7MZC
Cryo-EM structure of minimal TRPV1 with RTX bound in C1 state
Summary for 7MZC
Entry DOI | 10.2210/pdb7mzc/pdb |
EMDB information | 24083 24084 24085 24086 24087 24088 24089 24090 24091 |
Descriptor | Transient receptor potential cation channel subfamily V member 1, resiniferatoxin, SODIUM ION (3 entities in total) |
Functional Keywords | trp channel, cryo-em, nanodisc, vanilloid agonist, transport protein |
Biological source | Rattus norvegicus (Rat) |
Total number of polymer chains | 4 |
Total formula weight | 294626.22 |
Authors | Zhang, K.,Julius, D.,Cheng, Y. (deposition date: 2021-05-24, release date: 2021-09-22, Last modification date: 2021-10-13) |
Primary citation | Zhang, K.,Julius, D.,Cheng, Y. Structural snapshots of TRPV1 reveal mechanism of polymodal functionality. Cell, 184:5138-, 2021 Cited by PubMed: 34496225DOI: 10.1016/j.cell.2021.08.012 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.03 Å) |
Structure validation
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