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PDB: 22297 件

1K5O
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CPI-17(35-120) deletion mutant
分子名称: CPI-17
著者Ohki, S, Eto, M, Kariya, E, Hayano, T, Hayashi, Y, Yazawa, M, Brautigan, D, Kainosho, M.
登録日2001-10-11
公開日2002-10-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of the Myosin Phosphatase Inhibitor Protein CPI-17 Shows Phosphorylation-induced Conformational Changes Responsible for Activation
J.Mol.Biol., 314, 2001
7Q6I
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Vibrio maritimus FtsA 1-396 ATP and FtsN 1-29, bent tetramers in double filament arrangement
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, Cell division protein FtsN (polyAla model), ...
著者Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J.
登録日2021-11-07
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN.
Nat Microbiol, 7, 2022
5JKI
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Crystal structure of the first transmembrane PAP2 type phosphatidylglycerolphosphate phosphatase from Bacillus subtilis
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Putative lipid phosphate phosphatase YodM, TUNGSTATE(VI)ION, ...
著者El Ghachi, M, Howe, N, Lampion, A, Delbrassine, F, Vogeley, L, Caffrey, M, Sauvage, E, Auger, R, Guiseppe, A, Roure, S, Perlier, S, Mengin-lecreulx, D, Foglino, M, Touze, T.
登録日2016-04-26
公開日2017-02-22
最終更新日2017-05-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis.
Cell. Mol. Life Sci., 74, 2017
1K5W
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THREE-DIMENSIONAL STRUCTURE OF THE SYNAPTOTAGMIN 1 C2B-DOMAIN: SYNAPTOTAGMIN 1 AS A PHOSPHOLIPID BINDING MACHINE
分子名称: CALCIUM ION, Synaptotagmin I
著者Fernandez, I, Arac, D, Ubach, J, Gerber, S.H, Shin, O, Gao, Y, Anderson, R.G.W, Sudhof, T.C, Rizo, J.
登録日2001-10-12
公開日2002-01-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Three-dimensional structure of the synaptotagmin 1 C2B-domain: synaptotagmin 1 as a phospholipid binding machine.
Neuron, 32, 2001
1YJ1
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X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
分子名称: CADMIUM ION, CHLORIDE ION, Ubiquitin
著者Bang, D, Makhatadze, G.I, Tereshko, V, Kossiakoff, A.A, Kent, S.B.
登録日2005-01-13
公開日2005-06-14
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献X-ray Crystal Structure of a Chemically Synthesized [D-Gln35]Ubiquitin
Angew.Chem.Int.Ed.Engl., 44, 2005
7Q6G
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Xenorhabdus poinarii FtsA 1-396 ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION
著者Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J.
登録日2021-11-07
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN.
Nat Microbiol, 7, 2022
7Q71
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The crystallographic structure of the Ligand Binding domain of the NR7 nuclear receptor from the amphioxus Branchiostoma lanceolatum
分子名称: CHLORIDE ION, Nuclear hormone receptor 7, PHOSPHATE ION
著者Billas, I.M.L, McEwen, A.G, Hazemann, I, Moras, D, Laudet, V.
登録日2021-11-09
公開日2022-09-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A novel nuclear receptor subfamily enlightens the origin of heterodimerization.
Bmc Biol., 20, 2022
7Q6F
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Vibrio maritimus FtsA 1-396 ATP, double filament
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division protein FtsA, MAGNESIUM ION
著者Nierhaus, T, Kureisaite-Ciziene, D, Lowe, J.
登録日2021-11-07
公開日2022-09-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.31 Å)
主引用文献Bacterial divisome protein FtsA forms curved antiparallel double filaments when binding to FtsN.
Nat Microbiol, 7, 2022
5IZS
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De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity
分子名称: Designed protein 5L6HC3_1
著者Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Oberdorfer, G.
登録日2016-03-25
公開日2016-05-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
1YJE
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Crystal structure of the rNGFI-B ligand-binding domain
分子名称: Orphan nuclear receptor NR4A1
著者Flaig, R, Greschik, H, Peluso-Iltis, C, Moras, D, Structural Proteomics in Europe (SPINE)
登録日2005-01-14
公開日2005-02-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the cell-specific activities of the NGFI-B and the Nurr1 ligand-binding domain.
J.Biol.Chem., 280, 2005
1I5H
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SOLUTION STRUCTURE OF THE RNEDD4 WWIII DOMAIN-RENAL BP2 PEPTIDE COMPLEX
分子名称: AMILORIDE-SENSITIVE SODIUM CHANNEL BETA-SUBUNIT, UBIQUITIN LIGASE NEDD4
著者Kanelis, V, Rotin, D, Forman-Kay, J.D.
登録日2001-02-27
公開日2001-05-02
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a Nedd4 WW domain-ENaC peptide complex.
Nat.Struct.Biol., 8, 2001
4HCY
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Structure of a eukaryotic thiaminase-I bound to the thiamin analogue 3-deazathiamin
分子名称: 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl}ethanol, thiaminase-I
著者Kreinbring, C.A, Hubbard, P.A, Leeper, F.J, Hawksley, D, Petsko, G.A, Ringe, D.
登録日2012-10-01
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of a eukaryotic thiaminase I.
Proc.Natl.Acad.Sci.USA, 111, 2014
5JKG
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The crystal structure of FGFR4 kinase domain in complex with LY2874455
分子名称: 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol, Fibroblast growth factor receptor 4
著者Wu, D, Chen, L, Chen, Y.
登録日2016-04-26
公開日2016-10-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.352 Å)
主引用文献Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455
Plos One, 11, 2016
5J0K
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De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity
分子名称: designed protein 2L4HC2_23
著者Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G.
登録日2016-03-28
公開日2016-05-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity.
Science, 352, 2016
6JF1
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Crystal structure of the substrate binding protein of a methionine transporter from Streptococcus pneumoniae
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Jha, B, Vyas, R, Bhushan, J, Sehgal, D, Biswal, B.K.
登録日2019-02-07
公開日2019-07-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural insights into the substrate specificity of SP_0149, the substrate-binding protein of a methionine ABC transporter from Streptococcus pneumoniae.
Acta Crystallogr.,Sect.F, 75, 2019
5IU4
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Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with ZM241385 at 1.7A resolution
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, ...
著者Segala, E, Guo, D, Cheng, R.K.Y, Bortolato, A, Deflorian, F, Dore, A.S, Errey, J.C, Heitman, L.H, Ijzerman, A.P, Marshall, F.H, Cooke, R.M.
登録日2016-03-17
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength.
J.Med.Chem., 59, 2016
1YJO
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Structure of NNQQNY from yeast prion Sup35 with zinc acetate
分子名称: ACETIC ACID, Eukaryotic peptide chain release factor GTP-binding subunit, ZINC ION
著者Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D.
登録日2005-01-15
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structure of the cross-beta spine of amyloid-like fibrils.
Nature, 435, 2005
1YJP
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Structure of GNNQQNY from yeast prion Sup35
分子名称: Eukaryotic peptide chain release factor GTP-binding subunit
著者Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D.
登録日2005-01-15
公開日2005-06-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the cross-beta spine of amyloid-like fibrils.
Nature, 435, 2005
6JHR
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The cryo-EM structure of HAV bound to a neutralizing antibody-F6
分子名称: FAB Heavy Chain, FAB Light Chain, VP1, ...
著者Cao, L, Liu, P, Yang, P, Gao, Q, Li, H, Sun, Y, Zhu, L, Lin, J, Su, D, Rao, Z, Wang, X.
登録日2019-02-18
公開日2020-03-18
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.
Plos Biol., 17, 2019
6SXW
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Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638)
分子名称: SULFATE ION, Zinc finger protein 638
著者Newman, J.A, Aitkenhead, H, Wang, D, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O.
登録日2019-09-26
公開日2019-10-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638)
To Be Published
6JMF
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Crystal structure of human tyrosine-protein kinase Fes/Fps in complex with compound 4
分子名称: 6-{[(1R,2S)-2-aminocyclohexyl]amino}-5-cyano-2-[(3-methylphenyl)amino]pyridine-3-carboxamide, SULFATE ION, Tyrosine-protein kinase Fes/Fps
著者Baba, D, Hanzawa, H.
登録日2019-03-08
公開日2019-06-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Discovery of Novel Pyrido-pyridazinone Derivatives as FER Tyrosine Kinase Inhibitors with Antitumor Activity.
Acs Med.Chem.Lett., 10, 2019
1W8W
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CBM29-2 mutant Y46A: Probing the Mechanism of Ligand Recognition by Family 29 Carbohydrate Binding Modules
分子名称: NON-CATALYTIC PROTEIN 1
著者Flint, J, Bolam, D.N, Nurizzo, D, Taylor, E.J, Williamson, M.P, Walters, C, Davies, G.J, Gilbert, H.J.
登録日2004-09-30
公開日2005-03-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing the Mechanism of Ligand Recognition in Family 29 Carbohydrate-Binding Modules
J.Biol.Chem., 280, 2005
6IWG
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Crystal structure of rhesus macaque MHC class I molecule Mamu-B*05104 complexed with N-myristoylated 4-mer lipopeptide derived from SIV nef protein
分子名称: 1,2-ETHANEDIOL, BORIC ACID, Beta-2-microglobulin, ...
著者Yamamoto, Y, Morita, D, Sugita, M.
登録日2018-12-05
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification and Structure of an MHC Class I-Encoded Protein with the Potential to PresentN-Myristoylated 4-mer Peptides to T Cells.
J Immunol., 202, 2019
1ICF
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CRYSTAL STRUCTURE OF MHC CLASS II ASSOCIATED P41 II FRAGMENT IN COMPLEX WITH CATHEPSIN L
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (CATHEPSIN L: HEAVY CHAIN), PROTEIN (CATHEPSIN L: LIGHT CHAIN), ...
著者Guncar, G, Pungercic, G, Klemencic, I, Turk, V, Turk, D.
登録日1999-01-07
公開日2000-01-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of MHC class II-associated p41 Ii fragment bound to cathepsin L reveals the structural basis for differentiation between cathepsins L and S.
EMBO J., 18, 1999
6IZR
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Whole structure of a 15-stranded ParM filament from Clostridium botulinum
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Putative plasmid segregation protein ParM
著者Koh, F, Narita, A, Lee, L.J, Tan, Y.Z, Dandey, V.P, Tanaka, K, Popp, D, Robinson, R.C.
登録日2018-12-20
公開日2019-06-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献The structure of a 15-stranded actin-like filament from Clostridium botulinum.
Nat Commun, 10, 2019

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