5VFS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vfs by Molmil](/molmil-images/mine/5vfs) | Nucleotide-Driven Triple-State Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... | 著者 | Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. | 登録日 | 2017-04-09 | 公開日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
|
|
7QLB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qlb by Molmil](/molmil-images/mine/7qlb) | SMYD3 in complex with fragment FL06268 | 分子名称: | 1-methylimidazole-4-sulfonamide, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ... | 著者 | Lund, B.A, Cederfelt, D, Dobritzsch, D. | 登録日 | 2021-12-20 | 公開日 | 2023-03-29 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening Rsc Med Chem, 2024
|
|
5VIE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vie by Molmil](/molmil-images/mine/5vie) | Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase | 分子名称: | 2-{[(2E)-4-chlorobut-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, 2-{[(2E)-but-2-enoyl]amino}-2-deoxy-beta-D-glucopyranose, CKII, ... | 著者 | Jiang, J, Li, B, Hu, C.-W, Worth, M, Fan, D, Li, H. | 登録日 | 2017-04-15 | 公開日 | 2017-10-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase. Nat. Chem. Biol., 13, 2017
|
|
7QNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qnu by Molmil](/molmil-images/mine/7qnu) | SMYD3 in complex with fragment FL08619 | 分子名称: | BENZOYL-FORMIC ACID, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ... | 著者 | Lund, B.A, Cederfelt, D, Dobritzsch, D. | 登録日 | 2021-12-22 | 公開日 | 2023-04-05 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening Rsc Med Chem, 2024
|
|
5VFU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vfu by Molmil](/molmil-images/mine/5vfu) | Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome | 分子名称: | 26S protease regulatory subunit 10B, 26S protease regulatory subunit 4, 26S protease regulatory subunit 6A, ... | 著者 | Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. | 登録日 | 2017-04-09 | 公開日 | 2018-07-18 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
|
|
7QNR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qnr by Molmil](/molmil-images/mine/7qnr) | SMYD3 in complex with fragment FL01791 | 分子名称: | 3-propan-2-yl-1,2,4-thiadiazol-5-amine, Histone-lysine N-methyltransferase SMYD3, S-ADENOSYLMETHIONINE, ... | 著者 | Lund, B.A, Cederfelt, D, Dobritzsch, D. | 登録日 | 2021-12-22 | 公開日 | 2023-04-05 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening Rsc Med Chem, 2024
|
|
5VIA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5via by Molmil](/molmil-images/mine/5via) | |
5VFT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vft by Molmil](/molmil-images/mine/5vft) | Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 12, ... | 著者 | Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. | 登録日 | 2017-04-09 | 公開日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (7 Å) | 主引用文献 | Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
|
|
5W3Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w3q by Molmil](/molmil-images/mine/5w3q) | L28F E.coli DHFR in complex with NADPH | 分子名称: | CALCIUM ION, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Oyen, D, Wright, P.E, Wilson, I.A. | 登録日 | 2017-06-08 | 公開日 | 2017-08-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | Defining the Structural Basis for Allosteric Product Release from E. coli Dihydrofolate Reductase Using NMR Relaxation Dispersion. J. Am. Chem. Soc., 139, 2017
|
|
5VFO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vfo by Molmil](/molmil-images/mine/5vfo) | Nucleotide-driven Triple-state Remodeling of the AAA-ATPase Channel in the Activated Human 26S Proteasome | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | 著者 | Zhu, Y, Wang, W.L, Yu, D, Ouyang, Q, Lu, Y, Mao, Y. | 登録日 | 2017-04-08 | 公開日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome. Nat Commun, 9, 2018
|
|
5VHM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vhm by Molmil](/molmil-images/mine/5vhm) | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle | 分子名称: | 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... | 著者 | Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. | 登録日 | 2017-04-13 | 公開日 | 2017-08-23 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (8.3 Å) | 主引用文献 | Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell, 67, 2017
|
|
5VKQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vkq by Molmil](/molmil-images/mine/5vkq) | Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L | 著者 | Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y. | 登録日 | 2017-04-22 | 公開日 | 2017-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature, 547, 2017
|
|
5VR0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5vr0 by Molmil](/molmil-images/mine/5vr0) | |
7MJR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mjr by Molmil](/molmil-images/mine/7mjr) | Vip4Da2 toxin structure | 分子名称: | CALCIUM ION, SULFATE ION, Vip4Da1 protein | 著者 | Rydel, T.J, Duda, D, Zheng, M, Henry, A. | 登録日 | 2021-04-20 | 公開日 | 2021-05-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Structural and functional insights into the first Bacillus thuringiensis vegetative insecticidal protein of the Vpb4 fold, active against western corn rootworm. Plos One, 16, 2021
|
|
7MHF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mhf by Molmil](/molmil-images/mine/7mhf) | Crystal Structure of SARS-CoV-2 Main Protease (Mpro) at 100 K | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ZINC ION | 著者 | Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A. | 登録日 | 2021-04-15 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The tem-per-ature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ). Iucrj, 9, 2022
|
|
7MHG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mhg by Molmil](/molmil-images/mine/7mhg) | Crystal Structure of SARS-CoV-2 Main Protease (Mpro) at 240 K | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ZINC ION | 著者 | Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A. | 登録日 | 2021-04-15 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5302 Å) | 主引用文献 | The tem-per-ature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ). Iucrj, 9, 2022
|
|
5E0Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5e0q by Molmil](/molmil-images/mine/5e0q) | |
7MHL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mhl by Molmil](/molmil-images/mine/7mhl) | Ensemble refinement structure of SARS-CoV-2 main protease (Mpro) at 100 K | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ZINC ION | 著者 | Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A. | 登録日 | 2021-04-15 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The tem-per-ature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ). Iucrj, 9, 2022
|
|
7MHM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mhm by Molmil](/molmil-images/mine/7mhm) | Ensemble refinement structure of SARS-CoV-2 main protease (Mpro) at 240 K | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ZINC ION | 著者 | Ebrahim, A, Riley, B.T, Kumaran, D, Andi, B, Fuchs, M.R, McSweeney, S, Keedy, D.A. | 登録日 | 2021-04-15 | 公開日 | 2021-05-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.5302 Å) | 主引用文献 | The tem-per-ature-dependent conformational ensemble of SARS-CoV-2 main protease (M pro ). Iucrj, 9, 2022
|
|
4O5T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o5t by Molmil](/molmil-images/mine/4o5t) | Crystal structure of Diels-Alderase CE20 in complex with a product analog | 分子名称: | 4-{[2-(phosphonooxy)ethyl]carbamoyl}benzyl [(1R,6S)-6-(dimethylcarbamoyl)cyclohex-2-en-1-yl]carbamate, Diisopropyl-fluorophosphatase | 著者 | Beck, T, Preiswerk, N, Mayer, C, Hilvert, D. | 登録日 | 2013-12-20 | 公開日 | 2014-06-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
2XPE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xpe by Molmil](/molmil-images/mine/2xpe) | Oxidised Thiol peroxidase (Tpx) from Yersinia pseudotuberculosis | 分子名称: | THIOL PEROXIDASE | 著者 | Gabrielsen, M, Zetterstrom, C.E, Wang, D, Elofsson, M, Roe, A.J. | 登録日 | 2010-08-26 | 公開日 | 2011-08-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Characterisation of Tpx from Yersinia Pseudotuberculosis Reveals Insights Into the Binding of Salicylidene Acylhydrazide Compounds. Plos One, 7, 2012
|
|
2XBQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xbq by Molmil](/molmil-images/mine/2xbq) | Crystal structure of reduced Schistosoma mansoni Thioredoxin pre- protein at 1.7 Angstrom | 分子名称: | THIOREDOXIN, ZINC ION | 著者 | Boumis, G, Miele, A.E, Dimastrogiovanni, D, Angelucci, F, Bellelli, A. | 登録日 | 2010-04-14 | 公開日 | 2010-07-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural and Functional Characterization of Schistosoma Mansoni Thioredoxin. Protein Sci., 20, 2011
|
|
6KJ4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6kj4 by Molmil](/molmil-images/mine/6kj4) | 120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A | 分子名称: | RNA-binding protein FUS | 著者 | Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. | 登録日 | 2019-07-20 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (0.65 Å) | 主引用文献 | Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules. Anal.Chem., 91, 2019
|
|
4O5S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o5s by Molmil](/molmil-images/mine/4o5s) | |
8E55
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e55 by Molmil](/molmil-images/mine/8e55) | |