2VY3
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![BU of 2vy3 by Molmil](/molmil-images/mine/2vy3) | Type IV secretion system effector protein BepA | Descriptor: | CELL FILAMENTATION PROTEIN, CHLORIDE ION, NICKEL (II) ION | Authors: | Palanivelu, D.V, Schirmer, T. | Deposit date: | 2008-07-17 | Release date: | 2009-11-17 | Last modified: | 2011-11-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Fic Domain Catalyzed Adenylylation: Insight Provided by the Structural Analysis of the Type Iv Secretion System Effector Bepa. Protein Sci., 20, 2011
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4V7C
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![BU of 4v7c by Molmil](/molmil-images/mine/4v7c) | Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA structure) | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N. | Deposit date: | 2013-11-20 | Release date: | 2014-07-09 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (7.6 Å) | Cite: | Structure of the ribosome with elongation factor G trapped in the pretranslocation state. Proc.Natl.Acad.Sci.USA, 110, 2013
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4V8T
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![BU of 4v8t by Molmil](/molmil-images/mine/4v8t) | Cryo-EM Structure of the 60S Ribosomal Subunit in Complex with Arx1 and Rei1 | Descriptor: | 25S RIBOSOMAL RNA, 5.8S RIBOSOMAL RNA, 5S RIBOSOMAL RNA, ... | Authors: | Greber, B.J, Boehringer, D, Montellese, C, Ban, N. | Deposit date: | 2012-08-07 | Release date: | 2014-07-09 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (8.1 Å) | Cite: | Cryo-Em Structures of Arx1 and Maturation Factors Rei1 and Jjj1 Bound to the 60S Ribosomal Subunit Nat.Struct.Mol.Biol., 19, 2012
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6PQ0
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![BU of 6pq0 by Molmil](/molmil-images/mine/6pq0) | LCP-embedded Proteinase K treated with MPD | Descriptor: | CALCIUM ION, Proteinase K | Authors: | Bu, G, Zhu, L, Jing, L, Shi, D, Gonen, T, Liu, W, Nannenga, B.L. | Deposit date: | 2019-07-08 | Release date: | 2020-08-05 | Last modified: | 2023-10-11 | Method: | ELECTRON CRYSTALLOGRAPHY (2 Å) | Cite: | Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED. Structure, 28, 2020
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2IF5
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![BU of 2if5 by Molmil](/molmil-images/mine/2if5) | Structure of the POZ domain of human LRF, a master regulator of oncogenesis | Descriptor: | PRASEODYMIUM ION, Zinc finger and BTB domain-containing protein 7A | Authors: | Schubot, F.D, Waugh, D.S, Tropea, J. | Deposit date: | 2006-09-20 | Release date: | 2006-11-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the POZ domain of human LRF, a master regulator of oncogenesis. Biochem.Biophys.Res.Commun., 351, 2006
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7ZYN
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![BU of 7zyn by Molmil](/molmil-images/mine/7zyn) | Crystal Structure of EGFR-T790M/C797S in Complex with WZ4002 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, N-{3-[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide | Authors: | Niggenaber, J, Kleinboelting, S, Mueller, M.P, Rauh, D. | Deposit date: | 2022-05-25 | Release date: | 2023-05-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. Acs Med.Chem.Lett., 14, 2023
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2WAA
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![BU of 2waa by Molmil](/molmil-images/mine/2waa) | Structure of a family two carbohydrate esterase from Cellvibrio japonicus | Descriptor: | ACETATE ION, GLYCEROL, XYLAN ESTERASE, ... | Authors: | Montainer, C, Money, V.A, Pires, V.M.R, Flint, J.E, Pinheiro, B.A, Goyal, A, Prates, J.A.M, Izumi, A, Stalbrand, H, Kolenova, K, Topakas, E, Dodson, E.J, Bolam, D.N, Davies, G.J, Fontes, C.M.G.A, Gilbert, H.J. | Deposit date: | 2009-02-04 | Release date: | 2009-03-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Active Site of a Carbohydrate Esterase Displays Divergent Catalytic and Noncatalytic Binding Functions. Plos Biol., 7, 2009
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2W1J
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![BU of 2w1j by Molmil](/molmil-images/mine/2w1j) | CRYSTAL STRUCTURE OF SORTASE C-1 (SRTC-1) from Streptococcus pneumoniae | Descriptor: | GLYCEROL, PUTATIVE SORTASE | Authors: | Manzano, C, Contreras-Martel, C, El Mortaji, L, Izore, T, Fenel, D, Vernet, T, Schoehn, G, Di Guilmi, A.M, Dessen, A. | Deposit date: | 2008-10-17 | Release date: | 2008-12-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Sortase-Mediated Pilus Fiber Biogenesis in Streptococcus Pneumoniae. Structure, 16, 2008
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8ISC
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![BU of 8isc by Molmil](/molmil-images/mine/8isc) | Crystal structure of MV in complex with LLP | Descriptor: | Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase | Authors: | Li, Q, Zhu, Y.M, Gao, J, Wei, H.L, Han, X, Liu, W.D, Sun, Y.X. | Deposit date: | 2023-03-20 | Release date: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Crystal structure of MV in complex with LLP To Be Published
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2II0
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![BU of 2ii0 by Molmil](/molmil-images/mine/2ii0) | Crystal Structure of catalytic domain of Son of sevenless (Rem-Cdc25) in the absence of Ras | Descriptor: | Son of sevenless homolog 1 | Authors: | Freedman, T.S, Sondermann, H, Friedland, G.D, Kortemme, T, Bar-Sagi, D, Marqusee, S, Kuriyan, J. | Deposit date: | 2006-09-27 | Release date: | 2006-10-31 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | A Ras-induced conformational switch in the Ras activator Son of sevenless. Proc.Natl.Acad.Sci.Usa, 103, 2006
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5D2T
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![BU of 5d2t by Molmil](/molmil-images/mine/5d2t) | |
7ZYP
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![BU of 7zyp by Molmil](/molmil-images/mine/7zyp) | Crystal Structure of EGFR-T790M/C797S in Complex with Reversible Aminopyrimidine 9 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Epidermal growth factor receptor, propan-2-yl 2-[[4-(4-azanylpiperidin-1-yl)-2-methoxy-phenyl]amino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate | Authors: | Niggenaber, J, Kleinboelting, S, Mueller, M.P, Rauh, D. | Deposit date: | 2022-05-25 | Release date: | 2023-05-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Addressing the Osimertinib Resistance Mutation EGFR-L858R/C797S with Reversible Aminopyrimidines. Acs Med.Chem.Lett., 14, 2023
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2IJ5
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![BU of 2ij5 by Molmil](/molmil-images/mine/2ij5) | |
2W5R
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![BU of 2w5r by Molmil](/molmil-images/mine/2w5r) | Structure-based mechanism of lipoteichoic acid synthesis by Staphylococcus aureus LtaS. | Descriptor: | (2R)-2,3-dihydroxypropyl phosphate, ACETATE ION, MANGANESE (II) ION, ... | Authors: | Lu, D, Wormann, M.E, Zhang, X, Schneewind, O, Grundling, A, Freemont, P.S. | Deposit date: | 2008-12-11 | Release date: | 2009-02-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-Based Mechanism of Lipoteichoic Acid Synthesis by Staphylococcus Aureus Ltas. Proc.Natl.Acad.Sci.USA, 106, 2009
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8I3Y
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![BU of 8i3y by Molmil](/molmil-images/mine/8i3y) | Crystal structure of ASCT from Trypanosoma brucei in complex with Succinyl-CoA. | Descriptor: | CALCIUM ION, SUCCINIC ACID, SUCCINYL-COENZYME A, ... | Authors: | Mochizuki, K, Inaoka, D.K, Fukuda, K, Kurasawa, H, Iyoda, K, Nakai, U, Harada, S, Balogun, E.O, Mazet, M, Millerioux, Y, Bringaud, F, Boshart, M, Hirayama, K, Kita, K, Shiba, T. | Deposit date: | 2023-01-18 | Release date: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of ASCT from Trypanosoma brucei in complex with Succinyl-CoA. To Be Published
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6PRH
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![BU of 6prh by Molmil](/molmil-images/mine/6prh) | |
2WB5
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![BU of 2wb5 by Molmil](/molmil-images/mine/2wb5) | GlcNAcstatins are nanomolar inhibitors of human O-GlcNAcase inducing cellular hyper-O-GlcNAcylation | Descriptor: | (5R,6R,7R,8S)-6,7-dihydroxy-5-(hydroxymethyl)-2-(2-phenylethyl)-8-(propanoylamino)-5,6,7,8-tetrahydro-1H-imidazo[1,2-a]pyridin-4-ium, CHLORIDE ION, O-GLCNACASE NAGJ, ... | Authors: | Dorfmueller, H.C, Borodkin, V.S, Schimpl, M, van Aalten, D.M.F. | Deposit date: | 2009-02-20 | Release date: | 2009-03-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Glcnacstatins are Nanomolar Inhibitors of Human O-Glcnacase Inducing Cellular Hyper-O-Glcnacylation Biochem.J., 420, 2009
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1TK6
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![BU of 1tk6 by Molmil](/molmil-images/mine/1tk6) | Iron-oxo clusters biomineralizing on protein surfaces. Structural analysis of H.salinarum DpsA in its low and high iron states | Descriptor: | FE (III) ION, Iron-rich dpsA-homolog protein, MAGNESIUM ION, ... | Authors: | Zeth, K, Offermann, S, Essen, L.O, Oesterhelt, D. | Deposit date: | 2004-06-08 | Release date: | 2004-10-19 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Iron-oxo clusters biomineralizing on protein surfaces: structural analysis of Halobacterium salinarum DpsA in its low- and high-iron states. Proc.Natl.Acad.Sci.USA, 101, 2004
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4RGF
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![BU of 4rgf by Molmil](/molmil-images/mine/4rgf) | Crystal structure of the in-line aligned env22 twister ribozyme soaked with Mn2+ | Descriptor: | MAGNESIUM ION, MANGANESE (II) ION, POTASSIUM ION, ... | Authors: | Ren, A, Rajashankar, K.R, Simanshu, D, Patel, D. | Deposit date: | 2014-09-30 | Release date: | 2014-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.2008 Å) | Cite: | In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme. Nat Commun, 5, 2014
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4RGE
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![BU of 4rge by Molmil](/molmil-images/mine/4rge) | Crystal structure of the in-line aligned env22 twister ribozyme | Descriptor: | MAGNESIUM ION, env22 twister ribozyme | Authors: | Ren, A, Rajashankar, K.R, Simanshu, D, Patel, D. | Deposit date: | 2014-09-30 | Release date: | 2014-12-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | In-line alignment and Mg(2+) coordination at the cleavage site of the env22 twister ribozyme. Nat Commun, 5, 2014
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8HWL
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![BU of 8hwl by Molmil](/molmil-images/mine/8hwl) | Human Pyruvate Carboxylase | Descriptor: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial | Authors: | Liu, D.S, Su, J.Y. | Deposit date: | 2022-12-30 | Release date: | 2024-01-31 | Method: | ELECTRON MICROSCOPY (5.63 Å) | Cite: | Human Pyruvate Carboxylase To Be Published
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2VRL
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![BU of 2vrl by Molmil](/molmil-images/mine/2vrl) | Structure of human MAO B in complex with benzylhydrazine | Descriptor: | AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, TOLUENE | Authors: | Binda, C, Wang, J, Li, M, Hubalek, F, Mattevi, A, Edmondson, D.E. | Deposit date: | 2008-04-09 | Release date: | 2008-04-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and Mechanistic Studies of Arylalkylhydrazine Inhibition of Human Monoamine Oxidases a and B Biochemistry, 47, 2008
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5CYU
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![BU of 5cyu by Molmil](/molmil-images/mine/5cyu) | Structure of the soluble domain of EccB1 from the Mycobacterium smegmatis ESX-1 secretion system. | Descriptor: | Conserved membrane protein | Authors: | Arbing, M.A, Chan, S, Kahng, S, Kim, J, Eisenberg, D.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2015-07-30 | Release date: | 2015-08-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. Bmc Struct.Biol., 16, 2016
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8IA6
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![BU of 8ia6 by Molmil](/molmil-images/mine/8ia6) | |
2VRM
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![BU of 2vrm by Molmil](/molmil-images/mine/2vrm) | Structure of human MAO B in complex with phenyethylhydrazine | Descriptor: | AMINE OXIDASE [FLAVIN-CONTAINING] B, FLAVIN-ADENINE DINUCLEOTIDE, PHENYLETHANE | Authors: | Binda, C, Wang, J, Li, M, Hubalek, F, Mattevi, A, Edmondson, D.E. | Deposit date: | 2008-04-09 | Release date: | 2008-04-22 | Last modified: | 2014-01-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Mechanistic Studies of Arylalkylhydrazine Inhibition of Human Monoamine Oxidases a and B Biochemistry, 47, 2008
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