of minimal TRPV1 with 3 bound RTX and 1 perturbed PI
分子名称: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.72 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZC
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Cryo-EM structure of minimal TRPV1 with RTX bound in C1 state
分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
2RO2
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BU of 2ro2 by Molmil
Solution structure of domain I of the negative polarity CChMVd hammerhead ribozyme
分子名称: RNA (5'-R(*GP*GP*GP*AP*GP*AP*CP*CP*UP*GP*AP*AP*GP*UP*GP*GP*GP*UP*UP*UP*CP*CP*C)-3')
著者Gallego, J, Dufour, D, Gago, S, de la Pena, M, Flores, R.
登録日2008-03-05
公開日2008-12-30
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure-function analysis of the ribozymes of chrysanthemum chlorotic mottle viroid: a loop-loop interaction motif conserved in most natural hammerheads
Nucleic Acids Res., 37, 2009
7MZA
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BU of 7mza by Molmil
Cryo-EM structure of minimal TRPV1 with 2 bound RTX in adjacent pockets
分子名称: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZ9
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BU of 7mz9 by Molmil
Cryo-EM structure of minimal TRPV1 with 1 partially bound RTX
分子名称: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZ7
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BU of 7mz7 by Molmil
Cryo-EM structure of minimal TRPV1 with 4 partially bound RTX
分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7MZD
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BU of 7mzd by Molmil
Cryo-EM structure of minimal TRPV1 with RTX bound in C2 state
分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 1, resiniferatoxin
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
2RV8
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BU of 2rv8 by Molmil
Solution Structure of the PhoP DNA-Binding Domain from Mycobacterium tuberculosis
分子名称: DNA-binding response regulator
著者Macdonald, R, Sarkar, D, Amer, B.R, Clubb, R.T.
登録日2015-04-17
公開日2015-08-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the PhoP DNA-binding domain from Mycobacterium tuberculosis.
J.Biomol.Nmr, 63, 2015
7MZE
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BU of 7mze by Molmil
Cryo-EM structure of minimal TRPV1 with 2 bound RTX in opposite pockets
分子名称: (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ...
著者Zhang, K, Julius, D, Cheng, Y.
登録日2021-05-24
公開日2021-09-22
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.42 Å)
主引用文献Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
7NKZ
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BU of 7nkz by Molmil
Cryo-EM structure of the cytochrome bd oxidase from M. tuberculosis at 2.5 A resolution
分子名称: CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, HEME B/C, MENAQUINONE-9, ...
著者Safarian, S, Wu, D, Krause, K.L, Michel, H.
登録日2021-02-19
公開日2021-09-22
最終更新日2021-09-29
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB.
Nat Commun, 12, 2021
1NE2
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BU of 1ne2 by Molmil
Crystal Structure of Thermoplasma acidophilum 1320 (APC5513)
分子名称: FORMIC ACID, hypothetical protein ta1320
著者Kim, Y, Joachimiak, A, Edwards, A, Xu, X, Christendat, D, Midwest Center for Structural Genomics (MCSG)
登録日2002-12-10
公開日2003-07-01
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of Thermoplasma acidophilum 1320 (APC5513)
To be Published
7ZGV
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BU of 7zgv by Molmil
Serratia NucC bound to cA3
分子名称: ACETATE ION, CALCIUM ION, RNA (5'-R(P*AP*AP*A)-3'), ...
著者Garcia-Doval, C, Mayo-Munoz, D, Smith, L.M, Fineran, P.C.
登録日2022-04-04
公開日2022-10-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection.
Mol.Cell, 82, 2022
7ZGW
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BU of 7zgw by Molmil
Serratia NucC apo form
分子名称: Serratia NucC
著者Garcia-Doval, C, Mayo-Munoz, D, Smith, L.M, Fineran, P.C.
登録日2022-04-04
公開日2022-10-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Type III CRISPR-Cas provides resistance against nucleus-forming jumbo phages via abortive infection.
Mol.Cell, 82, 2022
2RMB
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BU of 2rmb by Molmil
Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A
分子名称: CYCLOSPORIN A, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE
著者Ke, H, Mayrose, D.
登録日1994-01-07
公開日1995-02-07
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structures of Cyclophilin a Complexed with Cyclosporin a and N-Methyl-4-[(E)-2-Butenyl]-4,4-Dimethylthreonine Cyclosporin A.
Structure, 2, 1994
1NIX
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BU of 1nix by Molmil
THREE DIMENSIONAL SOLUTION STRUCTURE OF HAINANTOXIN-I BY 2D 1H-NMR
分子名称: HAINANTOXIN-I
著者Li, D, Liang, S.
登録日2002-12-29
公開日2003-01-14
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana.
Febs Lett., 555, 2003
8A5Q
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BU of 8a5q by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on straight DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ...
著者Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
登録日2022-06-15
公開日2022-12-14
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
1NJ8
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Crystal Structure of Prolyl-tRNA Synthetase from Methanocaldococcus janaschii
分子名称: Proline-tRNA Synthetase
著者Kamtekar, S, Kennedy, W.D, Wang, J, Stathopoulos, C, Soll, D, Steitz, T.A.
登録日2002-12-30
公開日2003-03-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The structural basis of cysteine aminoacylation of tRNAPro by prolyl-tRNA synthetases
Proc.Natl.Acad.Sci.USA, 100, 2003
7NHG
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BU of 7nhg by Molmil
Crystal structure of the human METTL3-METTL14 complex with compound ASI_M3M_041
分子名称: ACETATE ION, N-[[(3R)-3-Hydroxy-1-[6-(methylamino)pyrimidin-4-yl]piperidin-3-yl]methyl]-4-(piperidin-1-ylmethyl)benzamide, N6-adenosine-methyltransferase catalytic subunit, ...
著者Bedi, R.K, Huang, D, Caflisch, A.
登録日2021-02-10
公開日2021-10-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
Acs Bio Med Chem Au, 2023
8A5P
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BU of 8a5p by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of Chaetomium thermophilum INO80 on curved DNA
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin related protein 4 (Arp4), ...
著者Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
登録日2022-06-15
公開日2022-12-14
最終更新日2022-12-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
8A5A
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BU of 8a5a by Molmil
Structure of Arp4-Ies4-N-actin-Arp8-Ino80HSA subcomplex (A-module) of INO80
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-like protein ARP8, ...
著者Kunert, F, Metzner, F.J, Eustermann, S, Jung, J, Woike, S, Schall, K, Kostrewa, D, Hopfner, K.P.
登録日2022-06-14
公開日2022-12-14
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural mechanism of extranucleosomal DNA readout by the INO80 complex.
Sci Adv, 8, 2022
7NIA
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BU of 7nia by Molmil
Crystal structure of the human METTL3-METTL14 complex with compound UOZ059a
分子名称: 4-[[(3R)-3-cyclopropyl-2-azaspiro[3.3]heptan-2-yl]methyl]-N-[[(3R)-3-oxidanyl-1-[6-[(phenylmethyl)amino]pyrimidin-4-yl]piperidin-3-yl]methyl]benzamide, ACETATE ION, N6-adenosine-methyltransferase catalytic subunit, ...
著者Bedi, R.K, Huang, D, Caflisch, A.
登録日2021-02-11
公開日2021-10-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
Acs Bio Med Chem Au, 2023
4HN4
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Tryptophan synthase in complex with alpha aminoacrylate E(A-A) form and the F9 inhibitor in the alpha site
分子名称: 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, BICINE, ...
著者Hilario, E, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L.
登録日2012-10-18
公開日2013-12-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Allostery and substrate channeling in the tryptophan synthase bienzyme complex: evidence for two subunit conformations and four quaternary states.
Biochemistry, 52, 2013
7NI9
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BU of 7ni9 by Molmil
Crystal structure of the human METTL3-METTL14 complex with compound UOZ058
分子名称: ACETATE ION, N-(((R)-1-(6-(benzylamino)pyrimidin-4-yl)-3-hydroxypiperidin-3-yl)methyl)-4-(((S)-1-isopropyl-2-azaspiro[3.3]heptan-2-yl)methyl)benzamide, N6-adenosine-methyltransferase catalytic subunit, ...
著者Bedi, R.K, Huang, D, Caflisch, A.
登録日2021-02-11
公開日2021-10-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure-Based Design of Inhibitors of the m6A-RNA Writer Enzyme METTL3
Acs Bio Med Chem Au, 2023

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